Search Results - "Milker, Sofia"

First time β-farnesene production by the versatile bacterium Cupriavidus necator by Milker, Sofia, Holtmann, Dirk

“…Terpenes are remarkably diverse natural structures, which can be formed via two different pathways leading to two common intermediates. Among those,…”
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Biomass pretreatment affects Ustilago maydis in producing itaconic acid by Klement, Tobias, Milker, Sofia, Jäger, Gernot, Grande, Philipp M, Domínguez de María, Pablo, Büchs, Jochen

“…In the last years, the biotechnological production of platform chemicals for fuel components has become a major focus of interest. Although ligno-cellulosic…”
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Escherichia coli Fails to Efficiently Maintain the Activity of an Important Flavin Monooxygenase in Recombinant Overexpression by Milker, Sofia, Goncalves, Leticia C P, Fink, Michael J, Rudroff, Florian

“…This paper describes the measurement and analysis of activity and stability of cyclohexanone monooxygenase from sp. NCIMB 9871 (CHMO), a model Baeyer-Villiger…”
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Knallgasbakterien – neue Synthesewege mit Cupriavidus necator by Milker, Sofia, Kunze, Cindy, Sydow, Anne, Kroner, Cora, Holtmann, Dirk

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First time [beta]-farnesene production by the versatile bacterium Cupriavidus necator by Milker, Sofia, Holtmann, Dirk

“…Terpenes are remarkably diverse natural structures, which can be formed via two different pathways leading to two common intermediates. Among those,…”
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Identification of vitamin B12 producing bacteria based on the presence of bluB/cobT2 homologues by Dudko, Darya, Milker, Sofia, Holtmann, Dirk, Buchhaupt, Markus

“…Objectives The objective of the study was to develop a strategy for the identification of new vitamin B 12 -producing species and to characterize their…”
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Gram‐scale production of the sesquiterpene α‐humulene with Cupriavidus necator by Milker, Sofia, Sydow, Anne, Torres‐Monroy, Ingrid, Jach, Guido, Faust, Frederik, Kranz, Lea, Tkatschuk, Ljubov, Holtmann, Dirk

“…Terpenoids have an impressive structural diversity and provide valuable substances for a variety of industrial applications. Among terpenes, the sesquiterpenes…”
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Designer Microorganisms for Optimized Redox Cascade Reactions - Challenges and Future Perspectives by Bayer, Thomas, Milker, Sofia, Wiesinger, Thomas, Rudroff, Florian, Mihovilovic, Marko. D.

“…An immense number of chemical reactions are carried out simultaneously in living cells. Nature’s optimization approach encompasses the assembly of reactions in…”
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Identification of vitamin B 12 producing bacteria based on the presence of bluB/cobT2 homologues by Dudko, Darya, Milker, Sofia, Holtmann, Dirk, Buchhaupt, Markus

“…The objective of the study was to develop a strategy for the identification of new vitamin B -producing species and to characterize their production capability…”
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Non‐hazardous biocatalytic oxidation in Nylon‐9 monomer synthesis on a 40g scale with efficient downstream processing by Milker, Sofia, Fink, Michael J, Rudroff, Florian, Mihovilovic, Marko D

“…This paper describes the development of a biocatalytic process on the multi‐dozen gram scale for the synthesis of a precursor to Nylon‐9, a specialty…”
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Non‐hazardous biocatalytic oxidation in Nylon‐9 monomer synthesis on a 40 g scale with efficient downstream processing by Milker, Sofia, Fink, Michael J., Rudroff, Florian, Mihovilovic, Marko D.

“…ABSTRACT This paper describes the development of a biocatalytic process on the multi‐dozen gram scale for the synthesis of a precursor to Nylon‐9, a specialty…”
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In Vivo Synthesis of Polyhydroxylated Compounds from a “Hidden Reservoir” of Toxic Aldehyde Species by Bayer, Thomas, Milker, Sofia, Wiesinger, Thomas, Winkler, Margit, Mihovilovic, Marko D., Rudroff, Florian

“…Synthetic enzyme cascades in living cells often lack efficiency owing to the formation of byproducts by endogenous enzymes or toxicity of the cascade…”
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Kinetic Modeling of an Enzymatic Redox Cascade In Vivo Reveals Bottlenecks Caused by Cofactors by Milker, Sofia, Fink, Michael J., Oberleitner, Nikolin, Ressmann, Anna K., Bornscheuer, Uwe T., Mihovilovic, Marko D., Rudroff, Florian

“…We describe the development of a kinetic model for the simulation and optimization of an in vivo redox cascade in E. coli in which a combination of an alcohol…”
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Cell Factory Design and Optimization for the Stereoselective Synthesis of Polyhydroxylated Compounds by Wiesinger, Thomas, Bayer, Thomas, Milker, Sofia, Mihovilovic, Marko D., Rudroff, Florian

“…A synthetic cascade for the transformation of primary alcohols into polyhydroxylated compounds in Escherichia coli, through the in situ preparation of…”
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Mutagenesis‐Independent Stabilization of Class B Flavin Monooxygenases in Operation by Goncalves, Leticia C. P., Kracher, Daniel, Milker, Sofia, Fink, Michael J., Rudroff, Florian, Ludwig, Roland, Bommarius, Andreas S., Mihovilovic, Marko D.

“…This paper describes the stabilization of flavin‐dependent monooxygenases under reaction conditions, using an engineered formulation of additives (the natural…”
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Front Cover: Cell Factory Design and Optimization for the Stereoselective Synthesis of Polyhydroxylated Compounds (ChemBioChem 4/2018) by Wiesinger, Thomas, Bayer, Thomas, Milker, Sofia, Mihovilovic, Marko D., Rudroff, Florian

“…The front cover picture shows an artificial metabolic mini‐pathway composed of an alcohol dehydrogenase and a dihydroxyacetone‐dependent aldolase for the…”
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Kinetic Modeling of an Enzymatic Redox Cascade InVivo Reveals Bottlenecks Caused by Cofactors by Milker, Sofia, Fink, Michael J, Oberleitner, Nikolin, Ressmann, Anna K, Bornscheuer, Uwe T, Mihovilovic, Marko D, Rudroff, Florian

“…We describe the development of a kinetic model for the simulation and optimization of an invivo redox cascade in E.coli in which a combination of an alcohol…”
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Back Cover: In Vivo Synthesis of Polyhydroxylated Compounds from a “Hidden Reservoir” of Toxic Aldehyde Species (ChemCatChem 15/2017) by Bayer, Thomas, Milker, Sofia, Wiesinger, Thomas, Winkler, Margit, Mihovilovic, Marko D., Rudroff, Florian

“…The Cover shows a biochemical cell factory (Escherichia coli) for the synthesis of chiral polyhydroxylated compounds via an artificial enzyme cascade.In their…”
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InVivo Synthesis of Polyhydroxylated Compounds from a "Hidden Reservoir" of Toxic Aldehyde Species by Bayer, Thomas, Milker, Sofia, Wiesinger, Thomas, Winkler, Margit, Mihovilovic, Marko D, Rudroff, Florian

“…Synthetic enzyme cascades in living cells often lack efficiency owing to the formation of byproducts by endogenous enzymes or toxicity of the cascade…”
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Back Cover: InVivo Synthesis of Polyhydroxylated Compounds from a "Hidden Reservoir" of Toxic Aldehyde Species by Bayer, Thomas, Milker, Sofia, Wiesinger, Thomas, Winkler, Margit, Mihovilovic, Marko D, Rudroff, Florian

“…The Cover shows a biochemical cell factory (Escherichia coli) for the synthesis of chiral polyhydroxylated compounds via an artificial enzyme cascade.In their…”
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