Search Results - "Milano, Stephane"

Selepressin, a novel selective V 1A receptor agonist: Effect on mesenteric flow and gastric mucosa perfusion in the endotoxemic rabbit by Milano, Stéphane P, Boucheix, Olivier B, Reinheimer, Torsten M

“…Intestinal or mesenteric ischemia generally leads to inflammation and injury, potentially developing hypoxia, causing cell death and tissue necrosis. This in…”
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Selepressin and Arginine Vasopressin Do Not Display Cardiovascular Risk in Atherosclerotic Rabbit by Boucheix, Olivier, Blakytny, Robert, Haroutunian, Gerard, Henriksson, Marie, Laporte, Regent, Milano, Stephane, Reinheimer, Torsten M

“…Septic shock remains associated with significant mortality rates. Arginine vasopressin (AVP) and analogs with V1A receptor agonist activity are increasingly…”
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Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies by Prior, Helen, Bottomley, Anna, Champéroux, Pascal, Cordes, Jason, Delpy, Eric, Dybdal, Noel, Edmunds, Nick, Engwall, Mike, Foley, Mike, Hoffmann, Michael, Kaiser, Robert, Meecham, Ken, Milano, Stéphane, Milne, Aileen, Nelson, Rick, Roche, Brian, Valentin, Jean-Pierre, Ward, Gemma, Chapman, Kathryn

“…The Safety Pharmacology Society (SPS) and National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs) conducted a survey and…”
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Assessment of thoracic impedance pneumography telemetry to ambulatory and restrained respiration measurement standards in the dog by Milano, Stephane P., Bpry, Christophe, Boucheix, Olivier, Lor, Isabelle, Dupuis, Celine, Moon, Boyce

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A wireless multisensor telemetry capsule for monitoring gastrointestinal function in the dog by Milano, Stephane P., Baudet, Stephane, Chalencon, Estelle, Lege, Philippe, Dupuis, Celine, Semler, Jack, Rhode, Bemina

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Telemetric assessment of minimally invasive arterial blood pressure in the minipig: Validation with isoprenaline by Baudet, Stéphane, Milano, Stéphane, Boucheix, Olivier, Chalencon, Estelle, Legé, Philippe, Bory, Christophe, Dupuis, Céline, Rieux, Eric, Tiesma, Scott

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Selepressin, a novel selective V1A receptor agonist: Effect on mesenteric flow and gastric mucosa perfusion in the endotoxemic rabbit by Milano, Stéphane P., Boucheix, Olivier B., Reinheimer, Torsten M.

“…•Arginine vasopressin is used as a supplementary vasopressor in severe hypotension.•Potential complications because arginine vasopressin is also a V2-receptor…”
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Yarrowia lipolytica Lipase 2 Is Stable and Highly Active in Test Meals and Increases Fat Absorption in an Animal Model of Pancreatic Exocrine Insufficiency by Aloulou, Ahmed, Schué, Mathieu, Puccinelli, Delphine, Milano, Stéphane, Delchambre, Chantal, Leblond, Yves, Laugier, René, Carrière, Frédéric

“…Background & Aims Pancreatic exocrine insufficiency (PEI) reduces pancreatic secretion of digestive enzymes, including lipases. Oral pancreatic enzyme…”
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Selepressin, a New V1A Receptor Agonist: Hemodynamic Comparison to Vasopressin in Dogs by Boucheix, Olivier B, Milano, Stéphane P, Henriksson, Marie, Reinheimer, Torsten M

“…ABSTRACTSelepressin is a new selective vasopressin V1a agonist for treatment of vasodilatory hypotension in shock. Its effect on coronary and aortic blood…”
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SUN-608 Juvenile Toxicity Study of Livoletide: A Peptide Analogue of Unacylated Ghrelin for the Treatment of Hyperphagia in Prader-Willi Syndrome by Xu, Howard, Spencer, Andrew, Milano, Stephane

“…Abstract Background: Prader-Willi syndrome (PWS) is a rare endocrine disorder characterized by hyperphagia and abnormal food-related behaviors that contribute…”
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ODP353 Sustained Suppression of IGF1 with AZP-3813, a Bicyclic 16-Amino Acid Peptide Antagonist of the Human Growth Hormone Receptor and a Potential New Treatment for Acromegaly by Culler, Michael, Milano, Stephane, Kurasaki, Haruaki, Tomiyama, Tatsuya, Reid, Patrick, van der Lely, Aart Jan

“…Abstract Medical treatment of acromegaly is based on either suppressing pituitary GH secretion or inhibiting GH action by preventing interaction with its…”
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A new noninvasive primate model for assessing potency and safety of botulinum toxins by Bory, Christophe, Boucheix, Olivier, Baudet, Stephane, Milano, Stephane

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Evaluation of iPrecio — Dual Channel pump: A safety pharmacology study case in the Gottingen Minipig by Bory, Christophe, Lege, Phillipe, Chalencon, Estelle, Milano, Stephane

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OR05-5 AZP-3404, a 9-Amino Acid Peptide Analog of Insulin-Like Growth Factor-Binding Protein 2, Reverses Insulin Resistance in Leptin-Deficient ob/ob Mice by Milano, Stephane, Delale, Thomas, Abribat, Thierry, Culler, Michael, van der Lely, Aart, Clemmons, David

“…Insulin-like growth factor-binding protein-2 (IGFBP-2), one of six highly-conserved binding proteins that modulate circulating IGF1, has significant regulatory…”
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MON-102 Nonclinical Development of AZP-531 (Livoletide): A Peptide Analog of Unacylated Ghrelin for the Treatment of Hyperphagia in Prader-Willi Syndrome by Milano, Stephane, Allas, Soraya, Cade, Didier, Briffaux, Jean-Paul, Spencer, Andrew

“…Prader-Willi syndrome (PWS) is a rare and complex endocrine disease characterized by hyperphagia and abnormal food-related behaviors that contribute to severe…”
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Vehicle Systems and Excipients Used in Minipig Drug Development Studies by Weaver, Margaret L., Grossi, Anette Blak, Schützsack, Jorgen, Parish, Joanna, Løgsted, Jeanet, Bøgh, Ingrid Brück, Cameron, David, Harvey, Warren, Festag, Matthias, Downes, Noel, Venturella, Silvana, Schlichtiger, Julia, Mhedhbi, Sofiene, Ross, Vanessa, Kissner, Thomas, Stark, Claudia, Milano, Stephane, Heining, Peter, Sanchez-Felix, Manual

“…Minipigs have been used for dermal drug development studies for decades, and they are currently more frequently considered as the second nonrodent species for…”
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Evaluation of iPrecio — Dual Channel pump: A safety pharmacology study case in the Cynomolgus Monkey by Bory, Christophe, Lege, Philippe, Chalencon, Estelle, Milano, Stephane, Gilbert, Kevin, Koeppel, Florence

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Electromyographic telemetry monitoring of SXN101959, a targeted secretion inhibitor (TSI) in the Sprague–Dawley rat by Milano, Stephane, Bory, Christophe, Dupuis, Celine, Chalencon, Estelle, Jones, Richard, Martinez, Alberto

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ATOSIBAN AND BARUSIBAN IMPROVED IMPAIRED ENDOMETRIAL BLOOD FLOW IN PREGNANT RABBITS by Arce, Joan-Carles, Cunego, Luciano, Perfetti, Paolo, Milano, Stéphane P., Reinheimer, Torsten M.

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8041 Eneboparatide, A Potent Stimulator Of Urinary Calcium Reabsorption, Induces Prolonged Renal Cortex Retention And PTH1 Receptor Signaling by Ravel, Guillaume, Datta, Rakesh, Milano, Stéphane, Ovize, Michel, Allas, Soraya, Aouadi, Myriam, Culler, Michael D

“…Abstract Disclosure: G. Ravel: Employee; Self; Amolyt Pharma. R. Datta: Consulting Fee; Self; Amolyt Pharma. S. Milano: Employee; Self; Amolyt Pharma. M…”
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