Search Results - "Milger, K."
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Assessing health-related quality of life in patients with interstitial lung diseases
Published in BMC pulmonary medicine (13-09-2024)“…The R-Scale-PF was proposed to evaluate the health-related quality of life (HRQoL) in patients with idiopathic pulmonary fibrosis (IPF). We generated a German…”
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Identification of a plasma miRNA biomarker signature for allergic asthma: A translational approach
Published in Allergy (Copenhagen) (01-12-2017)“…Background Asthma is a heterogeneous chronic disease with different phenotypes and treatment responses. Thus, there is a high clinical need for molecular…”
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Bronchodilator Reversibility in the GAN Severe Asthma Cohort
Published in Journal of investigational allergology & clinical immunology (01-01-2023)“…Positive bronchodilator reversibility (BDR) is a diagnostic criterion for asthma. However, patients with asthma may exhibit a negative BDR response. Aim: To…”
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Prevalence of Patients with Uncontrolled Asthma Despite NVL/GINA Step 4/5 Treatment in Germany
Published in Journal of asthma and allergy (01-01-2022)“…Purpose: Asthma is one of the most prevalent chronic diseases in Germany affecting 4-5% of all adults and 10% of children. Despite the availability of…”
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Switch from IL-5 to IL-5-Receptor α Antibody Treatment in Severe Eosinophilic Asthma
Published in Journal of asthma and allergy (01-01-2020)“…Anti-IL-5 antibodies represent an established therapy for severe eosinophilic asthma (SEA), but some patients show inadequate response. The objective of this…”
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Real-World Multicenter Experience with Mepolizumab and Benralizumab in the Treatment of Uncontrolled Severe Eosinophilic Asthma Over 12 Months
Published in Journal of asthma and allergy (01-01-2021)“…Purpose: Treatment of severe eosinophilic asthma (SEA) has been revolutionized by the development of monoclonal antibodies targeting underlying immunological…”
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Real-World Experience on the Use of Mepolizumab from the Severe Asthma Registry of the German Asthma Net (MepoGAN-Study)
Published in Journal of asthma and allergy (01-01-2023)“…The German Asthma Net (GAN) operates a Severe Asthma Registry that provides an overview of the clinical presentation and management of patients with severe…”
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Maintenance OCS Were Used More Frequently Than Biologics in Patients with Uncontrolled GINA 4/5 Asthma in Germany in 2019
Published in Journal of asthma and allergy (01-11-2024)“…Asthma is affecting 4-5% of all adults (10% of children) in Germany, ≥ half are inadequately controlled. In 2019 up to 54 thousand patients suffered from…”
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Benralizumab Reduces Respiratory Exacerbations and Oral Glucocorticosteroid Dose in Patients with Severe Asthma and Eosinophilic Granulomatosis with Polyangiitis
Published in Journal of asthma and allergy (30-06-2024)“…Benralizumab reduces exacerbations and long-term oral glucocorticosteroid (OCS) exposure in patients with severe eosinophilic asthma. In patients with…”
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Domestic Parasitic Infections in Patients with Asthma and Eosinophilia in Germany - Three Cases with Learnings in the Era of Anti- IL5 Treatments
Published in Journal of asthma and allergy (01-01-2023)“…Eosinophilic inflammation is a hallmark of asthma, and blood eosinophilia has been established as a biomarker for phenotyping asthma and predicting the…”
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Identification of a plasma mi RNA biomarker signature for allergic asthma: A translational approach
Published in Allergy (Copenhagen) (01-12-2017)“…Abstract Background Asthma is a heterogeneous chronic disease with different phenotypes and treatment responses. Thus, there is a high clinical need for…”
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Health Care Situation in the Treatment of Uncontrolled GINA Step 4/5 Patients in Germany
Published in Journal of asthma and allergy (01-01-2023)“…It has been estimated that, in 2019, 54,000 patients in Germany had uncontrolled GINA step 4/5 asthma. In the current study we analyzed which health care…”
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A101 LYMPHOID CELLS AND LUNG INFLAMMATION: The Role Of Ccr2+ Cd4 T Cells In Lung Fibrosis
Published in American journal of respiratory and critical care medicine (01-01-2014)Get full text
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Identification of a novel SERPINA-1 mutation causing alpha-1 antitrypsin deficiency in a patient with severe bronchiectasis and pulmonary embolism
Published in International journal of chronic obstructive pulmonary disease (07-05-2015)“…Deficiency in the serine protease inhibitor, alpha-1 antitrypsin (AAT), is known to cause emphysema and liver disease. Other manifestations, including airway…”
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Identification of a novel SERPINA-1mutation causing alpha-1 antitrypsin deficiency in a patient with severe bronchiectasis and pulmonary embolism
Published in International journal of chronic obstructive pulmonary disease (01-01-2015)“…Deficiency in the serine protease inhibitor, alpha-1 antitrypsin (AAT), is known to cause emphysema and liver disease. Other manifestations, including airway…”
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EARLY AND SUSTAINED ASTHMA CONTROL OVER 24 WEEKS AFTER TEZEPELUMAB INITIATION: REAL-WORLD ASCENT STUDY
Published in Annals of allergy, asthma, & immunology (01-11-2024)“…Randomized controlled trials have demonstrated the efficacy of tezepelumab in patients with severe, uncontrolled asthma (SUA). This interim analysis of the…”
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Personalisierte Medizin bei pulmonaler Hypertonie
Published in Pneumologe (01-03-2019)“…Zusammenfassung Die pulmonale Hypertonie ist eine heterogene Gruppe von Erkrankungen, welche über den erhöhten mittleren pulmonal-arteriellen Druck definiert…”
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The role of coronary artery disease in lung transplantation
Published in European heart journal (09-11-2023)“…Abstract Background Coronary artery disease (CAD) is a common comorbidity in patients suffering from terminal lung disease and a recurrent problem in…”
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