Search Results - "Millar, B.A"

Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint by Shepperd, Lindsey A., Meadows, John C., Sochaj, Alicja M., Lancaster, Theresa C., Zou, Juan, Buttrick, Graham J., Rappsilber, Juri, Hardwick, Kevin G., Millar, Jonathan B.A.

“…The spindle assembly checkpoint (SAC) is the major surveillance system that ensures that sister chromatids do not separate until all chromosomes are correctly…”
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Distinct Regulatory Proteins Control the Graded Transcriptional Response to Increasing H2O2 Levels in Fission Yeast Schizosaccharomyces pombe by Quinn, Janet, Findlay, Victoria J., Dawson, Keren, Millar, Jonathan B.A., Jones, Nic, Morgan, Brian A., Toone, W. Mark

“…The signaling pathways that sense adverse stimuli and communicate with the nucleus to initiate appropriate changes in gene expression are central to the…”
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EP-1800: Determining an imaging literacy curriculum for radiation oncologists: An international Delphi study by Giuliani, M, Gillan, C, Milne, R, Uchino, M, Millar, B.A, Catton, P

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Local Tumor Flare Following Radiosurgery and Ipilimumab (Ipi) for Melanoma Brain Metastases: Increased Immune Response? by Chung, C, Khoja, L, Kurtz, G, Bernstein, M, Joshua, A, Hogg, D, Zadeh, G, Laperriere, N, Menard, C, Millar, B.A, Kongkham, P, Butler, M

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Cdc25: mechanisms of checkpoint inhibition and recovery by Karlsson-Rosenthal, Christina, Millar, Jonathan B.A.

“…Members of the eukaryotic Cdc25 phosphatase family are key targets of the Chk1 and Chk2 checkpoint kinases, which inactivate Cdc25 to halt cell cycle…”
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Two-component mediated peroxide sensing and signal transduction in fission yeast by Quinn, Janet, Malakasi, Panagiota, Smith, Deborah A, Cheetham, Jill, Buck, Vicky, Millar, Jonathan B A, Morgan, Brian A

“…Two-component related proteins play a major role in regulating the oxidative stress response in the fission yeast, Schizosaccharomyces pombe. For example, the…”
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Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway by Buck, V, Quinn, J, Soto Pino, T, Martin, H, Saldanha, J, Makino, K, Morgan, B A, Millar, J B

“…The Schizosaccharomyces pombe stress-activated Sty1p/Spc1p mitogen-activated protein (MAP) kinase regulates gene expression through the Atf1p and Pap1p…”
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Bub3p facilitates spindle checkpoint silencing in fission yeast by Vanoosthuyse, Vincent, Meadows, John C, van der Sar, Sjaak J A, Millar, Jonathan B A, Hardwick, Kevin G

“…Although critical for spindle checkpoint signaling, the role kinetochores play in anaphase promoting complex (APC) inhibition remains unclear. Here we show…”
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Cell Biology: Polar Expeditions for PP1 by Meadows, John C., Millar, Jonathan B.A.

“…A new study shows that phospho-dependent expulsion of type-1-phosphatase (PP1) from the spindle pole by Fin1 (NIMA) kinase ensures switch-like activation of…”
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Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast by Meadows, John C., Lancaster, Theresa C., Buttrick, Graham J., Sochaj, Alicja M., Messin, Liam J., del Mar Mora-Santos, Maria, Hardwick, Kevin G., Millar, Jonathan B.A.

“…The onset of anaphase is triggered by activation of the anaphase-promoting complex/cyclosome (APC/C) following silencing of the spindle assembly checkpoint…”
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Bub3-Bub1 Binding to Spc7/KNL1 Toggles the Spindle Checkpoint Switch by Licensing the Interaction of Bub1 with Mad1-Mad2 by Mora-Santos, Maria del Mar, Hervas-Aguilar, America, Sewart, Katharina, Lancaster, Theresa C., Meadows, John C., Millar, Jonathan B.A.

“…The spindle assembly checkpoint (SAC) ensures that sister chromatids do not separate until all chromosomes are attached to spindle microtubules and…”
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Spindle Checkpoint Silencing Requires Association of PP1 to Both Spc7 and Kinesin-8 Motors by Meadows, John C., Shepperd, Lindsey A., Vanoosthuyse, Vincent, Lancaster, Theresa C., Sochaj, Alicja M., Buttrick, Graham J., Hardwick, Kevin G., Millar, Jonathan B.A.

“…The spindle checkpoint is the prime cell-cycle control mechanism that ensures sister chromatids are bioriented before anaphase takes place. Aurora B kinase,…”
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Stable Association of Mitotic Cyclin B/Cdc2 to Replication Origins Prevents Endoreduplication by Wuarin, Jérôme, Buck, Vicky, Nurse, Paul, Millar, Jonathan B.A.

“…We show that in fission yeast the mitotic B type cyclin Cdc13/Cdc2 kinase associates with replication origins in vivo. This association is dependent on the…”
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Plo1 phosphorylates Dam1 to promote chromosome bi-orientation in fission yeast by Buttrick, Graham J, Lancaster, Theresa C, Meadows, John C, Millar, Jonathan B A

“…The fungal-specific heterodecameric outer kinetochore DASH complex facilitates the interaction of kinetochores with spindle microtubules. In budding yeast,…”
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Inactivation of the Cdc25 Phosphatase by the Stress-Activated Srk1 Kinase in Fission Yeast by López-Avilés, Sandra, Grande, Maribel, González, Marta, Helgesen, Ase-Lill, Alemany, Vicenç, Sanchez-Piris, Maribel, Bachs, Oriol, Millar, Jonathan B.A., Aligue, Rosa

“…The mechanisms by which environmental stress regulates cell cycle progression are poorly understood. In fission yeast, we show that Srk1 kinase, which…”
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Sharpening the anaphase switch by Meadows, John C, Millar, Jonathan B A

“…The segregation of sister chromatids during mitosis is one of the most easily visualized, yet most remarkable, events during the life cycle of a cell. The…”
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1406 ORAL Parotid gland sparing in paediatric patients receiving radiotherapy for infratentorial tumours: Optimization of treatment technique to improve normal tissue sparing by Lau, M, Millar, B.A

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Sin1: an evolutionarily conserved component of the eukaryotic SAPK pathway by Wilkinson, M.G, Soto Pino, T, Tournier, S, Buck, V, Martin, H, Christiansen, J, Wilkinson, D.G, Millar, J.B.A

“…The fission yeast Sty1/Spc1 mitogen‐activated protein (MAP) kinase is a member of the eukaryotic stress‐activated MAP kinase (SAPK) family. We have identified…”
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Utilization of Inpatient Radiation Therapy and Spine Surgery during Hospitalization for Metastatic Spinal Cord Compression by Lu, S., Bilgen, I., Shultz, D.B., Wong, P., Dawson, L.A., Wong, R.K., Cummings, B.J., Millar, B.A., Tsai, C.J.

“…Patients with spinal metastases are at risk for malignant spinal cord compression (MSCC), warranting urgent intervention. Early intervention using radiation…”
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Leadership Education in Radiation Oncology Residency Training by Adleman, J., Niglas, M., Millar, B.A.

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