Search Results - "Milek, Jacek"

The Fragile X mental retardation protein regulates matrix metalloproteinase 9 mRNA at synapses by Janusz, Aleksandra, Milek, Jacek, Perycz, Malgorzata, Pacini, Laura, Bagni, Claudia, Kaczmarek, Leszek, Dziembowska, Magdalena

“…Activity-dependent protein synthesis at synapses is dysregulated in the Fragile X syndrome (FXS). This process contributes to dendritic spine dysmorphogenesis…”
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Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner by Janusz-Kaminska, Aleksandra, Brzozowska, Agnieszka, Tempes, Aleksandra, Urbanska, Malgorzata, Blazejczyk, Magdalena, Miłek, Jacek, Kuzniewska, Bozena, Zeng, Juan, Wesławski, Jan, Kisielewska, Katarzyna, Bassell, Gary J, Jaworski, Jacek

“…Synaptic plasticity is a process that shapes neuronal connections during neurodevelopment and learning and memory. Autophagy is a mechanism that allows the…”
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Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage by Chmielewska, Joanna J., Kuzniewska, Bozena, Milek, Jacek, Urbanska, Katarzyna, Dziembowska, Magdalena

“…Neuroligins (NLGNs) are cell adhesion molecules located on the postsynaptic side of the synapse that interact with their presynaptic partners neurexins to…”
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Activity-dependent local translation of matrix metalloproteinase-9 by Dziembowska, Magdalena, Milek, Jacek, Janusz, Aleksandra, Rejmak, Emilia, Romanowska, Ewelina, Gorkiewicz, Tomasz, Tiron, Adrian, Bramham, Clive R, Kaczmarek, Leszek

“…Local, synaptic synthesis of new proteins in response to neuronal stimulation plays a key role in the regulation of synaptic morphogenesis. Recent studies…”
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Mutation in the mitochondrial chaperone TRAP1 leads to autism with more severe symptoms in males by Rydzanicz, Małgorzata, Kuzniewska, Bozena, Magnowska, Marta, Wójtowicz, Tomasz, Stawikowska, Aleksandra, Hojka, Anna, Borsuk, Ewa, Meyza, Ksenia, Gewartowska, Olga, Gruchota, Jakub, Miłek, Jacek, Wardaszka, Patrycja, Chojnicka, Izabela, Kondrakiewicz, Ludwika, Dymkowska, Dorota, Puścian, Alicja, Knapska, Ewelina, Dziembowski, Andrzej, Płoski, Rafał, Dziembowska, Magdalena

“…There is increasing evidence of mitochondrial dysfunction in autism spectrum disorders (ASD), but the causal relationships are unclear. In an ASD patient whose…”
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miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA by Jasińska, Magdalena, Miłek, Jacek, Cymerman, Iwona A., Łęski, Szymon, Kaczmarek, Leszek, Dziembowska, Magdalena

“…Mir-132 is a neuronal activity-regulated microRNA that controls the morphology of dendritic spines and neuronal transmission. Similar activities have recently…”
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Impaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome by Chojnacka, Magdalena, Beroun, Anna, Magnowska, Marta, Stawikowska, Aleksandra, Cysewski, Dominik, Milek, Jacek, Dziembowska, Magdalena, Kuzniewska, Bozena

“…Fragile X syndrome (FXS) is the most common monogenetic cause of inherited intellectual disability and autism in humans. One of the well-characterized…”
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Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β by Cymerman, Iwona A, Gozdz, Agata, Urbanska, Malgorzata, Milek, Jacek, Dziembowska, Magdalena, Jaworski, Jacek

“…Although memories appear to be elusive phenomena, they are stored in the network of physical connections between neurons. Dendritic spines, which are…”
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Disrupting interaction between miR-132 and Mmp9 3′UTR improves synaptic plasticity and memory in mice by Kuzniewska, Bozena, Rejmak, Karolina, Nowacka, Agata, Ziółkowska, Magdalena, Milek, Jacek, Magnowska, Marta, Gruchota, Jakub, Gewartowska, Olga, Borsuk, Ewa, Salamian, Ahmad, Dziembowski, Andrzej, Radwanska, Kasia, Dziembowska, Magdalena

“…As microRNAs have emerged to be important regulators of molecular events occurring at the synapses, the new questions about their regulatory effect on the…”
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TIAR and FMRP shape pro-survival nascent proteome of leukemia cells in the bone marrow microenvironment by Wolczyk, Magdalena, Serwa, Remigiusz, Kominek, Agata, Klejman, Agata, Milek, Jacek, Chwałek, Marta, Turos-Korgul, Laura, Charzyńska, Agata, Dabrowski, Michal, Dziembowska, Magdalena, Skorski, Tomasz, Piwocka, Katarzyna, Podszywalow-Bartnicka, Paulina

“…Chronic myeloid leukemia (CML) cells circulate between blood and bone marrow niche, representing different microenvironments. We studied the role of the two…”
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Mitochondrial protein biogenesis in the synapse is supported by local translation by Kuzniewska, Bozena, Cysewski, Dominik, Wasilewski, Michal, Sakowska, Paulina, Milek, Jacek, Kulinski, Tomasz M, Winiarski, Maciej, Kozielewicz, Pawel, Knapska, Ewelina, Dadlez, Michal, Chacinska, Agnieszka, Dziembowski, Andrzej, Dziembowska, Magdalena

“…Synapses are the regions of the neuron that enable the transmission and propagation of action potentials on the cost of high energy consumption and elevated…”
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Preparation of polysomal fractions from mouse brain synaptoneurosomes and analysis of polysomal-bound mRNAs by Kuzniewska, Bozena, Chojnacka, Magdalena, Milek, Jacek, Dziembowska, Magdalena

“…•A step-by-step reliable protocol to prepare synaptoneurosomes from rodent brain.•Polyribosome fractionation from synaptoneurosomes.•Extraction of proteins and…”
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Abstract 2642: Nascent proteome of leukemia cells in the hypoxic bone marrow microenvironment – role of TIAR and FMRP by Podszywalow-Bartnicka, Paulina, Wolczyk, Magdalena, Serwa, Remigiusz, Turos-Korgul, Laura, Milek, Jacek, Chwalek, Marta, Dabrowski, Michal, Dziembowska, Magdalena, Piwocka, Katarzyna

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Disrupting interaction between miR-132 and Mmp9 3'UTR improves synaptic plasticity and memory in mice by Kuzniewska, Bozena, Rejmak, Karolina, Nowacka, Agata, Ziółkowska, Magdalena, Milek, Jacek, Magnowska, Marta, Gruchota, Jakub, Gewartowska, Olga, Borsuk, Ewa, Salamian, Ahmad, Dziembowski, Andrzej, Radwanska, Kasia, Dziembowska, Magdalena

“…As microRNAs have emerged to be important regulators of molecular events occurring at the synapses, the new questions about their regulatory effect on the…”
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Structural Plasticity of Dendritic Spines Requires GSK3[alpha] and GSK3[beta] by Cymerman, Iwona A, Gozdz, Agata, Urbanska, Malgorzata, Milek, Jacek, Dziembowska, Magdalena, Jaworski, Jacek

“…Although memories appear to be elusive phenomena, they are stored in the network of physical connections between neurons. Dendritic spines, which are…”
Get full text