Search Results - "Milá, M"
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Respiratory syncytial virus-associated hospitalizations among children less than 24 months of age
Published in Pediatrics (Evanston) (01-08-2013)“…Respiratory syncytial virus (RSV) infection is a leading cause of hospitalization among infants. However, estimates of the RSV hospitalization burden have…”
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Human noroviruses' fondness for histo-blood group antigens
Published in Journal of virology (01-02-2015)“…Human noroviruses are the dominant cause of outbreaks of gastroenteritis around the world. Human noroviruses interact with the polymorphic human histo-blood…”
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Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases
Published in European journal of medicinal chemistry (05-10-2022)“…The RNA viruses SARS-CoV-2 and dengue pose a major threat to human health worldwide and their proteases (Mpro; NS2B/NS3) are considered as promising targets…”
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Impact of maternal immunization on influenza hospitalizations in infants
Published in American journal of obstetrics and gynecology (01-06-2011)“…We sought to determine whether maternal vaccination during pregnancy was associated with a reduced risk of laboratory-confirmed influenza hospitalizations in…”
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Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016
Published in Pediatrics (Evanston) (01-07-2020)“…Respiratory syncytial virus (RSV) is a major cause of hospitalized acute respiratory illness (ARI) among young children. With RSV vaccines and…”
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Peptide-β-lactam Inhibitors of Dengue and West Nile Virus NS2B-NS3 Protease Display Two Distinct Binding Modes
Published in Journal of medicinal chemistry (09-01-2020)“…The β-lactam ring represents a valuable moiety that can induce covalent binding of an inhibitor to its target. In this study, we explored di- and tripeptides…”
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Impaired Mitochondrial Function and Dynamics in the Pathogenesis of FXTAS
Published in Molecular neurobiology (01-11-2017)“…Mitochondrial involvement plays an important role in neurodegenerative diseases. At least one-third of adult carriers of a FMR1 premutation (55-200 CGG…”
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Active zone compaction correlates with presynaptic homeostatic potentiation
Published in Cell reports (Cambridge) (05-10-2021)“…Neurotransmitter release is stabilized by homeostatic plasticity. Presynaptic homeostatic potentiation (PHP) operates on timescales ranging from minute- to…”
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Determining the Seasonality of Respiratory Syncytial Virus in the United States: The Impact of Increased Molecular Testing
Published in The Journal of infectious diseases (01-08-2017)“…Background. In the United States, the seasonality of respiratory syncytial virus (RSV) has traditionally been defined on the basis of weeks during which…”
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Burden of Human Metapneumovirus Infection in Young Children
Published in The New England journal of medicine (14-02-2013)“…Human metapneumovirus (HMPV) was identified in 2001 as a cause of respiratory infection. In this study at three U.S. surveillance centers, HPMV was found in 6…”
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Human pineal physiology and functional significance of melatonin
Published in Frontiers in neuroendocrinology (01-09-2004)“…Descriptions of the pineal gland date back to antiquity, but its functions in humans are still poorly understood. In both diurnal and nocturnal vertebrates,…”
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Genetic and biochemical characterization of 16 acute intermittent porphyria cases with a high prevalence of the R173W mutation
Published in Journal of inherited metabolic disease (01-08-2006)“…Summary Acute intermittent porphyria (AIP) is a metabolic disease with a variable prevalence among different countries. In some areas of southern Europe it…”
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De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease
Published in ACS medicinal chemistry letters (14-02-2019)“…The Zika virus presents a major public health concern due to severe fetal neurological disorders associated with infections in pregnant women. In addition to…”
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Fragile X syndrome: An overview and update of the FMR1 gene
Published in Clinical genetics (01-02-2018)“…Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability and the leading form of the monogenic cause of autism. Fragile X mental…”
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Single-Molecule Localization Microscopy of Presynaptic Active Zones in Drosophila melanogaster after Rapid Cryofixation
Published in International journal of molecular sciences (21-01-2023)“…Single-molecule localization microscopy (SMLM) greatly advances structural studies of diverse biological tissues. For example, presynaptic active zone (AZ)…”
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Changes in Influenza and Other Respiratory Virus Activity During the COVID-19 Pandemic - United States, 2020-2021
Published in MMWR. Morbidity and mortality weekly report (23-07-2021)“…The COVID-19 pandemic and subsequent implementation of nonpharmaceutical interventions (e.g., cessation of global travel, mask use, physical distancing, and…”
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Changes in influenza and other respiratory virus activity during the COVID‐19 pandemic—United States, 2020–2021
Published in American journal of transplantation (01-10-2021)Get full text
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Beyond Basicity: Discovery of Nonbasic DENV‑2 Protease Inhibitors with Potent Activity in Cell Culture
Published in Journal of medicinal chemistry (22-04-2021)“…The viral serine protease NS2B-NS3 is one of the promising targets for drug discovery against dengue virus and other flaviviruses. The molecular recognition…”
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Plate osteosynthesis combined with bone cement provides the highest stability for tibial head depression fractures under high loading conditions
Published in Scientific reports (14-09-2022)“…Older patients sustaining tibial head depression fractures often cannot follow the post-operative rehabilitation protocols with partial weight-bearing of the…”
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Early-life immunomodulation by carvacrol delivered in ovo in broiler chickens
Published in Poultry science (01-12-2024)“…In the first 2 wk after hatching, broiler chickens are vulnerable to enteric pathogens due to underdeveloped gastrointestinal and immune systems. Carvacrol has…”
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