Search Results - "Milind, Mahajan"

Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency by Liang, Raymond, Arif, Tasleem, Kalmykova, Svetlana, Kasianov, Artem, Lin, Miao, Menon, Vijay, Qiu, Jiajing, Bernitz, Jeffrey M., Moore, Kateri, Lin, Fangming, Benson, Deanna L., Tzavaras, Nikolaos, Mahajan, Milind, Papatsenko, Dmitri, Ghaffari, Saghi

“…Quiescence is a fundamental property that maintains hematopoietic stem cell (HSC) potency throughout life. Quiescent HSCs are thought to rely on glycolysis for…”
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De novo mutations in schizophrenia implicate synaptic networks by Fromer, Menachem, Pocklington, Andrew J., Kavanagh, David H., Williams, Hywel J., Dwyer, Sarah, Gormley, Padhraig, Georgieva, Lyudmila, Rees, Elliott, Palta, Priit, Ruderfer, Douglas M., Carrera, Noa, Humphreys, Isla, Johnson, Jessica S., Roussos, Panos, Barker, Douglas D., Banks, Eric, Milanova, Vihra, Grant, Seth G., Hannon, Eilis, Rose, Samuel A., Chambert, Kimberly, Mahajan, Milind, Scolnick, Edward M., Moran, Jennifer L., Kirov, George, Palotie, Aarno, McCarroll, Steven A., Holmans, Peter, Sklar, Pamela, Owen, Michael J., Purcell, Shaun M., O’Donovan, Michael C.

“…Inherited alleles account for most of the genetic risk for schizophrenia. However, new ( de novo ) mutations, in the form of large chromosomal copy number…”
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Nanoemulsion-based intranasal drug delivery system of saquinavir mesylate for brain targeting by Mahajan, Hitendra S, Mahajan, Milind S, Nerkar, Pankaj P, Agrawal, Anshuman

“…The central nervous system (CNS) is an immunological privileged sanctuary site-providing reservoir for HIV-1 virus. Current anti-HIV drugs, although effective…”
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Whole-Exome Sequencing (WES) for Illumina Short Read Sequencers Using Solution-Based Capture by Mahajan, Milind C, McLellan, Andrew S

“…Next-generation sequencing (NGS) is transforming clinical research and diagnostics, vastly enhancing our ability to identify novel disease-causing genetic…”
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Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition by Nakagawa, Shigeki, Wei, Lan, Song, Won Min, Higashi, Takaaki, Ghoshal, Sarani, Kim, Rosa S., Bian, C. Billie, Yamada, Suguru, Sun, Xiaochen, Venkatesh, Anu, Goossens, Nicolas, Bain, Gretchen, Lauwers, Gregory Y., Koh, Anna P., El-Abtah, Mohamed, Ahmad, Noor B., Hoshida, Hiroki, Erstad, Derek J., Gunasekaran, Ganesh, Lee, Youngmin, Yu, Ming-Lung, Chuang, Wan-Long, Dai, Chia-Yen, Kobayashi, Masahiro, Kumada, Hiromitsu, Beppu, Toru, Baba, Hideo, Mahajan, Milind, Nair, Venugopalan D., Lanuti, Michael, Villanueva, Augusto, Sangiovanni, Angelo, Iavarone, Massimo, Colombo, Massimo, Llovet, Josep M., Subramanian, Aravind, Tager, Andrew M., Friedman, Scott L., Baumert, Thomas F., Schwarz, Myron E., Chung, Raymond T., Tanabe, Kenneth K., Zhang, Bin, Fuchs, Bryan C., Hoshida, Yujin

“…Cirrhosis is a milieu that develops hepatocellular carcinoma (HCC), the second most lethal cancer worldwide. HCC prediction and prevention in cirrhosis are key…”
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Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity by van Hasselt, J. G. Coen, Rahman, Rayees, Hansen, Jens, Stern, Alan, Shim, Jaehee V., Xiong, Yuguang, Pickard, Amanda, Jayaraman, Gomathi, Hu, Bin, Mahajan, Milind, Gallo, James M., Goldfarb, Joseph, Sobie, Eric A., Birtwistle, Marc R., Schlessinger, Avner, Azeloglu, Evren U., Iyengar, Ravi

“…Kinase inhibitors (KIs) represent an important class of anti-cancer drugs. Although cardiotoxicity is a serious adverse event associated with several KIs, the…”
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Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing by Fang, Gang, Munera, Diana, Friedman, David I, Mandlik, Anjali, Chao, Michael C, Banerjee, Onureena, Feng, Zhixing, Losic, Bojan, Mahajan, Milind C, Jabado, Omar J, Deikus, Gintaras, Clark, Tyson A, Luong, Khai, Murray, Iain A, Davis, Brigid M, Keren-Paz, Alona, Chess, Andrew, Roberts, Richard J, Korlach, Jonas, Turner, Steve W, Kumar, Vipin, Waldor, Matthew K, Schadt, Eric E

“…Fang et al . generate the first genome-wide, strand-specific, single base–pair resolution map of m6A modifications in Escherichia coli . Single-molecule…”
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Ultrawide band cage dipole antenna for ultra high frequency band ground penetrating radar system by Kumar, Gaurav, Mevada, Pratik, Chakrabarty, Soumyabrata, Mahajan, Milind B.

“…This paper presents ultrawide band (UWB) Cage Dipole Antenna, designed and developed for ultra high frequency band ground penetrating radar (GPR) system. The…”
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A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma by Labgaa, Ismail, Villacorta-Martin, Carlos, D’Avola, Delia, Craig, Amanda J., von Felden, Johann, Martins-Filho, Sebastiao N., Sia, Daniela, Stueck, Ashley, Ward, Stephen C., Fiel, M. Isabel, Mahajan, Milind, Tabrizian, Parissa, Thung, Swan N., Ang, Celina, Friedman, Scott L., Llovet, Josep M., Schwartz, Myron, Villanueva, Augusto

“…Cellular components of solid tumors including DNA are released into the bloodstream, but data on circulating-free DNA (cfDNA) in hepatocellular carcinoma (HCC)…”
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The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease by Wang, Minghui, Beckmann, Noam D., Roussos, Panos, Wang, Erming, Zhou, Xianxiao, Wang, Qian, Ming, Chen, Neff, Ryan, Ma, Weiping, Fullard, John F., Hauberg, Mads E., Bendl, Jaroslav, Peters, Mette A., Logsdon, Ben, Wang, Pei, Mahajan, Milind, Mangravite, Lara M., Dammer, Eric B., Duong, Duc M., Lah, James J., Seyfried, Nicholas T., Levey, Allan I., Buxbaum, Joseph D., Ehrlich, Michelle, Gandy, Sam, Katsel, Pavel, Haroutunian, Vahram, Schadt, Eric, Zhang, Bin

“…Alzheimer’s disease (AD) affects half the US population over the age of 85 and is universally fatal following an average course of 10 years of progressive…”
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Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas by Wang, Huan, Bender, Aaron, Wang, Peng, Karakose, Esra, Inabnet, William B., Libutti, Steven K., Arnold, Andrew, Lambertini, Luca, Stang, Micheal, Chen, Herbert, Kasai, Yumi, Mahajan, Milind, Kinoshita, Yayoi, Fernandez-Ranvier, Gustavo, Becker, Thomas C., Takane, Karen K., Walker, Laura A., Saul, Shira, Chen, Rong, Scott, Donald K., Ferrer, Jorge, Antipin, Yevgeniy, Donovan, Michael, Uzilov, Andrew V., Reva, Boris, Schadt, Eric E., Losic, Bojan, Argmann, Carmen, Stewart, Andrew F.

“…Although diabetes results in part from a deficiency of normal pancreatic beta cells, inducing human beta cells to regenerate is difficult. Reasoning that…”
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A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery by Crouchet, Emilie, Bandiera, Simonetta, Fujiwara, Naoto, Li, Shen, El Saghire, Hussein, Fernández-Vaquero, Mirian, Riedl, Tobias, Sun, Xiaochen, Hirschfield, Hadassa, Jühling, Frank, Zhu, Shijia, Roehlen, Natascha, Ponsolles, Clara, Heydmann, Laura, Saviano, Antonio, Qian, Tongqi, Venkatesh, Anu, Lupberger, Joachim, Verrier, Eloi R., Sojoodi, Mozhdeh, Oudot, Marine A., Duong, François H. T., Masia, Ricard, Wei, Lan, Thumann, Christine, Durand, Sarah C., González-Motos, Victor, Heide, Danijela, Hetzer, Jenny, Nakagawa, Shigeki, Ono, Atsushi, Song, Won-Min, Higashi, Takaaki, Sanchez, Roberto, Kim, Rosa S., Bian, C. Billie, Kiani, Karun, Croonenborghs, Tom, Subramanian, Aravind, Chung, Raymond T., Straub, Beate K., Schuppan, Detlef, Ankavay, Maliki, Cocquerel, Laurence, Schaeffer, Evelyne, Goossens, Nicolas, Koh, Anna P., Mahajan, Milind, Nair, Venugopalan D., Gunasekaran, Ganesh, Schwartz, Myron E., Bardeesy, Nabeel, Shalek, Alex K., Rozenblatt-Rosen, Orit, Regev, Aviv, Felli, Emanuele, Pessaux, Patrick, Tanabe, Kenneth K., Heikenwälder, Mathias, Schuster, Catherine, Pochet, Nathalie, Zeisel, Mirjam B., Fuchs, Bryan C., Hoshida, Yujin, Baumert, Thomas F.

“…Chronic liver disease and hepatocellular carcinoma (HCC) are life-threatening diseases with limited treatment options. The lack of clinically…”
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A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1 by Wontakal, Sandeep N, Guo, Xingyi, Will, Britta, Shi, Minyi, Raha, Debasish, Mahajan, Milind C, Weissman, Sherman, Snyder, Michael, Steidl, Ulrich, Zheng, Deyou, Skoultchi, Arthur I

“…PU.1 is a hematopoietic transcription factor that is required for the development of myeloid and B cells. PU.1 is also expressed in erythroid progenitors,…”
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Comparison of interpolation algorithms to transform polar grid to rectangular grid in plane polar near field antenna test range by Kumar, Rakesh, Mevada, Pratik, Kulshrestha, Sanjeev, Chakrabarty, Soumyabrata, Mahajan, Milind B.

“…This paper addresses the implementation of various interpolation algorithms to transform the measured near field (NF) polar grid data into rectangular grid…”
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Miniaturized Quad-Port Conformal Multi-Band (QPC-MB) MIMO Antenna for On-Body Wireless Systems in Microwave-Millimeter Bands by Sharma, Manish, Kapula, Prabhakara Rao, Salagrama, Shailaja, Sharma, Kanhaiya, Pandey, Ganga Prasad, Singh, Dinesh Kumar, Mahajan, Milind, Gupta, Anupma

“…In this endeavor, miniaturized quad-port MIMOMB (multiple-input-multiple-output multi-band) antenna with an overall area of 400 mm2 offering…”
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Clinicopathological indices to predict hepatocellular carcinoma molecular classification by Tan, Poh Seng, Nakagawa, Shigeki, Goossens, Nicolas, Venkatesh, Anu, Huang, Tiangui, Ward, Stephen C., Sun, Xiaochen, Song, Won-Min, Koh, Anna, Canasto-Chibuque, Claudia, Deshmukh, Manjeet, Nair, Venugopalan, Mahajan, Milind, Zhang, Bin, Fiel, Maria Isabel, Kobayashi, Masahiro, Kumada, Hiromitsu, Hoshida, Yujin

“…Background & Aims Hepatocellular carcinoma (HCC) is the second most lethal cancer caused by lack of effective therapies. Although promising, HCC molecular…”
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Compact high-gain composite horn antenna for space-borne beacon application by Gupta, Ramesh Chandra, Mahajan, Milind Bhagwan-rao, Jyoti, Rajeev

“…The growing interest in higher capacity communications satellite necessitates the development of compact and lightweight other antennas (such as beacon horn…”
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Intracoronary Imaging, Cholesterol Efflux, and Transcriptomes after Intensive Statin Treatment: The YELLOW II study by Kini, Annapoorna S., MD, Vengrenyuk, Yuliya, PhD, Shameer, Khader, PhD, Maehara, Akiko, MD, Purushothaman, Meerarani, PhD, Yoshimura, Takahiro, MD, Matsumura, Mitsuaki, BS, Aquino, Melissa, MS, Haider, Nezam, PhD, Johnson, Kipp W., BS, Readhead, Ben, MBBS, Kidd, Brian A., PhD, Feig, Jonathan E., MD, PhD, Krishnan, Prakash, MD, Sweeny, Joseph, MD, Mahajan, Milind, PhD, Moreno, Pedro, MD, Mehran, Roxana, MD, Kovacic, Jason C., MD, PhD, Baber, Usman, MD, Dudley, Joel T., PhD, Narula, Jagat, MD, PhD, Sharma, Samin, MD

“…Abstract Background Despite the extensive evidence for the beneficial effects of statins on clinical outcomes, the mechanisms underlying these effects in…”
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Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells by Shabman, Reed S, Jabado, Omar J, Mire, Chad E, Stockwell, Timothy B, Edwards, Megan, Mahajan, Milind, Geisbert, Thomas W, Basler, Christopher F

“…Deep sequencing of RNAs produced by Zaire ebolavirus (EBOV) or the Angola strain of Marburgvirus (MARV-Ang) identified novel viral and cellular mechanisms that…”
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Analytical validation of whole exome and whole genome sequencing for clinical applications by Linderman, Michael D, Brandt, Tracy, Edelmann, Lisa, Jabado, Omar, Kasai, Yumi, Kornreich, Ruth, Mahajan, Milind, Shah, Hardik, Kasarskis, Andrew, Schadt, Eric E

“…Whole exome and genome sequencing (WES/WGS) is now routinely offered as a clinical test by a growing number of laboratories. As part of the test design process…”
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