Search Results - "Milano, Kristin M"
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Pathway of Maternal Serotonin to the Human Embryo and Fetus
Published in Endocrinology (Philadelphia) (01-04-2018)“…Abstract Serotonin [5-hydroxytryptamine (5-HT)] is essential to intrauterine development, but its source is debated. We used immunocytochemistry to gauge 5-HT,…”
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Trophoblast inclusions and adverse birth outcomes
Published in PloS one (01-03-2022)“…Trophoblast inclusions-cross sections of abnormal trophoblast bilayer infoldings-have previously been associated with aneuploidy, placenta accreta, and…”
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YAP1 nuclear efflux and transcriptional reprograming follow membrane diminution upon VSV-G-induced cell fusion
Published in Nature communications (23-07-2021)“…Cells in many tissues, such as bone, muscle, and placenta, fuse into syncytia to acquire new functions and transcriptional programs. While it is known that…”
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Maternal respiratory SARS-CoV-2 infection in pregnancy is associated with a robust inflammatory response at the maternal-fetal interface
Published in Med (New York, N.Y. : Online) (14-05-2021)“…Pregnant women are at increased risk for severe outcomes from coronavirus disease 2019 (COVID-19), but the pathophysiology underlying this increased morbidity…”
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An experimental test of the ovulatory homolog model of female orgasm
Published in Proceedings of the National Academy of Sciences - PNAS (08-10-2019)“…The ovulatory homolog model of female orgasm posits that the neuro-endocrine mechanisms underlying female orgasm evolved from and are homologous to the…”
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Trophoblast inclusions in the human placenta: Identification, characterization, quantification, and interrelations of subtypes
Published in Placenta (Eastbourne) (01-01-2021)“…We sought to examine placentas enriched for trophoblast inclusions (TIs) in order to characterize, quantify, and examine the interrelations between subtypes of…”
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Trophoblast Inclusions Are Significantly Increased in the Placentas of Children in Families at Risk for Autism
Published in Biological psychiatry (1969) (01-08-2013)“…Background Gestation is a critical window for neurodevelopmental vulnerability. This study examined whether the presence of trophoblast inclusions (TIs) in the…”
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Type I interferons instigate fetal demise after Zika virus infection
Published in Science immunology (05-01-2018)“…Zika virus (ZIKV) infection during pregnancy is associated with adverse fetal outcomes, including microcephaly, growth restriction, and fetal demise. Type I…”
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Efficacy of telotristat ethyl: A peripheral tryptophan hydroxylase inhibitor that blocks serotonin biosynthesis against cultured liposarcoma, colon cancer, and cholangiocarcinoma cell lines
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e15602 Background: Serotonin (5-HT) is most often considered a neurotransmitter—but in reality its main function is to promote cell proliferation…”
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Trophoblast inclusions and adverse birth outcomes
Published in PloS one (01-01-2022)“…Objective Trophoblast inclusions—cross sections of abnormal trophoblast bilayer infoldings—have previously been associated with aneuploidy, placenta accreta,…”
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Journal Article