Search Results - "Millan, Christopher"
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PEG/HA Hybrid Hydrogels for Biologically and Mechanically Tailorable Bone Marrow Organoids
Published in Advanced functional materials (01-11-2020)“…Bone marrow (BM) organoids provide powerful tools to study the vital interplay between the BM microenvironment and resident cells. Current biomaterials,…”
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Enhanced bone regeneration in rat calvarial defects through BMP2 release from engineered poly(ethylene glycol) hydrogels
Published in Scientific reports (28-02-2024)“…The clinical standard therapy for large bone defects, typically addressed through autograft or allograft donor tissue, faces significant limitations. Tissue…”
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An Automatable Hydrogel Culture Platform for Evaluating Efficacy of Antibody‐Based Therapeutics in Overcoming Chemoresistance
Published in Biotechnology journal (01-05-2020)“…The microenvironment plays a major role in conferring chemoresistance to cancer cells. In order to better inform clinical response to chemoresistance,…”
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Extracellular Vesicles from 3D Engineered Microtissues Harbor Disease‐Related Cargo Absent in EVs from 2D Cultures
Published in Advanced healthcare materials (01-03-2022)“…Engineered microtissues that recapitulate key properties of the tumor microenvironment can induce clinically relevant cancer phenotypes in vitro. However,…”
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GFOGER-modified MMP-sensitive polyethylene glycol hydrogels induce chondrogenic differentiation of human mesenchymal stem cells
Published in Tissue engineering. Part A (01-04-2014)“…The cellular microenvironment plays a crucial role in directing proliferation and differentiation of stem cells. Cells interact with their microenvironment via…”
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Molecular and biophysical mechanisms regulating hypertrophic differentiation in chondrocytes and mesenchymal stem cells
Published in European cells & materials (24-07-2012)“…Chondrocyte hypertrophy is one of the key physiological processes involved in the longitudinal growth of long bones, yet the regulation of hypertrophy is also…”
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Influence of regular aspirin intake on PSA values, prostate cancer incidence and overall survival in a prospective screening trial (ERSPC Aarau)
Published in World journal of urology (01-10-2020)“…Objectives To analyze the influence of aspirin (ASA) intake on PSA values and prostate cancer (PCa) development in a prospective screening study cohort…”
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3D culture of cancer cells in a polysaccharide-based hydrogel drastically alters the protein and RNA cargo of EVs
Published in Journal of extracellular vesicles (01-01-2018)“…Background: Previously, we have introduced a 3D culture platform based on the polysaccharides chitosan and alginate that confers an altered morphology and…”
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Engineered Microtissues Formed by Schiff Base Crosslinking Restore the Chondrogenic Potential of Aged Mesenchymal Stem Cells
Published in Advanced healthcare materials (01-06-2015)“…A universal method for reproducibly directing stem cell differentiation remains a major challenge for clinical applications involving cell‐based therapies. The…”
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Spatio-temporal analysis of flowering using Li DAR topography
Published in 地理学报:英文版 (2017)“…Spatio-temporal patterns of flowering in forest ecosystems are hard to quantify and monitor. The objectives of this study were to investigate spatio-temporal…”
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Spatio-temporal analysis of flowering using Li DAR topography
Published in 地理学报:英文版 (2017)“…Spatio-temporal patterns of flowering in forest ecosystems are hard to quantify and monitor. The objectives of this study were to investigate spatio-temporal…”
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