Search Results - "Millar, Jonathan B."
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KNL1-Bubs and RZZ Provide Two Separable Pathways for Checkpoint Activation at Human Kinetochores
Published in Developmental cell (07-12-2015)“…The spindle assembly checkpoint (SAC) ensures the accurate segregation of sister chromatids during mitosis. Activation of the SAC occurs through a series of…”
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Spindle Checkpoint Silencing Requires Association of PP1 to Both Spc7 and Kinesin-8 Motors
Published in Developmental cell (14-06-2011)“…The spindle checkpoint is the prime cell-cycle control mechanism that ensures sister chromatids are bioriented before anaphase takes place. Aurora B kinase,…”
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Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint
Published in Current biology (22-05-2012)“…The spindle assembly checkpoint (SAC) is the major surveillance system that ensures that sister chromatids do not separate until all chromosomes are correctly…”
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4
Phosphoregulation of tropomyosin is crucial for actin cable turnover and division site placement
Published in The Journal of cell biology (04-11-2019)“…Tropomyosin is a coiled-coil actin binding protein key to the stability of actin filaments. In muscle cells, tropomyosin is subject to calcium regulation, but…”
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Cdc25: mechanisms of checkpoint inhibition and recovery
Published in Trends in cell biology (01-06-2006)“…Members of the eukaryotic Cdc25 phosphatase family are key targets of the Chk1 and Chk2 checkpoint kinases, which inactivate Cdc25 to halt cell cycle…”
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Dam1/DASH complex is required for the retrieval of unclustered kinetochores in fission yeast
Published in Journal of cell science (01-10-2007)“…In fission yeast centromeres cluster at the nuclear envelope in a region underlying the spindle pole body during interphase, an arrangement known as a Rabl…”
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Role and regulation of kinesin-8 motors through the cell cycle
Published in Systems and synthetic biology (01-09-2014)“…Members of the kinesin-8 motor family play a central role in controlling microtubule length throughout the eukaryotic cell cycle. Inactivation of kinesin-8…”
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Monopolin subunit Csm1 associates with MIND complex to establish monopolar attachment of sister kinetochores at meiosis I
Published in PLoS genetics (01-07-2013)“…Sexually reproducing organisms halve their cellular ploidy during gametogenesis by undergoing a specialized form of cell division known as meiosis. During…”
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A genomic approach to studying cell-size homeostasis in yeast
Published in Genome biology (20-09-2002)“…Using a complete set of budding-yeast mutants bearing deletions of all known open reading frames, a recent study has revealed multiple overlapping pathways…”
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Control of the eukaryotic cell cycle by MAP kinase signaling pathways
Published in The FASEB journal (01-11-2000)“…ABSTRACT In an often rapidly changing environment, cells must adapt by monitoring and reacting quickly to extracellular stimuli detected by membrane‐bound…”
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Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B
Published in Molecular biology of the cell (01-12-2011)“…Type 1 phosphatase (PP1) antagonizes Aurora B kinase to stabilize kinetochore-microtubule attachments and to silence the spindle checkpoint. We screened for…”
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The Rim15-endosulfine-PP2ACdc55 signalling module regulates entry into gametogenesis and quiescence via distinct mechanisms in budding yeast
Published in PLoS genetics (01-06-2014)“…Quiescence and gametogenesis represent two distinct survival strategies in response to nutrient starvation in budding yeast. Precisely how environmental…”
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13
Opposing kinesin complexes queue at plus tips to ensure microtubule catastrophe at cell ends
Published in EMBO reports (01-11-2018)“…In fission yeast, the lengths of interphase microtubule (iMT) arrays are adapted to cell length to maintain cell polarity and to help centre the nucleus and…”
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Fkh2p and Sep1p regulate mitotic gene transcription in fission yeast
Published in Journal of cell science (01-11-2004)“…In the fission yeast Schizosaccharomyces pombe, several genes including cdc15+, spo12+, fin1+, slp1+, ace2+ and plo1+ are periodically expressed during M…”
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Some assembly required: Redefining the mitotic checkpoint
Published in Molecular & cellular oncology (02-11-2017)“…The spindle assembly checkpoint (also known as the spindle or mitotic checkpoint) is a surveillance system that ensures fidelity of chromosome segregation…”
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Plo1 phosphorylates Dam1 to promote chromosome bi-orientation in fission yeast
Published in Journal of cell science (01-04-2012)“…The fungal-specific heterodecameric outer kinetochore DASH complex facilitates the interaction of kinetochores with spindle microtubules. In budding yeast,…”
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Ringing the changes: emerging roles for DASH at the kinetochore-microtubule Interface
Published in Chromosome research (01-04-2011)“…Regulated interaction between kinetochores and the mitotic spindle is essential for the fidelity of chromosome segregation. Potentially deleterious attachments…”
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Human Papillomavirus Type 16 E1∧E4-Induced G2 Arrest Is Associated with Cytoplasmic Retention of Active Cdk1/Cyclin B1 Complexes
Published in Journal of Virology (01-04-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Forkhead Transcription Factor Fkh2 Regulates the Cell Division Cycle of Schizosaccharomyces pombe
Published in Eukaryotic Cell (01-08-2004)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Bub3-Bub1 Binding to Spc7/KNL1 Toggles the Spindle Checkpoint Switch by Licensing the Interaction of Bub1 with Mad1-Mad2
Published in Current biology (10-10-2016)“…The spindle assembly checkpoint (SAC) ensures that sister chromatids do not separate until all chromosomes are attached to spindle microtubules and…”
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