Search Results - "Mikusevic, Vedrana"
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Structural basis of proton-coupled potassium transport in the KUP family
Published in Nature communications (31-01-2020)“…Potassium homeostasis is vital for all organisms, but is challenging in single-celled organisms like bacteria and yeast and immobile organisms like plants that…”
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2
Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance
Published in eLife (07-06-2022)“…The acidic luminal pH of lysosomes, maintained within a narrow range, is essential for proper degrative function of the organelle and is generated by the…”
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3
A channel profile report of the unusual K + channel KtrB
Published in The Journal of general physiology (02-12-2019)“…KtrAB is a key player in bacterial K uptake required for K homeostasis and osmoadaptation. The system is unique in structure and function. It consists of the K…”
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4
Helical jackknives control the gates of the double-pore K + uptake system KtrAB
Published in eLife (16-05-2017)“…Ion channel gating is essential for cellular homeostasis and is tightly controlled. In some eukaryotic and most bacterial ligand-gated K channels, RCK domains…”
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5
The effects of disease-causing ClC-7 mutations on lysosomal pH
Published in Biophysical journal (10-02-2023)Get full text
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6
Functional diversity of the superfamily of K⁺ transporters to meet various requirements
Published in Biological chemistry (01-09-2015)“…The superfamily of K+ transporters unites proteins from plants, fungi, bacteria, and archaea that translocate K+ and/or Na+ across membranes. These proteins…”
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7
Native mass spectrometry goes more native: investigation of membrane protein complexes directly from SMALPs
Published in Chemical communications (Cambridge, England) (04-12-2018)“…Other than more widely used methods, the use of styrene maleic acid allows the direct extraction of membrane proteins from the lipid bilayer into SMALPs…”
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8
The chloride antiporter CLCN7 is a modifier of lysosome dysfunction in FIG4 and VAC14 mutants
Published in PLoS genetics (26-06-2023)“…The phosphatase FIG4 and the scaffold protein VAC14 function in the biosynthesis of PI(3,5)P2, a signaling lipid that inhibits the lysosomal chloride…”
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9
Tonic inhibition of the chloride/proton antiporter ClC-7 by PIP2 is crucial for lysosomal pH maintenance
Published in eLife (07-06-2022)“…The acidic luminal pH of lysosomes, maintained within a narrow range, is essential for proper degrative function of the organelle and is generated by the…”
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10
Allosteric Control of the K+ Uptake System KtrAB
Published in Biophysical journal (02-02-2018)Get full text
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11
Helical jackknives control the gates of the double-pore K.sup.+ uptake system KtrAB
Published in eLife (16-05-2017)“…Ion channel gating is essential for cellular homeostasis and is tightly controlled. In some eukaryotic and most bacterial ligand-gated K.sup.+ channels, RCK…”
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12
Grenzgänger – Proteine zwischen Kaliumtransportern und -kanälen
Published in Biospektrum (01-02-2019)“…Channels and transporters are traditionally considered as two completely different entities. However, members of the superfamily of potassium transporters…”
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