Search Results - "Milardi, D"

The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges by Tundo, G.R., Sbardella, D., Santoro, A.M., Coletta, A., Oddone, F., Grasso, G., Milardi, D., Lacal, P.M., Marini, S., Purrello, R., Graziani, G., Coletta, M.

“…Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that sustains proteostasis network under a large variety of physiopathological…”
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The insulin degrading enzyme activates ubiquitin and promotes the formation of K48 and K63 diubiquitin by Grasso, G, Lanza, V, Malgieri, G, Fattorusso, R, Pietropaolo, A, Rizzarelli, E, Milardi, D

“…We report an ATP-dependent ubiquitin conjugation with IDE which, in turn, promotes Ub-Ub linkages in tube tests. We propose a novel function for IDE as a…”
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Ubiquitin binds the amyloid β peptide and interferes with its clearance pathways by Bellia, F, Lanza, V, García-Viñuales, S, Ahmed, I. M. M, Pietropaolo, A, Iacobucci, C, Malgieri, G, D'Abrosca, G, Fattorusso, R, Nicoletti, V. G, Sbardella, D, Tundo, G. R, Coletta, M, Pirone, L, Pedone, E, Calcagno, D, Grasso, G, Milardi, D

“…Several lines of evidence point to a compromised proteostasis associated with a reduction of the Ubiquitin Proteasome System (UPS) activity in patients…”
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Combined evaluation of prolactin-induced peptide (PIP) and extracellular signal-regulated kinase (ERK) as new sperm biomarkers of FSH treatment efficacy in normogonadotropic idiopathic infertile men by Mancini, F., Di Nicuolo, F., Teveroni, E., Vergani, E., Bianchetti, G., Bruno, C., Grande, G., Iavarone, F., Maulucci, G., De Spirito, M., Urbani, A., Pontecorvi, A., Milardi, D.

“…Purpose Nearly, 40% of the causes of male infertility remain idiopathic. The only suggested treatment in idiopathic oligo- and/or asthenozoospermia in…”
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Experimental strain analysis on the entire bony leg compared with FE analysis by Filardi, V, Milardi, D

“…Abstract The present study addresses the question of evaluating, by combining both experimental and numerical approaches, the stress/strain distribution within…”
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Prevalence of morphometric vertebral fractures in “difficult” patients with acromegaly with different biochemical outcomes after multimodal treatment by Chiloiro, S., Mormando, M., Bianchi, A., Giampietro, A., Milardi, D., Bima, C., Grande, G., Formenti, A. M., Mazziotti, G., Pontecorvi, A., Giustina, A., De Marinis, L.

“…Introduction Skeletal fragility with high risk of vertebral fractures is an emerging complication of acromegaly in close relationship with duration of active…”
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Proteomic characterization of the qualitative and quantitative differences in cervical mucus composition during the menstrual cycle by Grande, G, Milardi, D, Vincenzoni, F, Pompa, G, Biscione, A, Astorri, A L, Fruscella, E, De Luca, A, Messana, I, Castagnola, M, Marana, R

“…The chemical composition of the cervical mucus (CM), its physical characteristics and the volume of secretion change cyclically throughout the menstrual cycle…”
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Endogenous and artificial miRNAs explore a rich variety of conformations: a potential relationship between secondary structure and biological functionality by Gangemi, C. M. A., Alaimo, S., Pulvirenti, A., García-Viñuales, Sara, Milardi, D., Falanga, A. P., Fragalà, M. E., Oliviero, G., Piccialli, G., Borbone, N., Ferro, A., D’Urso, A., Croce, C. M., Purrello, R.

“…Mature microRNAs are short non-coding RNA sequences which upon incorporation into the RISC ribonucleoprotein complex, play a crucial role in regulation of gene…”
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Growth hormone receptor isoforms and fracture risk in adult-onset growth hormone-deficient patients by Mormando, M., Chiloiro, S., Bianchi, A., Giampietro, A., Angelini, F., Tartaglione, L., Nasto, L., Milardi, D., Formenti, A.M., Giustina, A., De Marinis, L.

“…Summary Introduction Growth hormone deficiency is considered the most important factor determining skeletal fragility in hypopituitary patients. Osteoblasts…”
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Transforming Growth Factor Beta 1 and Vascular Endothelial Growth Factor Levels in the Pathogenesis of Periodontal Disease by Matarese, G., Isola, G., Anastasi, G.P., Cutroneo, G., Cordasco, G., Favaloro, A., Vita, G., Vermiglio, G., Milardi, D., Zizzari, V.L., Tetè, S., Perillo, L.

“…Periodontal disease is characterized by inflammation and bone loss. The balance between inflammatory mediators and their counter-regulatory molecules may be…”
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Statistical investigation about spinal clinical asymmetry in a school population by Tisano, A., Alito, A., Milardi, D., Fazio, R., Virelli, L., Zanella, C., Ruggeri, C., Filardi, V., Bruschetta, D.

“…Spinal disorders and obesity are increasing and are an important cause for concern among healthcare and educational bodies. There is a wide variability in the…”
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4(α-L-RHAMNOSYLOXY)-BENZYL ISOTHIOCYANATE, A BIOACTIVE PHYTOCHEMICAL THAT DEFENDS CEREBRAL TISSUE AND PREVENTS SEVERE DAMAGE INDUCED BY FOCAL ISCHEMIA/REPERFUSION by Galuppo, M, Giacoppo, S, Iori, R, De Nicola, G R, Milardi, D, Bramanti, P, Mazzon, E

“…Natural compounds are a promising source to treat several pathologies. The present study shows the in vivo pharmacological beneficial effect of…”
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Inter-hemispheric Claustral Connections in Human Brain: A Constrained Spherical Deconvolution-Based Study by Arrigo, A., Mormina, E., Calamuneri, A., Gaeta, M., Granata, F., Marino, S., Anastasi, G. P., Milardi, D., Quartarone, A.

“…Purpose Complex claustral connection network was widely demonstrated both in humans and animals. Moreover, several studies have suggested that claustral…”
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Prednisone treatment in infertile patients with oligozoospermia and accessory gland inflammatory alterations by Milardi, D., Luca, G., Grande, G., Ghezzi, M., Caretta, N., Brusco, G., De Filpo, G., Marana, R., Pontecorvi, A., Calafiore, R., Foresta, C., Garolla, A.

“…Summary The association between inflammation of the male reproductive system and oligozoospermia has been frequently reported in the clinical work‐up of male…”
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Protein expression of PTTG-1, OCT-4, and KLF-4 in testis seminoma by Gulino, G., Milardi, D., Grande, G., Martini, M., Cenci, T., Mancini, F., Bianchi, A., Pontecorvi, A., Pierconti, F., Bassi, P.F.

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Pituitary-tumour-transforming-gene 1 expression in testicular cancer by Pierconti, F., Milardi, D., Martini, M., Grande, G., Cenci, T., Gulino, G., Larocca, L. M., Rindi, G., Pontecorvi, A., De Marinis, L.

“…Summary Genomic instability is a feature of germ cell tumours. The pituitary‐tumour‐transforming‐gene 1 (PTTG1) is the major effector of chromosome segregation…”
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Double pituitary adenomas by Iacovazzo, D., Bianchi, A., Lugli, F., Milardi, D., Giampietro, A., Lucci-Cordisco, E., Doglietto, F., Lauriola, L., De Marinis, L.

“…Double pituitary adenomas represent up to 2.6 % of pituitary adenomas in large surgical series and up to 3.3 % of patients with Cushing’s disease have been…”
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Soluble urokinase‐type plasminogen activator receptor as a putative marker of male accessory gland inflammation by Autilio, C., Morelli, R., Milardi, D., Grande, G., Marana, R., Pontecorvi, A., Zuppi, C., Baroni, S.

“…Summary The association between male accessory gland infection/inflammation (MAGI) and infertility is well‐known in clinical practice. Standard semen analysis,…”
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Male Fertility and Reduction in Semen Parameters: A Single Tertiary-Care Center Experience by Milardi, D., Grande, G., Sacchini, D., Astorri, A. L., Pompa, G., Giampietro, A., De Marinis, L., Pontecorvi, A., Spagnolo, A. G., Marana, R.

“…Background. Infertility is both a clinical and a public problem, affecting the life of the couple, the healthcare services, and social environment. Standard…”
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Sarcoglycan complex in masseter and sternocleidomastoid muscles of baboons: an immunohistochemical study by Cutroneo, G, Centofanti, A, Speciale, F, Rizzo, G, Favaloro, A, Santoro, G, Bruschetta, D, Milardi, D, Micali, A, Di Mauro, D, Vermiglio, G, Anastasi, G, Trimarchi, F

“…The sarcoglycan complex consists of a group of single-pass transmembrane glycoproteins that are essential to maintain the integrity of muscle membranes. Any…”
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