Search Results - "Mikusevic, Vedrana"

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  1. 1

    Structural basis of proton-coupled potassium transport in the KUP family by Tascón, Igor, Sousa, Joana S., Corey, Robin A., Mills, Deryck J., Griwatz, David, Aumüller, Nadine, Mikusevic, Vedrana, Stansfeld, Phillip J., Vonck, Janet, Hänelt, Inga

    Published in Nature communications (31-01-2020)
    “…Potassium homeostasis is vital for all organisms, but is challenging in single-celled organisms like bacteria and yeast and immobile organisms like plants that…”
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  2. 2

    Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance by Leray, Xavier, Hilton, Jacob K, Nwangwu, Kamsi, Becerril, Alissa, Mikusevic, Vedrana, Fitzgerald, Gabriel, Amin, Anowarul, Weston, Mary R, Mindell, Joseph A

    Published in eLife (07-06-2022)
    “…The acidic luminal pH of lysosomes, maintained within a narrow range, is essential for proper degrative function of the organelle and is generated by the…”
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    Journal Article
  3. 3

    A channel profile report of the unusual K + channel KtrB by Mikušević, Vedrana, Schrecker, Marina, Kolesova, Natalie, Patiño-Ruiz, Miyer, Fendler, Klaus, Hänelt, Inga

    Published in The Journal of general physiology (02-12-2019)
    “…KtrAB is a key player in bacterial K uptake required for K homeostasis and osmoadaptation. The system is unique in structure and function. It consists of the K…”
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  4. 4

    Helical jackknives control the gates of the double-pore K + uptake system KtrAB by Diskowski, Marina, Mehdipour, Ahmad Reza, Wunnicke, Dorith, Mills, Deryck J, Mikusevic, Vedrana, Bärland, Natalie, Hoffmann, Jan, Morgner, Nina, Steinhoff, Heinz-Jürgen, Hummer, Gerhard, Vonck, Janet, Hänelt, Inga

    Published in eLife (16-05-2017)
    “…Ion channel gating is essential for cellular homeostasis and is tightly controlled. In some eukaryotic and most bacterial ligand-gated K channels, RCK domains…”
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  5. 5
  6. 6

    Functional diversity of the superfamily of K⁺ transporters to meet various requirements by Diskowski, Marina, Mikusevic, Vedrana, Stock, Charlott, Hänelt, Inga

    Published in Biological chemistry (01-09-2015)
    “…The superfamily of K+ transporters unites proteins from plants, fungi, bacteria, and archaea that translocate K+ and/or Na+ across membranes. These proteins…”
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  7. 7
  8. 8

    The chloride antiporter CLCN7 is a modifier of lysosome dysfunction in FIG4 and VAC14 mutants by Cao, Xu, Lenk, Guy M, Mikusevic, Vedrana, Mindell, Joseph A, Meisler, Miriam H

    Published in PLoS genetics (26-06-2023)
    “…The phosphatase FIG4 and the scaffold protein VAC14 function in the biosynthesis of PI(3,5)P2, a signaling lipid that inhibits the lysosomal chloride…”
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  9. 9

    Tonic inhibition of the chloride/proton antiporter ClC-7 by PIP2 is crucial for lysosomal pH maintenance by Leray, Xavier, Hilton, Jacob K, Nwangwu, Kamsi, Becerril, Alissa, Mikusevic, Vedrana, Fitzgerald, Gabriel, Amin, Anowarul, Weston, Mary R, Mindell, Joseph A

    Published in eLife (07-06-2022)
    “…The acidic luminal pH of lysosomes, maintained within a narrow range, is essential for proper degrative function of the organelle and is generated by the…”
    Get full text
    Journal Article
  10. 10
  11. 11

    Helical jackknives control the gates of the double-pore K.sup.+ uptake system KtrAB by Diskowski, Marina, Mehdipour, Ahmad Reza, Wunnicke, Dorith, Mills, Deryck J, Mikusevic, Vedrana, Bärland, Natalie, Hoffmann, Jan, Morgner, Nina, Steinhoff, Heinz-Jürgen, Hummer, Gerhard, Vonck, Janet, Hänelt, Inga

    Published in eLife (16-05-2017)
    “…Ion channel gating is essential for cellular homeostasis and is tightly controlled. In some eukaryotic and most bacterial ligand-gated K.sup.+ channels, RCK…”
    Get full text
    Journal Article
  12. 12

    Grenzgänger – Proteine zwischen Kaliumtransportern und -kanälen by Stock, Charlott, Schrecker, Marina, Mikusevic, Vedrana, Hänelt, Inga

    Published in Biospektrum (01-02-2019)
    “…Channels and transporters are traditionally considered as two completely different entities. However, members of the superfamily of potassium transporters…”
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    Journal Article