Search Results - "Miles, Tiffany K."
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410 Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge and Resistance in Male Offspring to a High Fat Diet
Published in Journal of clinical and translational science (01-04-2022)“…OBJECTIVES/GOALS: Maternal undernutrition, a form of malnutrition, can alter neonatal leptin signaling and result in metabolic dysfunction in adulthood. We…”
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The STAT5A-Mediated Induction of Pyruvate Dehydrogenase Kinase 4 Expression by Prolactin or Growth Hormone in Adipocytes
Published in Diabetes (New York, N.Y.) (01-06-2007)“…The STAT5A-Mediated Induction of Pyruvate Dehydrogenase Kinase 4 Expression by Prolactin or Growth Hormone in Adipocytes Ursula A. White , Ann A. Coulter ,…”
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Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism
Published in Endocrinology (Philadelphia) (23-12-2023)“…Abstract Anterior pituitary cell function requires a high level of protein synthesis and secretion which depend heavily on mitochondrial adenosine triphosphate…”
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Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
Published in Endocrinology (Philadelphia) (01-09-2023)“…Abstract The anterior pituitary controls key biological processes, including growth, metabolism, reproduction, and stress responses through distinct cell types…”
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Metabolic signalling to somatotrophs: Transcriptional and post‐transcriptional mediators
Published in Journal of neuroendocrinology (01-11-2020)“…In normal individuals, pituitary somatotrophs optimise body composition by responding to metabolic signals from leptin. To identify mechanisms behind the…”
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Sex differences in somatotrope response to fasting: biphasic responses in male mice
Published in Journal of endocrinology (01-12-2020)“…Anterior pituitary somatotropes are important metabolic sensors responding to leptin by secreting growth hormone (GH). However, reduced leptin signals caused…”
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Maternal undernutrition results in transcript changes in male offspring that may promote resistance to high fat diet induced weight gain
Published in Frontiers in endocrinology (Lausanne) (17-01-2024)“…Maternal nutrition during embryonic development and lactation influences multiple aspects of offspring health. Using mice, this study investigates the effects…”
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Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum
Published in Cell death discovery (18-02-2020)“…Genetic obesity increases in liver phosphatidylcholine (PC)/phosphatidylethanolamine (PE) ratio, inducing endoplasmic reticulum (ER) stress without concomitant…”
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Somatotrope Responses to Acute and Prolonged Loss of Leptin Signaling
Published in The FASEB journal (01-04-2020)“…Abstract only In mice and humans, fasting results in a rise of serum growth hormone (GH). In mice, this coincides with increased Gh and growth hormone…”
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8649 Ablation of Leptin Receptors in Somatotropes Impacts Transcriptomic Plasticity in the Pou1f1 Lineage of Female Pituitary Cells
Published in Journal of the Endocrine Society (05-10-2024)“…Abstract Disclosure: T.K. Miles: None. A.K. Odle: None. S. Byrum: None. A. Lagasse: None. A. Haney: None. V.G. Ortega: None. A. Herdman: None. M.C. MacNicol:…”
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THU043 Single-cell Transcriptomics Show Sex-specific Responses To A High Fat Diet, Under Thermoneutral Conditions, Pointing To Reduced Pituitary Plasticity
Published in Journal of the Endocrine Society (05-10-2023)“…Abstract Disclosure: T.K. Miles: None. A.N. Lagasse: None. A.K. Odle: None. S.S. Lira: None. M.M. Syed: None. N. Akhter: None. M.C. MacNicol: None. A.M…”
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8572 A 30% Maternal Caloric Restriction Alters Expression of Musashi Targets in the Neonatal and Adult Pituitary Proteomes of FVB Mice
Published in Journal of the Endocrine Society (05-10-2024)“…Abstract Disclosure: T.K. Miles: None. V.G. Ortega: None. K.D. Carroll: None. A.K. Odle: None. S.D. Byrum: None. A.J. Gies: None. A.N. Lagasse: None. A.C…”
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Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge that Promotes Resistance in Male Offspring to a High Fat Diet
Published in Journal of the Endocrine Society (03-05-2021)“…Abstract Malnutrition alters leptin signaling, resulting in dysregulation of pituitary somatotropes that may be sex-specific. We reported sex differences in…”
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SAT-287 Mild Perinatal Undernutrition Results in Underweight Pups and a Premature Neonatal Leptin Surge
Published in Journal of the Endocrine Society (08-05-2020)“…Abstract Malnutrition causes dysregulated pituitary function, which may in part be due to lowered leptin signals. We showed that loss of somatotrope leptin…”
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15
Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum
Published in Cell death discovery (18-02-2020)“…Genetic obesity increases in liver phosphatidylcholine (PC)/phosphatidylethanolamine (PE) ratio, inducing endoplasmic reticulum (ER) stress without concomitant…”
Get full text
Journal Article