Search Results - "Milgram, N.W."

The oil-rich alga Schizochytrium sp as a dietary source of docosahexaenoic acid improves shape discrimination learning associated with visual processing in a canine model of senescence by Hadley, K.B, Bauer, J, Milgram, N.W

“…Abstract Whole cell Schizochytrium sp. is a rich source of omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) including docosahexaenoic acid (DHA), an…”
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P2-389: Metabolic treatments for Alzheimer's disease by Costantini, Lauren C, Studzinski, C.M, Araujo, J.A, MacKay, W.A, Webb, R.L, Beckett, T.L, Murphy, M.P, Sullivan, P.G, Burnham, W.M, Milgram, N.W, Vogel, J, Barr, L, Henderson, S.T

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Open Field Activity and Human Interaction as a Function of Age and Breed in Dogs by Head, E, Callahan, H, Cummings, B.J, Cotman, C.W, Ruehl, W.W, Muggenberg, B.A, Milgram, N.W

“…Open field (OF) activity was studied in kennel reared purebred beagles from two separate colonies (2–13 years in age) and pound source mixed breed dogs (9…”
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Long-term potentiation phenomena in the rat limbic forebrain by Racine, R J, Milgram, N W, Hafner, S

“…Long-term potentiation (LTP) phenomena were investigated in several limbic forebrain pathways. With the possible exception of the lateral olfactory tract, LTP…”
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Behavioral Activating Effects of Adrafinil in Aged Canines by Siwak, C.T, Gruet, P, Woehrlé, F, Schneider, M, Muggenburg, B.A, Murphey, H.L, Callahan, H, Milgram, N.W

“…Adrafinil, a vigilance enhancing pharmaceutical, was administered to aged dogs for 14 consecutive days at doses of 10, 20, 30, or 40 mg/kg using a crossover…”
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A Simple and Rapid Test of Sensorimotor Function in the Aged Rat by Murphy, M.P., Rick, J.T., Milgram, N.W., Ivy, G.O.

“…A total of 107 Fischer 344 rats (male and female, 2 to 29 months old) were tested on three tasks designed to measure sensorimotor function. In the first task,…”
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Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study by Milgram, N.W., Head, E., Zicker, S.C., Ikeda-Douglas, C.J., Murphey, H., Muggenburg, B., Siwak, C., Tapp, D., Cotman, C.W.

“…The effectiveness of two interventions, dietary fortification with antioxidants and a program of behavioral enrichment, was assessed in a longitudinal study of…”
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Acetyl-L-carnitine and α-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests by Milgram, N.W, Araujo, J.A, Hagen, T.M, Treadwell, B.V, Ames, B.N

“…Beagle dogs between 7.6 and 8.8 years of age administered a twice daily supplement of α-lipoic acid (LA) and acetyl-L-carnitine (ALC) over ~2 months made…”
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Short-term potentiation phenomena in the rat limbic forebrain by Racine, R J, Milgram, N W

“…Several types of short-term postactivation potentiation (PAP) effect were examined in limbic forebrain pathways in the chronic rat. We tested 9 different…”
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Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine by Araujo, J.A, Landsberg, G.M, Milgram, N.W, Miolo, A

“…Aged dogs demonstrate cognitive decline that is linked to brain aging. The purpose of the present study was to examine if a commercially available…”
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Synaptic structural plasticity following repetitive activation in the rat hippocampus by Petit, T L, LeBoutillier, J C, Markus, E J, Milgram, N W

“…The morphological effects of repetitive neuronal activation following systemic kainic acid administration were examined in hippocampal CA1 stratum radiatum…”
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Modeling anxiety in beagle dogs by de Rivera, C., Araujo, J.A., Milgram, N.W.

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Dietary enrichment counteracts age-associated cognitive dysfunction in canines by Milgram, N.W, Zicker, S.C, Head, E, Muggenburg, B.A, Murphey, H, Ikeda-Douglas, C.J, Cotman, C.W

“…Advanced age is accompanied by cognitive decline indicative of central nervous system dysfunction. One possibly critical causal factor is oxidative stress…”
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Region-specific age at onset of β-amyloid in dogs by Head, E, McCleary, R, Hahn, F.F, Milgram, N.W, Cotman, C.W

“…Cortical patterns of β-amyloid (Aβ) deposition were evaluated in 40 beagle dogs ranging in age from 2 to 18 years. Aβ deposition in the prefrontal, occipital,…”
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Assessment of cognitive dysfunction in companion dogs by Mongillo, P., Araujo, J.A., Landsberg, G.M., Milgram, N.W.

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Visual-discrimination learning ability and β-amyloid accumulation in the dog by Head, E., Callahan, H., Muggenburg, B.A., Cotman, C.W., Milgram, N.W.

“…Young, middle-aged, and old beagle dogs were tested on several visual-discrimination tasks: reward- and object-approach learning, object discrimination and…”
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Enhanced spatial ability in aged dogs following dietary and behavioural enrichment by Nippak, P.M.D., Mendelson, J., Muggenburg, B., Milgram, N.W.

“…We examined the benefits of a broad spectrum antioxidant diet and enrichment comprised of physical exercise, environmental stimulants and cognitive testing, on…”
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novel cognitive palatability assessment protocol for dogs by Araujo, J.A, Milgram, N.W

“…Assessment of canine palatability is important for both the pet food and pharmaceutical industries; however, the current palatability assessment protocols are…”
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Effects of acetyl-L-carnitine and Lipoic Acid supplementation on cognition in aged beagles by Christie, L.-A., Opii, W.O., Head, E., Araujo, J.A., De Rivera, C., Milgram, N.W., Cotman, C.W.

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Dose-specific effects of scopolamine on canine cognition: Impairment of visuospatial memory, but not visuospatial discrimination by ARAUJO, J. A, CHAN, A. D. F, WINKA, L. L, SEYMOUR, P. A, MILGRAM, N. W

“…The cholinergic system is linked extensively to memory, but its exact role remains controversial. In particular, scopolamine-induced impairment in rodents is…”
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