Search Results - "Miles, John M"
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METFORMIN: NONGLYCEMIC EFFECTS AND POTENTIAL NOVEL INDICATIONS
Published in Endocrine practice (01-08-2016)“…Metformin is the most commonly prescribed drug for the treatment of type 2 diabetes because of its apparent robust effects in reducing cardiovascular risk…”
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Essential Fatty Acid Requirements and Intravenous Lipid Emulsions
Published in JPEN. Journal of parenteral and enteral nutrition (01-08-2019)“…Linoleic acid (LA) and α‐linolenic acid (ALA) must be supplied to the human body and are therefore considered essential fatty acids. This narrative review…”
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Energy expenditure in hospitalized patients: implications for nutritional support
Published in Mayo Clinic proceedings (01-06-2006)“…An understanding of energy expenditure in hospitalized patients is necessary to determine optimal energy supply in the care of individuals who require…”
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Can Serum β-Hydroxybutyrate Be Used to Diagnose Diabetic Ketoacidosis?
Published in Diabetes care (01-04-2008)“…OBJECTIVE:--Current criteria for the diagnosis of diabetic ketoacidosis (DKA) are limited by their nonspecificity (serum bicarbonate [HCO₃] and pH) and…”
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Reduced Liver-Specific PGC1a Increases Susceptibility for Short-Term Diet-Induced Weight Gain in Male Mice
Published in Nutrients (28-07-2021)“…The central integration of peripheral neural signals is one mechanism by which systemic energy homeostasis is regulated. Previously, increased acute food…”
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The effects of cognitive behavioral therapy for insomnia in people with type 2 diabetes mellitus, pilot RCT part II: diabetes health outcomes
Published in BMC endocrine disorders (05-09-2020)“…Abstract Background Previous studies have shown the negative impact of sleep disturbances, specifically insomnia symptoms, on glucose metabolism for people…”
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Combined effect of cardiorespiratory fitness and adiposity on mortality in patients with coronary artery disease
Published in The American heart journal (01-03-2011)“…Background High cardiorespiratory fitness and body mass index (BMI) are associated with decreased mortality in patients with coronary artery disease. Our…”
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Hepatic dysfunction in patients receiving intravenous lipid emulsions
Published in Current opinion in clinical nutrition and metabolic care (01-05-2023)“…Until recently, intravenous lipid emulsions (ILEs) have consisted of soybean oil (SO) only. This review addresses recent developments in the field, including…”
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The neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis
Published in Molecular metabolism (Germany) (01-01-2017)“…Abstract Objectives Obesity is characterized by excessive fat mass and is associated with serious diseases such as type 2 diabetes. Targeting excess fat mass…”
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Sympathetic support of energy expenditure and sympathetic nervous system activity after gastric bypass surgery
Published in Obesity (Silver Spring, Md.) (01-03-2013)“…Objective: This study was designed to determine how gastric bypass affects the sympathetically‐mediated component of resting energy expenditure (REE) and…”
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Effect of Orlistat in Overweight and Obese Patients With Type 2 Diabetes Treated With Metformin
Published in Diabetes care (01-07-2002)“…Effect of Orlistat in Overweight and Obese Patients With Type 2 Diabetes Treated With Metformin John M. Miles , MD , Lawrence Leiter , MD , Priscilla Hollander…”
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Short-Term Estradiol Supplementation Potentiates Low-Dose Ghrelin Action in the Presence of GHRH or Somatostatin in Older Women
Published in The journal of clinical endocrinology and metabolism (01-01-2014)“…Context: Ghrelin is a potent gastric-derived GH-releasing peptide. How ghrelin interacts with sex steroids, GHRH, and somatostatin (SS) is not known…”
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Tripartite Control of Dynamic ACTH-Cortisol Dose Responsiveness by Age, Body Mass Index, and Gender in 111 Healthy Adults
Published in The journal of clinical endocrinology and metabolism (01-09-2011)“…Background: Recent analyses in small cohorts suggest that pituitary hormones exert time-varying (viz., initial and delayed) dynamic dose-responsive effects on…”
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Hyperglycemic crises in adult patients with diabetes
Published in Diabetes care (01-07-2009)“…[...] the long-term impact of uncontrolled diabetes and its economic burden could be more significant because it can contribute to various complications…”
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Splanchnic Spillover of Extracellular Lipase–Generated Fatty Acids in Overweight and Obese Humans
Published in Diabetes (New York, N.Y.) (01-12-2007)“…Splanchnic Spillover of Extracellular Lipase–Generated Fatty Acids in Overweight and Obese Humans Robert H. Nelson 1 , Rita Basu 1 , C. Michael Johnson 2 ,…”
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What Does the Measurement of Whole-Body Fatty Acid Rate of Appearance in Plasma by Using a Fatty Acid Tracer Really Mean?
Published in Diabetes (New York, N.Y.) (01-07-2003)“…What Does the Measurement of Whole-Body Fatty Acid Rate of Appearance in Plasma by Using a Fatty Acid Tracer Really Mean? Bettina Mittendorfer 1 , Olivia Liem…”
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Myocardial Uptake of Circulating Triglycerides in Nondiabetic Patients With Heart Disease
Published in Diabetes (New York, N.Y.) (01-02-2007)“…Myocardial Uptake of Circulating Triglycerides in Nondiabetic Patients With Heart Disease Robert H. Nelson 1 , Abhiram Prasad 2 , Amir Lerman 2 and John M…”
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Enhanced lipogenesis through Pparγ helps cavefish adapt to food scarcity
Published in Current biology (23-05-2022)“…Nutrient availability varies seasonally and spatially in the wild. While many animals, such as hibernating animals or migrating birds, evolved strategies to…”
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Relation of adipose tissue to metabolic flexibility
Published in Diabetes research and clinical practice (01-01-2009)“…Abstract Metabolic flexibility is the capacity for skeletal muscle to shift reliance between lipids and glucose during fasting or in response to insulin. We…”
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Estrogen Supplementation Selectively Enhances Hypothalamo-Pituitary Sensitivity to Ghrelin in Postmenopausal Women
Published in The journal of clinical endocrinology and metabolism (01-10-2008)“…Context: Sex-steroid hormones amplify pulsatile GH secretion by unknown mechanisms. Ghrelin is the most potent natural GH secretagogue discovered to date. A…”
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