Search Results - "Milá, M"

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    Human noroviruses' fondness for histo-blood group antigens by Singh, Bishal K, Leuthold, Mila M, Hansman, Grant S

    Published in Journal of virology (01-02-2015)
    “…Human noroviruses are the dominant cause of outbreaks of gastroenteritis around the world. Human noroviruses interact with the polymorphic human histo-blood…”
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    Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases by Kühl, Nikos, Lang, Johannes, Leuthold, Mila M., Klein, Christian D.

    Published in European journal of medicinal chemistry (05-10-2022)
    “…The RNA viruses SARS-CoV-2 and dengue pose a major threat to human health worldwide and their proteases (Mpro; NS2B/NS3) are considered as promising targets…”
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    Peptide-β-lactam Inhibitors of Dengue and West Nile Virus NS2B-NS3 Protease Display Two Distinct Binding Modes by Dražić, Tonko, Kopf, Sara, Corridan, James, Leuthold, Mila M, Bertoša, Branimir, Klein, Christian D

    Published in Journal of medicinal chemistry (09-01-2020)
    “…The β-lactam ring represents a valuable moiety that can induce covalent binding of an inhibitor to its target. In this study, we explored di- and tripeptides…”
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    Impaired Mitochondrial Function and Dynamics in the Pathogenesis of FXTAS by Alvarez-Mora, M. I., Rodriguez-Revenga, L., Madrigal, I., Guitart-Mampel, M., Garrabou, G., Milà, M.

    Published in Molecular neurobiology (01-11-2017)
    “…Mitochondrial involvement plays an important role in neurodegenerative diseases. At least one-third of adult carriers of a FMR1 premutation (55-200 CGG…”
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    Active zone compaction correlates with presynaptic homeostatic potentiation by Mrestani, Achmed, Pauli, Martin, Kollmannsberger, Philip, Repp, Felix, Kittel, Robert J., Eilers, Jens, Doose, Sören, Sauer, Markus, Sirén, Anna-Leena, Heckmann, Manfred, Paul, Mila M.

    Published in Cell reports (Cambridge) (05-10-2021)
    “…Neurotransmitter release is stabilized by homeostatic plasticity. Presynaptic homeostatic potentiation (PHP) operates on timescales ranging from minute- to…”
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    Determining the Seasonality of Respiratory Syncytial Virus in the United States: The Impact of Increased Molecular Testing by Midgley, Claire M., Haynes, Amber K., Baumgardner, Jason L., Chommanard, Christina, Demas, Sara W., Prill, Mila M., Abedi, Glen R., Curns, Aaron T., Watson, John T., Gerber, Susan I.

    Published in The Journal of infectious diseases (01-08-2017)
    “…Background. In the United States, the seasonality of respiratory syncytial virus (RSV) has traditionally been defined on the basis of weeks during which…”
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    Burden of Human Metapneumovirus Infection in Young Children by Edwards, Kathryn M, Zhu, Yuwei, Griffin, Marie R, Weinberg, Geoffrey A, Hall, Caroline B, Szilagyi, Peter G, Staat, Mary A, Iwane, Marika, Prill, Mila M, Williams, John V

    Published in The New England journal of medicine (14-02-2013)
    “…Human metapneumovirus (HMPV) was identified in 2001 as a cause of respiratory infection. In this study at three U.S. surveillance centers, HPMV was found in 6…”
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    Human pineal physiology and functional significance of melatonin by Macchi, M. Mila, Bruce, Jeffrey N.

    Published in Frontiers in neuroendocrinology (01-09-2004)
    “…Descriptions of the pineal gland date back to antiquity, but its functions in humans are still poorly understood. In both diurnal and nocturnal vertebrates,…”
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    Genetic and biochemical characterization of 16 acute intermittent porphyria cases with a high prevalence of the R173W mutation by To‐Figueras, J., Badenas, C., Carrera, C., Muñoz, C., Milá, M., Lecha, M., Herrero, C.

    Published in Journal of inherited metabolic disease (01-08-2006)
    “…Summary Acute intermittent porphyria (AIP) is a metabolic disease with a variable prevalence among different countries. In some areas of southern Europe it…”
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    De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease by Nitsche, Christoph, Passioura, Toby, Varava, Paul, Mahawaththa, Mithun C, Leuthold, Mila M, Klein, Christian D, Suga, Hiroaki, Otting, Gottfried

    Published in ACS medicinal chemistry letters (14-02-2019)
    “…The Zika virus presents a major public health concern due to severe fetal neurological disorders associated with infections in pregnant women. In addition to…”
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    Fragile X syndrome: An overview and update of the FMR1 gene by Mila, M., Alvarez‐Mora, M.I., Madrigal, I., Rodriguez‐Revenga, L.

    Published in Clinical genetics (01-02-2018)
    “…Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability and the leading form of the monogenic cause of autism. Fragile X mental…”
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    Single-Molecule Localization Microscopy of Presynaptic Active Zones in Drosophila melanogaster after Rapid Cryofixation by Mrestani, Achmed, Lichter, Katharina, Sirén, Anna-Leena, Heckmann, Manfred, Paul, Mila M, Pauli, Martin

    “…Single-molecule localization microscopy (SMLM) greatly advances structural studies of diverse biological tissues. For example, presynaptic active zone (AZ)…”
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    Beyond Basicity: Discovery of Nonbasic DENV‑2 Protease Inhibitors with Potent Activity in Cell Culture by Kühl, Nikos, Leuthold, Mila M, Behnam, Mira A. M, Klein, Christian D

    Published in Journal of medicinal chemistry (22-04-2021)
    “…The viral serine protease NS2B-NS3 is one of the promising targets for drug discovery against dengue virus and other flaviviruses. The molecular recognition…”
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    Plate osteosynthesis combined with bone cement provides the highest stability for tibial head depression fractures under high loading conditions by Heilig, Philipp, Faerber, Lars-Christopher, Paul, Mila M., Kupczyk, Eva, Meffert, Rainer H., Jordan, Martin C., Hoelscher-Doht, Stefanie

    Published in Scientific reports (14-09-2022)
    “…Older patients sustaining tibial head depression fractures often cannot follow the post-operative rehabilitation protocols with partial weight-bearing of the…”
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    Early-life immunomodulation by carvacrol delivered in ovo in broiler chickens by Meijer, Mila M.Y., Brand, Henry van den, Palmieri, Chiara, Niknafs, Shahram, Khaskheli, Asad A., Roura, Eugeni

    Published in Poultry science (01-12-2024)
    “…In the first 2 wk after hatching, broiler chickens are vulnerable to enteric pathogens due to underdeveloped gastrointestinal and immune systems. Carvacrol has…”
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