Search Results - "Miles, K"
-
1
Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy
Published in Nature communications (09-02-2021)“…Polycomb repressive complex 1 (PRC1) is an essential chromatin-based repressor of gene transcription. How PRC1 engages with chromatin to identify its target…”
Get full text
Journal Article -
2
PRC1 Catalytic Activity Is Central to Polycomb System Function
Published in Molecular cell (20-02-2020)“…The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite being extensively studied, how the Polycomb system selects…”
Get full text
Journal Article -
3
Region Capture Micro-C reveals coalescence of enhancers and promoters into nested microcompartments
Published in Nature genetics (01-06-2023)“…Although enhancers are central regulators of mammalian gene expression, the mechanisms underlying enhancer–promoter (E-P) interactions remain unclear…”
Get full text
Journal Article -
4
"Stay at Home, Protect the National Health Service, Save Lives": A cost benefit analysis of the lockdown in the United Kingdom
Published in International journal of clinical practice (Esher) (01-03-2021)“…The COVID-19 pandemic has transformed lives across the world. In the UK, a public health driven policy of population "lockdown" has had enormous personal and…”
Get more information
Journal Article -
5
Temperature effects on food supply and chick mortality in tree swallows (Tachycineta bicolor)
Published in Oecologia (01-09-2013)“…Tree swallow (Tachycineta bicolor) breeding success in Ithaca, NY, USA, over the past quarter century has shown generally healthy fledgling production…”
Get full text
Journal Article -
6
A Behavioral Syndrome Linking Boldness and Flexibility Facilitates Invasion Success in Sticklebacks
Published in The American naturalist (01-12-2022)“…AbstractFor a species to expand its range, it needs to be good at dispersing and also capable of exploiting resources and adapting to different environments…”
Get more information
Journal Article -
7
Tumour heterogeneity in oesophageal cancer assessed by CT texture analysis: Preliminary evidence of an association with tumour metabolism, stage, and survival
Published in Clinical radiology (01-02-2012)“…Aim To undertake a pilot study assessing whether tumour heterogeneity evaluated using computed tomography texture analysis (CTTA) has the potential to provide…”
Get full text
Journal Article -
8
Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells
Published in Cell reports (Cambridge) (21-01-2020)“…How chromosome organization is related to genome function remains poorly understood. Cohesin, loop extrusion, and CCCTC-binding factor (CTCF) have been…”
Get full text
Journal Article -
9
Apoptotic cells protect mice from autoimmune inflammation by the induction of regulatory B cells
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2007)“…The maintenance of immune tolerance to apoptotic cells (AC) within an inflammatory milieu is vital to prevent autoimmunity. To investigate this, we…”
Get full text
Journal Article -
10
Neurogenomic insights into paternal care and its relation to territorial aggression
Published in Nature communications (30-09-2019)“…Motherhood is characterized by dramatic changes in brain and behavior, but less is known about fatherhood. Here we report that male sticklebacks—a small fish…”
Get full text
Journal Article -
11
Perfusion CT for the assessment of tumour vascularity: which protocol?
Published in British journal of radiology (01-01-2003)“…Perfusion CT is a technique that can be readily incorporated into the existing CT protocols that continue to provide the mainstay for anatomical imaging in…”
Get full text
Journal Article -
12
Automatic Age Estimation Based on Facial Aging Patterns
Published in IEEE transactions on pattern analysis and machine intelligence (01-12-2007)“…While recognition of most facial variations, such as identity, expression, and gender, has been extensively studied, automatic age estimation has rarely been…”
Get full text
Journal Article -
13
Current status and guidelines for the assessment of tumour vascular support with dynamic contrast-enhanced computed tomography
Published in European radiology (01-07-2012)“…Dynamic contrast-enhanced computed tomography (DCE-CT) assesses the vascular support of tumours through analysis of temporal changes in attenuation in blood…”
Get full text
Journal Article -
14
A Review of Cognitive Abilities in Dogs, 1911 Through 2016: More Individual Differences, Please
Published in Current directions in psychological science : a journal of the American Psychological Society (01-10-2016)“…In this review, we pose and respond to three questions concerning canine cognition: How has the history of this field influenced what we currently know about…”
Get full text
Journal Article -
15
Partner gaze shapes the relationship between symptoms of psychopathology and interpersonal coordination
Published in Scientific reports (21-06-2024)“…Interpersonal coordination is a key determinant of successful social interaction but can be disrupted when people experience symptoms related to social anxiety…”
Get full text
Journal Article -
16
Testing the predictions of coping styles theory in threespined sticklebacks
Published in Behavioural processes (01-03-2017)“…•Individual animals have different ways of coping with changes in the environment.•Individual sticklebacks differ in boldness, stress response and…”
Get full text
Journal Article -
17
Prophylactic and therapeutic intranasal administration with an immunomodulator, Hiltonol® (Poly IC:LC), in a lethal SARS-CoV-infected BALB/c mouse model
Published in Antiviral research (01-03-2017)“…Hiltonol®, (Poly IC:LC), a potent immunomodulator, is a synthetic, double-stranded polyriboinosinic-polyribocytidylic acid (poly IC) stabilized with…”
Get full text
Journal Article -
18
The rhythm of rapport: Interpersonal synchrony and social perception
Published in Journal of experimental social psychology (01-05-2009)“…The temporal coordination of behavior during dyadic interactions is a foundation for effective social exchange with synchronized actions enhancing perceptions…”
Get full text
Journal Article -
19
Predictors of individual variation in reversal learning performance in three-spined sticklebacks
Published in Animal cognition (01-09-2020)“…Behavioral flexibility is a type of phenotypic plasticity that can influence how animals cope with environmental change and is often measured with a reversal…”
Get full text
Journal Article -
20
BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome
Published in Genes & development (01-05-2021)“…Histone-modifying systems play fundamental roles in gene regulation and the development of multicellular organisms. Histone modifications that are enriched at…”
Get full text
Journal Article