Search Results - "Milagro, F."

Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review by González-Becerra, K, Ramos-Lopez, O, Barrón-Cabrera, E, Riezu-Boj, J I, Milagro, F I, Martínez-López, E, Martínez, J A

“…Chronic illnesses like obesity, type 2 diabetes (T2D) and cardiovascular diseases, are worldwide major causes of morbidity and mortality. These pathological…”
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Editorial Special Issue: 2021 consortium for trans-pyrenean investigations on obesity and diabetes by Milagro, F. I., Capel, F., Carpéné, C.

“…This Special Issue of the Journal of Physiology and Biochemistry contains 7 contributions that have been elaborated in the context of the mini-network…”
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Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats by Etxeberria, U., Arias, N., Boqué, N., Macarulla, M.T., Portillo, M.P., Martínez, J.A., Milagro, F.I.

“…Diet-induced obesity is associated to an imbalance in the normal gut microbiota composition. Resveratrol and quercetin, widely known for their health…”
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DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients by Crujeiras, A. B., Diaz-Lagares, A., Sandoval, J., Milagro, F. I., Navas-Carretero, S., Carreira, M. C., Gomez, A., Hervas, D., Monteiro, M. P., Casanueva, F. F., Esteller, M., Martinez, J. A.

“…The characterization of the epigenetic changes within the obesity-related adipose tissue will provide new insights to understand this metabolic disorder, but…”
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Therapeutic perspectives of epigenetically active nutrients by Remely, M, Lovrecic, L, Garza, A L, Migliore, L, Peterlin, B, Milagro, F I, Martinez, A J, Haslberger, A G

“…Many nutrients are known for a wide range of activities in prevention and alleviation of various diseases. Recently, their potential role in regulating human…”
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Individuality and epigenetics in obesity by Campión, J, Milagro, F.I, Martínez, J.A

“…Excessive weight gain arises from the interactions among environmental factors, genetic predisposition and the individual behavior. However, it is becoming…”
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Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet by Cordero, P, Gomez-Uriz, A. M, Campion, J, Milagro, F. I, Martinez, J. A

“…Non-alcoholic fatty liver disease (NAFLD) is one of the first hepatic manifestations of metabolic syndrome, whose progression can lead to cirrhosis and hepatic…”
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Dietary factors, epigenetic modifications and obesity outcomes: Progresses and perspectives by Milagro, F.I., Mansego, M.L., De Miguel, C., Martínez, J.A.

“…Nutritional factors play a life-long role in human health. Indeed, there is growing evidence that one of the mechanisms by which nutrients and bioactive…”
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Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress by Gómez-Zorita, S., Fernández-Quintela, A., Macarulla, M. T., Aguirre, L., Hijona, E., Bujanda, L., Milagro, F., Martínez, J. A., Portillo, M. P.

“…Non-alcoholic fatty liver disease (NAFLD) is one of the most common manifestations of chronic liver disease worldwide. The aim of the present study was to…”
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Effect of hypoxia on caveolae-related protein expression and insulin signaling in adipocytes by Varela-Guruceaga, M., Milagro, F.I., Martínez, J.A., de Miguel, C.

“…Obesity is characterized by hypertrophy and hyperplasia of adipose tissue, which have been related to the development of hypoxia and insulin resistance. On the…”
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PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome‐wide methylation analysis by Samblas, M., Milagro, F. I., Mansego, M. L., Marti, A., Martinez, J. A.

“…Summary Background The global prevalence of childhood overweight and obesity has increased in the last years. Epigenetic dysregulation affecting gene…”
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Adherence to Mediterranean diet is associated with methylation changes in inflammation-related genes in peripheral blood cells by Arpón, A., Riezu-Boj, J. I., Milagro, F. I., Marti, A, Razquin, C., Martínez-González, M. A., Corella, D., Estruch, R., Casas, R., Fitó, M., Ros, E., Salas-Salvadó, J., Martínez, J. A.

“…Epigenetic processes, including DNA methylation, might be modulated by environmental factors such as the diet, which in turn have been associated with the…”
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DNA methylation of miRNA coding sequences putatively associated with childhood obesity by Mansego, M.L., Garcia‐Lacarte, M., Milagro, F.I., Marti, A., Martinez, J.A.

“…Summary Background Epigenetic mechanisms may be involved in obesity onset and its consequences. The aim of the present study was to evaluate whether DNA…”
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TNF-alpha promoter methylation in peripheral white blood cells: Relationship with circulating TNFα, truncal fat and n-6 PUFA intake in young women by Hermsdorff, H.H., Mansego, M.L., Campión, J., Milagro, F.I., Zulet, M.A., Martínez, J.A.

“…•Women with high truncal fat had lower methylation in some CpG sites of TNFα gene.•The CpG13 methylation level was negatively correlated with plasma TNFα…”
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Differential lipid metabolism outcomes associated with ADRB2 gene polymorphisms in response to two dietary interventions in overweight/obese subjects by Ramos-Lopez, O., Riezu-Boj, J.I., Milagro, F.I., Goni, L., Cuervo, M., Martinez, J.A.

“…A precise nutrigenetic management of hypercholesterolemia involves the understanding of the interactions between the individual's genotype and dietary intake…”
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Regulatory roles of miR-155 and let-7b on the expression of inflammation-related genes in THP-1 cells: effects of fatty acids by Marques-Rocha, J.L., Garcia-Lacarte, M., Samblas, M., Bressan, J., Martínez, J.A., Milagro, F.I.

“…The main aim of this investigation was to study the regulatory roles of let-7b and miR-155-3p on the expression of inflammation-associated genes in monocytes,…”
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Involvement of autophagy in the beneficial effects of resveratrol in hepatic steatosis treatment. A comparison with energy restriction by Milton-Laskibar, I, Aguirre, L, Etxeberria, U, Milagro, F I, Martínez, J A, Portillo, María P

“…Autophagy eliminates damaged cellular components. In the liver, it has been proposed that it mediates the breakdown of lipid droplets. This study aimed to…”
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High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats by Milagro, F. I., Campión, J., García-Díaz, D. F., Goyenechea, E., Paternain, L., Martínez, J. A.

“…Leptin is an adipokine involved in body weight and food intake regulation whose promoter region presents CpG islands that could be subject to dynamic…”
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Circadian Expression of Adiponectin and Its Receptors in Human Adipose Tissue by Gómez-Abellán, P, Gómez-Santos, C, Madrid, J. A, Milagro, F. I, Campion, J, Martínez, J. A, Ordovás, J. M, Garaulet, M

“…Adiponectin is one of the most clinically relevant cytokines associated with obesity. However, circadian rhythmicity of adiponectin in human adipose tissue…”
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Supplementation with methyl donors during lactation to high-fat-sucrose-fed dams protects offspring against liver fat accumulation when consuming an obesogenic diet by Cordero, P, Milagro, F I, Campion, J, Martinez, J A

“…Methyl donor supplementation has been reported to prevent obesity-induced liver fat accumulation in adult rats. We hypothesized that this protection could be…”
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