Search Results - "Milanesi, Laura Hautrive"
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Cyclooxygenase-2 inhibitors differentially attenuate pentylenetetrazol-induced seizures and increase of pro- and anti-inflammatory cytokine levels in the cerebral cortex and hippocampus of mice
Published in European journal of pharmacology (05-09-2017)“…Seizures increase prostaglandin and cytokine levels in the brain. However, it remains to be determined whether cyclooxygenase-2 (COX-2) derived metabolites…”
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Cannabidiol prevents amphetamine relapse and modulates D1- and D2-receptor levels in mesocorticolimbic brain areas of rats
Published in European neuropsychopharmacology (01-09-2021)“…•Cannabidiol (CBD) treatment prevented amphetamine (AMPH) relapse.•CBD treatment reduced anxiety-like behaviors following re-exposure to AMPH.•CBD reduced D1-…”
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(+)-Dehydrofukinone modulates membrane potential and delays seizure onset by GABAa receptor-mediated mechanism in mice
Published in Toxicology and applied pharmacology (01-10-2017)“…(+)-Dehydrofukinone (DHF), isolated from Nectandra grandiflora (Lauraceae) essential oil, induces sedation and anesthesia by modulation of GABAa receptors…”
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Effect of morphine on the persistence of long-term memory in rats
Published in Psychopharmacology (01-05-2015)“…Rationale Current evidence suggests that pharmacological manipulation around 12 h after training alters the persistence of long-term memory. However, no study…”
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Interesterified fat consumption since gestation decreases striatal dopaminergic targets levels and gdnf impairing locomotion of adult offspring
Published in Toxicology letters (15-03-2021)“…[Display omitted] •IF consumption modifies the brain fatty acids composition.•IF in early stages of life impairs sensorimotor development.•IF chronic…”
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Ferulic acid-loaded nanostructure prevents morphine reinstatement: the involvement of dopamine system, NRF2, and ΔFosB in the striatum brain area of rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-07-2023)“…Morphine is among the most powerful analgesics and pain-relieving agents. However, its addictive properties limit their medical use because patients may be…”
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Topiramate-chitosan nanoparticles prevent morphine reinstatement with no memory impairment: Dopaminergic and glutamatergic molecular aspects in rats
Published in Neurochemistry international (01-11-2021)“…Besides their clinical application, chronic misuse of opioids has often been associated to drug addiction due to their addictive properties, underlying…”
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Mediterranean X Western based diets: Opposite influences on opioid reinstatement
Published in Toxicology letters (15-06-2019)“…•Western diets evoke anxiety behaviors and activate HPA axis, favoring morphine addiction.•Western diets facilitate morphine withdrawal symptoms such as…”
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Can the dietary fat type facilitate memory impairments in adulthood? A comparative study between Mediterranean and Western-based diet in rats
Published in The Journal of nutritional biochemistry (01-09-2018)“…A balanced intake of fatty acids (FA) of both omega-6 (n-6) and -3 (n-3) series is essential for memory. The Mediterranean diet (MD), rich in n-3…”
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Toxicological aspects of interesterified fat: Brain damages in rats
Published in Toxicology letters (05-07-2017)“…[Display omitted] •In recent years interesterified fat (IF) has replaced trans fat in processed foods.•Dietary fatty acids are easily incorporated in neural…”
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