Search Results - "Militao, Gardenia C G"

Characterization of the biochemical, physiological, and medicinal properties of Streptomyces hygroscopicus ACTMS-9H isolated from the Amazon (Brazil) by Lima, Sandrine M. A., Melo, Janaína. G. S., Militão, Gardênia C. G., Lima, Gláucia M. S., do Carmo A. Lima, Maria, Aguiar, Jaciana S., Araújo, Renata M., Braz-Filho, Raimundo, Marchand, Pascal, Araújo, Janete M., Silva, Teresinha G.

“…Actinomycetes are known to produce numerous secondary bioactive metabolites of pharmaceutical interest. The purpose of this study was to isolate, characterize,…”
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New Cytotoxic Bibenzyl and Other Constituents from Bauhinia ungulata L. (Fabaceae) by de Sousa, Leôncio M., de Carvalho, Jarbas L., da Silva, Horlando C., Lemos, Telma L. G., Arriaga, Angela M. C., Braz-Filho, Raimundo, Militão, Gardênia C. G., Silva, Thiago D. S., Ribeiro, Paulo R. V., Santiago, Gilvandete M. P.

“…A new bibenzyl, 2′‐hydroxy‐3,5‐dimethoxy‐4‐methylbibenzyl (1) and four known compounds identified as 2′‐hydroxy‐3,5‐dimethoxybibenzyl (2), liquiritigenin (3),…”
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Pterocarpanquinones, aza-pterocarpanquinone and derivatives: Synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis by Buarque, Camilla D., Militão, Gardenia C.G., Lima, Daisy J.B., Costa-Lotufo, Leticia V., Pessoa, Cláudia, de Moraes, Manoel Odorico, Cunha-Junior, Edézio Ferreira, Torres-Santos, Eduardo Caio, Netto, Chaquip D., Costa, Paulo R.R.

“…Pterocarpanquinones (1a–e) and the aza-pterocarpanquinone (2) were synthesized through palladium catalyzed oxyarylation and azaarylation of conjugate olefins,…”
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Chemical Composition, Leishmanicidal and Cytotoxic Activities of the Essential Oils from Mangifera indica L. var. Rosa and Espada by Ramos, Eduardo H. S., Moraes, Marcílio M., Nerys, Laís L. de A., Nascimento, Silene Carneiro do, Militão, Gardenia Carmen Gadelha, Figueiredo, Regina Célia Bressan Queiroz, da Câmara, Cláudio A. G., da Silva, Teresinha Gonçalves

“…The essential oils from Mangifera indica var. Rosa and Espada latex were obtained by hydrodistillation and analyzed using GC-FID and GC-MS. Twenty-seven…”
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Cyclohexene-fused 1,3-oxazines with selective antibacterial and antiparasitic action and low cytotoxic effects by de Brito, Maria R.M., Peláez, Walter J., Faillace, Martín S., Militão, Gardenia C.G., Almeida, Jackson R.G.S., Argüello, Gustavo A., Szakonyi, Zsolt, Fülöp, Ferenc, Salvadori, Maria C., Teixeira, Fernanda S., Freitas, Rivelilson M., Pinto, Pedro L.S., Mengarda, Ana C., Silva, Marcos P.N., Da Silva Filho, Ademar A., de Moraes, Josué

“…Oxazine derivatives, a class of heterocyclic compounds, exhibit a variety of biological properties, such as anticonvulsant and antitumor activities. In this…”
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N-pentyl-nitrofurantoin induces apoptosis in HL-60 leukemia cell line by upregulating BAX and downregulating BCL-xL gene expression by Andrade, Jeyce K F, Souza, Márcia I F, Gomes Filho, Manoel A, Silva, Diogo M F, Barros, André L S, Rodrigues, Maria D, Silva, Paulo B N, Nascimento, Silene C, Aguiar, Jaciana S, Brondani, Dalci J, Militão, Gardênia C G, Silva, Teresinha G

“…Nitrofurantoin is a nitroderivative antibiotic that has bactericidal activity against pathogens causing urinary tract infection. A few studies have reported…”
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Comparative cytotoxicity of 2,3,9-trimethoxypterocarpan in leukemia cell lines (HL-60, Jurkat, Molt-4, and K562) and human peripheral blood mononuclear cells by Militão, Gardenia C. G, Bezerra, Daniel P, Pessoa, Claudia, de Moraes, Manoel Odorico, da Ponte, Flavio A. F, Lima, Mary Anne S, Silveira, Edilberto R, Costa-Lotufo, Letícia V

“…The purpose of this study was to investigate the antiproliferative activity of 2,3,9-trimethoxypterocarpan, a known pterocarpan with cytotoxic activity against…”
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In vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa by Militão, Gardenia C G, Dantas, Ivana N F, Ferreira, Paulo Michel P, Alves, Ana Paula N N, Chaves, Davina C, Monte, Francisco José Q, Pessoa, Cláudia, Odorico de Moraes, Manoel, Costa-Lotufo, Letícia V

“…Cucurbitacins are a group of triterpenoids that have a cucurbitane skeleton with a wide range of biological activities. This study evaluated the anticancer…”
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Development and characterization of a novel flavopiridol formulation for treatment of acute myeloid leukemia by Chen, Kent T.J., Militao, Gardenia G.C., Anantha, Malathi, Witzigmann, Dominik, Leung, Ada W.Y., Bally, Marcel B.

“…For more than 30 years, treatment of acute myeloid leukemia (AML) has remained largely unchanged and reliant on chemotherapeutic drug combinations,…”
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Cytotoxic and leishmanicidal properties of garcinielliptone FC, a prenylated benzophenone from Platonia insignis by Costa Júnior, Joaquim S., de Almeida, Antonia Amanda Cardoso, Ferraz, Alexandre de Barros Falcão, Rossatto, Raíssa Rebés, Silva, Teresinha G., Silva, Paulo B.N., Militão, Gardenia C.G., Citó, Antonia Maria das Graças Lopes, Santana, Lorena Citó Lopes Resende, Carvalho, Fernando Aécio de Amorim, Freitas, Rivelilson M.

“…Garcinielliptone FC (GFC), a natural prenylated benzophenone, was extracted from Platonia insignis Mart. (Clusiaceae), a native plant commonly known as bacuri…”
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Bioassay-guided fractionation of pterocarpans from roots of Harpalyce brasiliana Benth by Militão, Gardenia C.G., Pinheiro, Sávio M., Dantas, Ivana N.F., Pessoa, Cláudia, de Moraes, Manoel Odorico, Costa-Lotufo, Letı´cia V., Lima, Mary Anne S., Silveira, Edilberto R.

“…A bioassay-guided fractionation of antimitotic pterocarpans present in the EtOH extract from the roots of Harpalyce brasiliana. Some initial studies on…”
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Synthesis and preliminary evaluation of 3-thiocyanato-1H-indoles as potential anticancer agents by Fortes, Margiani P., da Silva, Paulo B.N., da Silva, Teresinha G., Kaufman, Teodoro S., Militão, Gardenia C.G., Silveira, Claudio C.

“…A novel series of twenty 3-thiocyanato-1H-indoles, carrying diversification at positions N-1, C-2 and C-5 of the heterocyclic core, were synthesized; their…”
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Induction of cancer cell death by apoptosis and slow release of 5-fluoracil from metal-organic frameworks Cu-BTC by Lucena, Flávia Raquel Santos, de Araújo, Larissa C.C, Rodrigues, Maria do D, da Silva, Teresinha G, Pereira, Valéria R.A, Militão, Gardênia C.G, Fontes, Danilo A.F, Rolim-Neto, Pedro J, da Silva, Fausthon F, Nascimento, Silene C

“…Abstract This study aimed to evaluate the mechanism associated with cytotoxic activity displayed by the drug 5-fluorouracil incorporated in Cu-BTC MOF and its…”
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Characterization of a liposomal copper(II)-quercetin formulation suitable for parenteral use by Chen, Kent T. J., Anantha, Malathi, Leung, Ada W. Y., Kulkarni, Jayesh A., Militao, Gardenia G. C., Wehbe, Mohamed, Sutherland, Brent, Cullis, Pieter R., Bally, Marcel B.

“…Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is a naturally derived flavonoid that is commonly found in fruits and vegetables. There is mounting evidence to…”
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Synthesis and Anticancer Activity of Homodimeric Morita-Baylis-Hillman Adducts Based on 3-Hydroxyindolin-2-one Core by Coelho, Maísa, Castro, Aleff, Olegário, Tayná, Cristiano, Rodrigo, Vaz, Boniek, dos Santos, Gabriel, Machado, Lucas, Militão, Gardênia, da Silva, Paulo, Vasconcellos, Mário, Lima-Junior, Claudio

“…Cancer treatment represents one of the main scientific study targets today, mainly due to the pronounced side effects arising from chemotherapy. This study…”
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Chemical composition and biological activities of the essential oils from Vitex-agnus castus, Ocimum campechianum and Ocimum carnosum by Ricarte, Lara P, Bezerra, Gabrieli P, Romero, Nirla R, Silva, Horlando C DA, Lemos, Telma L G, Arriaga, Angela M C, Alves, Péricles B, Santos, Marcelo B Dos, Militão, Gardenia C G, Silva, Thiago D S, Braz-Filho, Raimundo, Santiago, Gilvandete M P

“…The essential oils obtained by hydrodistillation from fresh leaves of Vitex agnus-castus and Ocimum campechianum, and from fresh inflorescences of Ocimum…”
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Synthesis and evaluation of (−)-Massoialactone and analogues as potential anticancer and anti-inflammatory agents by Barros, Maria E.S.B., Freitas, Juliano C.R., Oliveira, Juliana M., da Cruz, Carlos H.B., da Silva, Paulo B.N., de Araújo, Larissa C.C., Militão, Gardenia C.G., da Silva, Teresinha G., Oliveira, Roberta A., Menezes, Paulo H.

“…(−)-Massoialactone, an α,β-unsaturated δ-lactone isolated from Cryptocarya massoia, and five analogues were synthesized and their antiproliferative and…”
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Morita-Baylis-Hillman Reaction with 7-Chloroquinoline Derivatives‑New Compounds with Potential Anticancer Activity by Oliveira, João Paulo, Caleffi, Guilherme, Silva, Everton, Coelho, Maísa, Castro, Aleff, Mendes, Rhuan, Olegário, Tayná, Lima-Junior, Claudio, Vasconcellos, Mario, Souza, Júlia, Souza, Sílvia, Militão, Gardênia, Vaz, Boniek, Ramalho, Ruver

“…Morita-Baylis-Hillman adducts (MBHA) is a class of polyfunctional molecules that has been standing out due to their versatility and expressive biological…”
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Structure-based design, synthesis and antitumoral evaluation of enulosides by Santos, Jonh A.M., Santos, Cosme S., Almeida, Claudia L.A., Silva, Thiago D.S., Freitas Filho, João R., Militão, Gardenia C.G., da Silva, Teresinha G., da Cruz, Carlos H.B., Freitas, Juliano C.R., Menezes, Paulo H.

“…Enulosides, carbohydrate derivatives containing an α,β-unsaturated carbonyl unit, were designed and obtained in high yields and isomeric purity. All…”
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Selective cytotoxic and genotoxic activities of 5-(2-bromo-5-methoxybenzylidene)-thiazolidine-2,4-dione against NCI-H292 human lung carcinoma cells by Rodrigues, Maria do D, Santiago, Priscila B G S, Marques, Karla M R, Pereira, Valéria R A, de Castro, Maria C A B, Cantalice, Jeanne C L L, da Silva, Teresinha G, Adam, Mônica L, do Nascimento, Silene C, de Albuquerque, Julianna F C, Militao, Gardenia C G

“…Thiazolidine-2,4-dione ring system is used as a pharmacophore to build various heterocyclic compounds aimed to interact with biological targets. In the present…”
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