Search Results - "Mildner, Ana M."

The atomic-resolution structure of human caspase-8, a key activator of apoptosis by Watt, William, Koeplinger, Kenneth A, Mildner, Ana M, Heinrikson, Robert L, Tomasselli, Alfredo G, Watenpaugh, Keith D

“…Background: Caspases are a family of cysteine proteases that have important intracellular roles in inflammation and apoptosis. Caspase-8 activates downstream…”
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Processing of the Human Heparanase Precursor and Evidence That the Active Enzyme Is a Heterodimer by Fairbanks, Michael B., Mildner, Ana M., Leone, Joseph W., Cavey, Gregory S., Mathews, W. Rodney, Drong, Roger F., Slightom, Jerry L., Bienkowski, Michael J., Smith, Clark W., Bannow, Carol A., Heinrikson, Robert L.

“…Human platelet heparanase has been purified to homogeneity and shown to consist of two, non-covalently associated polypeptide chains of molecular masses 50 and…”
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Cation binding to the integrin CD11b I domain and activation model assessment by Baldwin, Eric T, Sarver, Ronald W, Bryant, Garold L, Curry, Kimberly A, Fairbanks, Michael B, Finzel, Barry C, Garlick, Robert L, Heinrikson, Robert L, Horton, Nancy C, Kelley, Laura-Lee C, Mildner, Ana M, Moon, Joseph B, Mott, John E, Mutchler, Veronica T, Tomich, Che-Shen C, Watenpaugh, Keith D, Wiley, Veronica H

“…Background: The integrin family of cell-surface receptors mediate cell adhesion through interactions with the extracellular matrix or other cell-surface…”
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The HIV-1 Protease as Enzyme and Substrate: Mutagenesis of Autolysis Sites and Generation of a Stable Mutant with Retained Kinetic Properties by Mildner, Ana M, Rothrock, Donna J, Leone, Joseph W, Bannow, Carol A, Lull, June M, Reardon, Ilene M, Sarcich, Jean L, Howe, W. Jeffrey, Tomich, Che-Shen C

“…Site-directed mutagenesis of autolysis sites in the human immunodeficiency virus type 1 (HIV-1) protease was applied in an analysis of enzyme specificity; the…”
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Caspase 8: An Efficient Method for Large-Scale Autoactivation of Recombinant Procaspase 8 by Matrix Adsorption and Characterization of the Active Enzyme by Koeplinger, Kenneth A., Mildner, Ana M., Leone, Joseph W., Wheeler, Jean S., Heinrikson, Robert L., Tomasselli, Alfredo G.

“…A gene coding for a truncated form of human procaspase 8 has been cloned and expressed in Escherichia coli. This construct contains M206 through D479 of human…”
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Porcine fatty acid synthase: cloning of a complementary DNA, tissue distribution of its mRNA and suppression of expression by somatotropin and dietary protein by Mildner, A M, Clarke, S D

“…A cDNA for porcine fatty acid synthase was isolated and used to examine the tissue distribution of fatty acid synthase mRNA within the pig and to determine the…”
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[W206R]-Procaspase 3: An Inactivatable Substrate for Caspase 8 by Rank, Kenneth B., Mildner, Ana M., Leone, Joseph W., Koeplinger, Kenneth A., Chou, K.C., Tomasselli, Alfredo G., Heinrikson, Robert L., Sharma, Satish K.

“…We report here the cloning and high-level expression of a soluble proform of human caspase 3 (Ser24-H277) engineered to contain a short stretch of N-terminal…”
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Production of Chemokines CTAPIII and NAP/2 by Digestion of Recombinant Ubiquitin–CTAPIII with Yeast Ubiquitin C-Terminal Hydrolase and Human Immunodeficiency Virus Protease by Mildner, Ana M., Paddock, Donna J., LeCureux, Lloyd W., Leone, Joseph W., Anderson, Donald C., Tomasselli, Alfredo G., Heinrikson, Robert L.

“…Recombinant yeast ubiquitin C-terminal hydrolase (YUH1), which has an N-terminal (His)6 tag, and an autolysis-resistant mutant of the human immunodeficiency…”
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Mutants of HIV-1 protease with enhanced stability to autodegradation by Tomasselli, A G, Mildner, A M, Rothrock, D J, Sarcich, J L, Lull, J, Leone, J, Heinrikson, R L

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Site-directed mutagenesis of HIV-1 protease: generation of mutant proteases with increased stability to autodigestion by Tomasselli, A G, Mildner, A M, Rothrock, D J, Sarcich, J L, Lull, J, Leone, J, Heinrikson, R

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