Search Results - "Miljković, Đorđe"
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Ethyl pyruvate, a versatile protector in inflammation and autoimmunity
Published in Inflammation research (01-02-2022)“…Ethyl pyruvate (EP) has potent influence on redox processes, cellular metabolism, and inflammation. It has been intensively studied in numerous animal models…”
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2
ILC3, a Central Innate Immune Component of the Gut-Brain Axis in Multiple Sclerosis
Published in Frontiers in immunology (12-04-2021)“…Gut immune cells have been increasingly appreciated as important players in the central nervous system (CNS) autoimmunity in animal models of multiple…”
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Complete Freund's adjuvant as a confounding factor in multiple sclerosis research
Published in Frontiers in immunology (15-02-2024)“…Complete Freund's adjuvant (CFA) is used as a standard adjuvant for the induction of experimental autoimmune encephalomyelitis (EAE), the most commonly used…”
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4
NRF2 Plays a Crucial Role in the Tolerogenic Effect of Ethyl Pyruvate on Dendritic Cells
Published in International journal of molecular sciences (01-06-2024)“…Ethyl pyruvate (EP) is a redox-active compound that has been previously shown to be effective in restraining immune hyperactivity in animal models of various…”
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5
Modulation of Intestinal ILC3 for the Treatment of Type 1 Diabetes
Published in Frontiers in immunology (03-06-2021)“…Gut-associated lymphoid tissue (GALT) is crucial for the maintenance of the intestinal homeostasis, but it is also the potential site of the activation of…”
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6
Anti-Neuroinflammatory Effects of a Novel Bile Acid Derivative
Published in International journal of molecular sciences (28-06-2024)“…In the search for novel potent immunomodulatory nuclear factor-erythroid 2 related factor 2 (Nrf2) activators, a derivative of cholic bile acid, SB140, was…”
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7
ILC3: a case of conflicted identity
Published in Frontiers in immunology (17-10-2023)“…Innate lymphoid cells type 3 (ILC3s) are the first line sentinels at the mucous tissues, where they contribute to the homeostatic immune response in a major…”
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8
Gut Microbiota Confers Resistance of Albino Oxford Rats to the Induction of Experimental Autoimmune Encephalomyelitis
Published in Frontiers in immunology (02-05-2018)“…Albino Oxford (AO) rats are extremely resistant to induction of experimental autoimmune encephalomyelitis (EAE). EAE is an animal model of multiple sclerosis,…”
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Benfotiamine Reduces Dendritic Cell Inflammatory Potency
Published in Endocrine, metabolic & immune disorders drug targets (01-01-2021)“…Benfotiamine is a synthetic liposoluble derivative of vitamin B1 that has been shown to have anti-inflammatory properties. To study the effects of benfotiamine…”
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10
Ethyl pyruvate ameliorates acute respiratory distress syndrome in mice
Published in European journal of pharmacology (15-05-2024)“…Acute respiratory distress syndrome (ARDS) became a focus of intensive research due to its death toll during the Covid-19 pandemic. An uncontrolled and…”
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Oral neonatal antibiotic treatment perturbs gut microbiota and aggravates central nervous system autoimmunity in Dark Agouti rats
Published in Scientific reports (29-01-2019)“…Gut microbiota dysbiosis has been considered the essential element in the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune…”
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12
Phenethyl Ester of Gallic Acid Ameliorates Experimental Autoimmune Encephalomyelitis
Published in Molecules (Basel, Switzerland) (01-12-2022)“…Gallic acid is a phenolic acid present in various plants, nuts, and fruits. It is well known for its anti-oxidative and anti-inflammatory properties. The…”
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13
The H₂S Donor GYY4137 Stimulates Reactive Oxygen Species Generation in BV2 Cells While Suppressing the Secretion of TNF and Nitric Oxide
Published in Molecules (Basel, Switzerland) (14-11-2018)“…GYY4137 is a hydrogen sulfide (H₂S) donor that has been shown to act in an anti-inflammatory manner in vitro and in vivo. Microglial cells are among the major…”
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Increased regulatory activity of intestinal innate lymphoid cells type 3 (ILC3) prevents experimental autoimmune encephalomyelitis severity
Published in Journal of neuroinflammation (18-01-2024)“…Experimental autoimmune encephalomyelitis (EAE) induced in inbred rodents, i.e., genetically identical animals kept under identical environmental conditions,…”
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Ethyl Pyruvate Ameliorates Experimental Autoimmune Myocarditis
Published in Biomolecules (Basel, Switzerland) (25-11-2021)“…Ethyl pyruvate (EP) has profound anti-inflammatory and immunomodulatory properties. Here, its effects were determined on experimental autoimmune myocarditis…”
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MIF and insulin: Lifetime companions from common genesis to common pathogenesis
Published in Cytokine (Philadelphia, Pa.) (01-01-2020)“…•MIF is a cytokine, chemokine, enzyme, chaperone and a hormone.•MIF is essential for proper insulin conformation in pancreatic beta cells.•By stimulating…”
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Brain inflammation in experimental autoimmune encephalomyelitis induced in Dark Agouti rats with spinal cord homogenate
Published in Immunology letters (01-06-2024)“…•EAE was induced in DA rats with spinal cord homogenate without adjuvant.•Reactivity of T and B cells to MBP, MOG, and β-synuclein was detected.•T cell…”
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Pomegranate peel extract ameliorates autoimmunity in animal models of multiple sclerosis and type 1 diabetes
Published in Journal of functional foods (01-08-2017)“…•Pomegranate peel extract is rich in punicalin, punicalagin and ellagic acid.•Pomegranate peel extract ameliorates experimental autoimmune…”
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Sepsis and multiple sclerosis: Causative links and outcomes
Published in Immunology letters (01-10-2021)“…•Potential interplay between sepsis and multiple sclerosis (MS) is reviewed.•Immunological mechanism(s) governing sepsis/MS interactions are proposed.•The role…”
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Complete Freund's adjuvant-free experimental autoimmune encephalomyelitis in Dark Agouti rats is a valuable tool for multiple sclerosis studies
Published in Journal of neuroimmunology (15-05-2021)“…Experimental autoimmune encephalomyelitis (EAE) is classically induced with complete Freund's adjuvant (CFA). The immune response against CFA has a confounding…”
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