Search Results - "Milanov, Ivan"
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Association between pain threshold and manifested pain assessed using a PD-specific pain scale in Parkinson's disease
Published in Frontiers in neurology (25-07-2024)“…The neurodegenerative process in Parkinson's disease (PD) affects both dopaminergic and non-dopaminergic structures, which determine the wide range of motor…”
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Translation, adaptation and validation of the Bulgarian version of the King’s Parkinson’s Disease Pain Scale
Published in BMC neurology (15-09-2021)“…Abstract Background The purpose of the present study was to translate and cross-culturally adapt the King’s Parkinson’s Disease Pain Scale (KPPS) into…”
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Update on the Management of Parkinson’s Disease for General Neurologists
Published in Parkinson's disease (2020)“…Management of Parkinson’s disease (PD) is complicated due to its progressive nature, the individual patient heterogeneity, and the wide range of signs,…”
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Thermodynamic Signatures of Blood Plasma Proteome in Neurodegenerative Pathologies
Published in International journal of molecular sciences (02-01-2023)“…Discovery of diagnostic biomarkers for age-related neurodegenerative pathologies (NDDs) is essential for accurate diagnosis, following disease progression and…”
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5
Clinical profile of levodopa-carbidopa-entacapone intestinal gel infusion in patients with advanced Parkinson’s disease
Published in Folia Medica (31-12-2023)“…Introduction : Parkinson’s disease in its advanced stage is a progressive condition that can be treated with levodopa. The long-term complications of this…”
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Consensus guidelines for botulinum toxin therapy: general algorithms and dosing tables for dystonia and spasticity
Published in Journal of Neural Transmission (01-03-2021)“…Botulinum toxin (BT) therapy is a complex and highly individualised therapy defined by treatment algorithms and injection schemes describing its target muscles…”
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Morphometry and Stiffness of Red Blood Cells-Signatures of Neurodegenerative Diseases and Aging
Published in International journal of molecular sciences (25-12-2021)“…Human red blood cells (RBCs) are unique cells with the remarkable ability to deform, which is crucial for their oxygen transport function, and which can be…”
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A new approach for objective monitoring of the pharmacological-treatment response in recurrent depressions
Published in Farmacija (20-06-2024)“…Depressive disorders are among the most important psychiatric problems. In everyday clinical practice, their symptoms and, respectively, their response to…”
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Structured Q1 headache services as the solution to the ill-health burden of headache: 1. Rationale and description
Published in Journal of headache and pain (01-12-2021)“…Abstract In countries where headache services exist at all, their focus is usually on specialist (tertiary) care. This is clinically and economically…”
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Efficacy and safety of adjunctive padsevonil in adults with drug‐resistant focal epilepsy: Results from two double‐blind, randomized, placebo‐controlled trials
Published in Epilepsia open (01-12-2022)“…Objective To characterize efficacy, safety/tolerability, and pharmacokinetics of padsevonil (PSL) administered concomitantly with ≤3 antiseizure medications…”
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Red Blood Cells' Thermodynamic Behavior in Neurodegenerative Pathologies and Aging
Published in Biomolecules (Basel, Switzerland) (12-10-2021)“…The main trend of current research in neurodegenerative diseases (NDDs) is directed towards the discovery of novel biomarkers for disease diagnostics and…”
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12
Platelets’ Nanomechanics and Morphology in Neurodegenerative Pathologies
Published in Biomedicines (01-09-2022)“…The imaging and force–distance curve modes of atomic force microscopy (AFM) are explored to compare the morphological and mechanical signatures of platelets…”
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13
Transient Mutism and Pathologic Laughter in the Course of Cerebellitis
Published in Pediatric neurology (01-07-2009)“…The phenomenon of cerebellar mutism with subsequent dysarthria is most commonly described as a part of posterior fossa syndrome after surgery for neoplasms in…”
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Enhancing and accelerating stroke treatment in Eastern European region: Methods and achievement of the ESO EAST program
Published in European stroke journal (01-06-2020)“…Introduction Despite the availability of prevention and therapies of stroke, their implementation in clinical practice, even of low-cost ones, remains poor. In…”
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Structured headache services as the solution to the ill-health burden of headache: 1. Rationale and description
Published in Journal of headache and pain (21-07-2021)“…In countries where headache services exist at all, their focus is usually on specialist (tertiary) care. This is clinically and economically inappropriate:…”
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Determination of plasma aminothiols by high performance liquid chromatography after precolumn derivatization with N-(2-acridonyl)maleimide
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-07-2008)“…Design, synthesis and properties of new derivatization reagent N-(2-acridonyl)-maleimide (MIAC) for thiol groups is presented. The reaction of MIAC with…”
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The impact of the comorbid seizure/epilepsy on the health related quality of life in people with multiple sclerosis: an international multicentric study
Published in Frontiers in immunology (2023)“…The health-related quality of life (HRQoL) of people with (Pw) multiple sclerosis (MS) is usually deteriorated. It has been recently suggested that…”
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Diagnostic value of combinations of symptoms of migraine and tension-type headache included in the diagnostic criteria for children and adolescents in the international classification of headache disorders 2nd edition
Published in Folia medica (Plovdiv) (01-07-2013)“…AIM: To suggest diagnostic combinations of symptoms for migraine and tension type headache (TTH), and for differentiation of overlapping headache (classified…”
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Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial
Published in Lancet neurology (01-01-2020)“…More than a third of patients with epilepsy are treatment resistant, and thus new, more effective therapies to achieve seizure freedom are needed. Cenobamate…”
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Inebilizumab for the treatment of neuromyelitis optica spectrum disorder (N-MOmentum): a double-blind, randomised placebo-controlled phase 2/3 trial
Published in The Lancet (British edition) (12-10-2019)“…No approved therapies exist for neuromyelitis optica spectrum disorder (NMOSD), a rare, relapsing, autoimmune, inflammatory disease of the CNS that causes…”
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