Search Results - "Millecchia, L L"

Nitric Oxide and Reactive Oxygen Species Production Causes Progressive Damage in Rats after Cessation of Silica Inhalation by Porter, Dale W., Millecchia, Lyndell L., Willard, Patsy, Robinson, Victor A., Ramsey, Dawn, McLaurin, Jeffery, Khan, Amir, Brumbaugh, Kurt, Beighley, Christoper M., Teass, Alexander, Castranova, Vincent

“…Our laboratory has previously reported results from a rat silica inhalation study which determined that, even after silica exposure ended, pulmonary…”
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Identification of a Novel Domain at the N Terminus of Caveolin-1 That Controls Rear Polarization of the Protein and Caveolae Formation by Sun, Xing-Hui, Flynn, Daniel C., Castranova, Vincent, Millecchia, Lyndell L., Beardsley, Andrew R., Liu, Jun

“…When cells are migrating, caveolin-1, the principal protein component of caveolae, is excluded from the leading edge and polarized at the cell rear. The…”
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Treatment and histopathology of a congenital vitreous cyst by Nork, T M, Millecchia, L L

“…This study aimed to evaluate the treatment efficacy of a congenital vitreous cyst and to examine the cyst histopathologically to determine its cellular makeup…”
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Localization of Species-Specific Antibody Binding Sites to Stachybotrys Chartarum Using the Halogen Immunoassay by Green, B.J., Schmechel, D., Millecchia, L., Blachere, F., Beezhold, D.

“…The purpose of this study was to use the Halogen Immunoassay (HIA) to characterize the antibody binding sites of a recently developed S. chartarum monoclonal…”
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Hyperosmolar solution effects in guinea pig airways. IV. Lipopolysaccharide-induced alterations in airway reactivity and epithelial bioelectric responses to methacholine and hyperosmolarity by Johnston, Richard A, Van Scott, Michael R, Kommineni, Choudari, Millecchia, Lyndell L, Dortch-Carnes, Juanita, Fedan, Jeffrey S

“…We investigated the in vivo and in vitro effects of lipopolysaccharide (LPS) treatment (4 mg/kg i.p.) on guinea pig airway smooth muscle reactivity and…”
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Effects of paving asphalt fume exposure on genotoxic and mutagenic activities in the rat lung by Zhao, H.W, Yin, X.J, Frazer, D, Barger, M.W, Siegel, P.D, Millecchia, L, Zhong, B.Z, Tomblyn, S, Stone, S, Ma, J.K.H, Castranova, V, Ma, J.Y.C

“…Asphalt fumes are complex mixtures of aerosols and vapors containing various organic compounds, including polycyclic aromatic hydrocarbons (PAHs). Previously,…”
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Swelling and loss of photoreceptors in chronic human and experimental glaucomas by Nork, T M, Ver Hoeve, J N, Poulsen, G L, Nickells, R W, Davis, M D, Weber, A J, Vaegan, Sarks, S H, Lemley, H L, Millecchia, L L

“…To determine whether outer retinal changes occur in chronic, presumed primary open-angle glaucoma (POAG). The outer retinas from 128 human eyes with a…”
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Effect of ozone treatment on airway reactivity and epithelium-derived relaxing factor in guinea pigs by Fedan, J S, Millecchia, L L, Johnston, R A, Rengasamy, A, Hubbs, A, Dey, R D, Yuan, L X, Watson, D, Goldsmith, W T, Reynolds, J S, Orsini, L, Dortch-Carnes, J, Cutler, D, Frazer, D G

“…Ozone (O(3)) is toxic to respiratory epithelium and causes airway inflammation and hyperreactivity. To evaluate the role of the epithelium in the development…”
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Fluticasone propionate and pentamidine isethionate reduce airway hyperreactivity, pulmonary eosinophilia and pulmonary dendritic cell response in a guinea pig model of asthma by Lawrence, T E, Millecchia, L L, Fedan, J S

“…In this study, we examined the effects of fluticasone propionate (FP) and pentamidine isethionate (PI) on antigen-induced lung inflammation and airway…”
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Nitric oxide production by rat bronchoalveolar macrophages or polymorphonuclear leukocytes following intratracheal instillation of lipopolysaccharide or silica by Huffman, L J, Prugh, D J, Millecchia, L, Schuller, K C, Cantrell, S, Porter, D W

“…Exposure of the lung to lipopolysaccharide (LPS) or silica results in an activation of alveolar macrophages (AMs), recruitment of polymorphonuclear leukocytes…”
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Role of inducible nitric oxide synthase-derived nitric oxide in lipopolysaccharide plus interferon-γ-induced pulmonary inflammation by Zeidler, Patti C., Millecchia, Lyndell M., Castranova, Vincent

“…Exposure of mice to lipopolysaccharide (LPS) plus interferon-γ (IFN-γ) increases nitric oxide (NO) production, which is proposed to play a role in the…”
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Pulmonary dendritic cell distribution and prevalence in guinea pig airways: effect of ovalbumin sensitization and challenge by Lawrence, T E, Millecchia, L L, Frazer, D G, Fedan, J S

“…We characterized the localization and prevalence of dendritic cells (DC) in guinea pig airways before and after s.c. sensitization and aerosol challenge with…”
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Rods and cones contain antigenically distinctive S-antigens by Nork, TM, Mangini, NJ, Millecchia, LL

“…S-antigen (48 kDa protein or arrestin) is known to be present in rod photoreceptors. Its localization in cones is less clear with several conflicting reports…”
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Brief exposure of air-filled guinea-pig isolated trachea to low levels of toluene diisocyanate (TDI) vapor in vitro increases reactivity to methacholine by Huang, Jun, Frazer, David G, Millecchia, Lyndell L, Fedan, Jeffrey S

“…Toluene diisocyanate (TDI) causes occupational asthma characterized by inflammation and hyperreactivity of airways to irritants and bronchoconstrictor drugs…”
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OVALBUMIN AEROALLERGEN EXPOSURE-RESPONSE IN BROWN NORWAY RATS by Siegel, P D, Al-Humadi, N H, Millecchia, L L, Robinson, V A, Hubbs, A F, Nelson, E R, Fedan, J S

“…A major route of exposure to allergens is through the respiratory tract. Comparatively few animal studies have used aerosolized high-molecular-weight allergens…”
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Airway hyperreactivity elicited by toluene diisocyanate (TDI)-albumin conjugate is not accompanied by airway eosinophilic infiltration in guinea pigs by JUN HUANG, MILLECCHIA, L. L, FRAZER, D. G, FEDAN, J. S

“…Nonspecific airway hyperresponsiveness is present in many patients with toluene diisocyanate (TDI)-induced asthma; however, the underlying pathophysiological…”
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Immunolocalization of the retinoblastoma protein in the human eye and in retinoblastoma by Nork, TM, Millecchia, LL, Poulsen, G

“…To determine whether, by employing recent advances in immunocytochemical technique, it is possible to identify reliably the product of the retinoblastoma (RB)…”
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Systemic Microvascular Dysfunction and Inflammation after Pulmonary Particulate Matter Exposure by Nurkiewicz, Timothy R., Porter, Dale W., Barger, Mark, Millecchia, Lyndell, K. Murali K. Rao, Marvar, Paul J., Hubbs, Ann F., Castranova, Vincent, Boegehold, Matthew A.

“…The epidemiologic association between pulmonary exposure to ambient particulate matter (PM) and cardiovascular dysfunction is well known, but the systemic…”
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p53 regulates apoptosis in human retinoblastoma by Nork, T M, Poulsen, G L, Millecchia, L L, Jantz, R G, Nickells, R W

“…To determine whether apoptosis is a significant mode of cell death in human retinoblastoma (RB) and if it is regulated by the expression of p53. Apoptosis was…”
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Dual fluorescent halogen immunoassay for bioaerosols using confocal microscopy by Green, Brett J., Millecchia, Lyndell L., Blachere, Francoise M., Tovey, Euan R., Beezhold, Donald H., Schmechel, Detlef

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