Search Results - "Milad, Mohammed"
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Sex differences in anxiety disorders: Interactions between fear, stress, and gonadal hormones
Published in Hormones and behavior (01-11-2015)“…This article is part of a Special Issue “SBN 2014”. Women are more vulnerable to stress- and fear-based disorders, such as anxiety and post-traumatic stress…”
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2
Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress
Published in Annual review of psychology (01-01-2012)“…The psychology of extinction has been studied for decades. Approximately 10 years ago, however, there began a concerted effort to understand the neural…”
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Temporal dynamics of relief in avoidance conditioning and fear extinction: Experimental validation and clinical relevance
Published in Behaviour research and therapy (01-09-2017)“…The learning principles that guide the acquisition and extinction of avoidance are not fully understood. We developed a novel paradigm to study the temporal…”
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4
Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways
Published in Trends in cognitive sciences (01-01-2012)“…Obsessive-compulsive disorder (OCD) affects approximately 2–3% of the population and is characterized by recurrent intrusive thoughts (obsessions) and…”
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The Study of Fear Extinction: Implications for Anxiety Disorders
Published in American Journal of Psychiatry (01-12-2011)“…In this review, the authors propose that the fear extinction model can be used as an experimental tool to cut across symptom dimensions of multiple anxiety…”
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Effects of Sleep on Memory for Conditioned Fear and Fear Extinction
Published in Psychological bulletin (01-07-2015)“…Learning and memory for extinction of conditioned fear is a basic mammalian mechanism for regulating negative emotion. Sleep promotes both the consolidation of…”
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7
Blockade of Estrogen by Hormonal Contraceptives Impairs Fear Extinction in Female Rats and Women
Published in Biological psychiatry (1969) (15-02-2013)“…Background Fear extinction is a laboratory model of fear inhibition and is the basis of exposure therapy for anxiety disorders. Emerging evidence from…”
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A causal model of post-traumatic stress disorder: disentangling predisposed from acquired neural abnormalities
Published in Trends in cognitive sciences (01-07-2013)“…Highlights • PTSD is triggered by well-delineated stressors, facilitating causal brain models. • Amygdala and dACC abnormalities confer vulnerability for…”
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Abnormal dynamic functional connectivity during fear extinction learning in PTSD and anxiety disorders
Published in Molecular psychiatry (01-04-2022)“…Examining the neural circuits of fear/threat extinction advanced our mechanistic understanding of several psychiatric disorders, including anxiety disorders…”
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Fear extinction learning modulates large-scale brain connectivity
Published in NeuroImage (Orlando, Fla.) (01-09-2021)“…Exploring the neural circuits of the extinction of conditioned fear is critical to advance our understanding of fear- and anxiety-related disorders. The field…”
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Prefrontal Cortex Stimulation Enhances Fear Extinction Memory in Humans
Published in Biological psychiatry (1969) (15-07-2018)“…Animal fear conditioning studies have illuminated neuronal mechanisms of learned associations between sensory stimuli and fear responses. In rats, brief…”
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Multimodal Categorical and Dimensional Approaches to Understanding Threat Conditioning and Its Extinction in Individuals With Anxiety Disorders
Published in JAMA psychiatry (Chicago, Ill.) (01-06-2020)“…The Research Domain Criteria project of the National Institute of Mental Health aims to guide neuropsychiatry toward precision medicine. Its inception was…”
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13
Unconditioned response to an aversive stimulus as predictor of response to conditioned fear and safety: A cross-species study
Published in Behavioural brain research (26-03-2021)“…Safety signals predict the non-occurrence of an aversive event, thereby inhibiting fear responses. Previous research has shown that conditioned safety learning…”
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14
Neuroscience of fear extinction: Implications for assessment and treatment of fear-based and anxiety related disorders
Published in Behaviour research and therapy (01-11-2014)“…Current exposure-based therapies aimed to reduce pathological fear and anxiety are now amongst the most effective interventions for trauma and anxiety related…”
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Biological studies of post-traumatic stress disorder
Published in Nature reviews. Neuroscience (01-11-2012)“…Key Points Perhaps the most well-replicated biological finding in post-traumatic stress disorder (PTSD) is higher autonomic (heart rate and skin conductance)…”
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The Role of the Orbitofrontal Cortex in Anxiety Disorders
Published in Annals of the New York Academy of Sciences (01-12-2007)“…: Advances in neuroimaging techniques over the past two decades have allowed scientists to investigate the neurocircuitry of anxiety disorders. Such research…”
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Deficits in conditioned fear extinction in obsessive-compulsive disorder and neurobiological changes in the fear circuit
Published in JAMA psychiatry (Chicago, Ill.) (01-06-2013)“…Obsessive-compulsive disorder (OCD) may be characterized by impaired self-regulation and behavioral inhibition. Elevated fear and anxiety are common…”
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Randomized controlled experimental study of hydrocortisone and D-cycloserine effects on fear extinction in PTSD
Published in Neuropsychopharmacology (New York, N.Y.) (01-10-2022)“…Fear extinction underlies prolonged exposure, one of the most well-studied treatments for posttraumatic stress disorder (PTSD). There has been increased…”
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Sleep and REM sleep disturbance in the pathophysiology of PTSD: the role of extinction memory
Published in Biology of mood & anxiety disorders (29-05-2015)“…Post-traumatic stress disorder (PTSD) is accompanied by disturbed sleep and an impaired ability to learn and remember extinction of conditioned fear. Following…”
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Gray matter associations with extinction-induced neural activation in patients with anxiety disorders
Published in Journal of psychiatric research (01-06-2023)“…The relationship between structural characteristics and extinction-induced brain activations in anxiety disorders (ANX) remains a space for greater…”
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