Search Results - "Mikulis, D J"

Cerebrovascular reactivity mapping: an evolving standard for clinical functional imaging by Pillai, J J, Mikulis, D J

“…This review article explains the methodology of breath-hold cerebrovascular reactivity mapping, both in terms of acquisition and analysis, and reviews…”
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Measuring cerebrovascular reactivity: what stimulus to use? by Fierstra, J., Sobczyk, O., Battisti‐Charbonney, A., Mandell, D. M., Poublanc, J., Crawley, A. P., Mikulis, D. J., Duffin, J., Fisher, J. A.

“…Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory or vasoconstrictive stimulus. Measuring variations of…”
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A conceptual model for CO2-induced redistribution of cerebral blood flow with experimental confirmation using BOLD MRI by Sobczyk, O., Battisti-Charbonney, A., Fierstra, J., Mandell, D.M., Poublanc, J., Crawley, A.P., Mikulis, D.J., Duffin, J., Fisher, J.A.

“…Cerebrovascular reactivity (CVR) is the change in cerebral blood flow (CBF) in response to a change in a vasoactive stimulus. Paradoxical reductions in CBF in…”
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Intracranial arterial wall imaging using high-resolution 3-tesla contrast-enhanced MRI by SWARTZ, R. H, BHUTA, S. S, MIKULIS, D. J, FARB, R. I, AGID, R, WILLINSKY, R. A, TERBRUGGE, K. G, BUTANY, J, WASSERMAN, B. A, JOHNSTONE, D. M, SILVER, F. L

“…Conventional arterial imaging focuses on the vessel lumen but lacks specificity because different pathologies produce similar luminal defects. Wall imaging can…”
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Idiopathic intracranial hypertension: The prevalence and morphology of sinovenous stenosis by FARB, R. I, VANEK, I, SCOTT, J. N, MIKULIS, D. J, WILLINSKY, R. A, TOMLINSON, G, TERBRUGGE, K. G

“…To determine the prevalence and nature of sinovenous obstruction in idiopathic intracranial hypertension (IIH) using auto-triggered elliptic-centric-ordered…”
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Cognitive modulation of pain-related brain responses depends on behavioral strategy by Seminowicz, D.A., Mikulis, D.J., Davis, K.D.

“…Interactions of pain and cognition have been studied in humans and animals previously, but the relationship between such behavioral interactions and brain…”
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The dynamics of cerebrovascular reactivity shown with transfer function analysis by Duffin, J., Sobczyk, O., Crawley, A.P., Poublanc, J., Mikulis, D.J., Fisher, J.A.

“…Cerebrovascular reactivity (CVR) is often defined as the increase in cerebral blood flow (CBF) produced by an increase in carbon dioxide (CO2) and may be used…”
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Idiopathic intracranial hypertension : the validity of cross-sectional neuroimaging signs by AGID, R, FARB, R. I, WILLINSKY, R. A, MIKULIS, D. J, TOMLINSON, G

“…The aim of this study was to evaluate the accuracy of previously reported neuroimaging signs in establishing or excluding the diagnosis of idiopathic…”
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Quantitative Measurement of Cerebrovascular Reactivity by Blood Oxygen Level-Dependent MR Imaging in Patients with Intracranial Stenosis: Preoperative Cerebrovascular Reactivity Predicts the Effect of Extracranial-Intracranial Bypass Surgery by MANDELL, D. M, HAN, J. S, POUBLANC, J, CRAWLEY, A. P, FIERSTRA, J, TYMIANSKI, M, FISHER, J. A, MIKULIS, D. J

“…CVR is a measure of cerebral hemodynamic impairment. A recently validated technique quantifies CVR by using a precise CO(2) vasodilatory stimulus and BOLD MR…”
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Abnormal forebrain activity in functional bowel disorder patients with chronic pain by KWAN, C. L, DIAMANT, N. E, POPE, G, MIKULA, K, MIKULIS, D. J, DAVIS, K. D

“…Abnormal cortical pain responses in patients with fibromyalgia and conversion disorder raise the possibility of a neurobiologic basis underlying so-called…”
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Altered central somatosensory processing in chronic pain patients with hysterical anesthesia by MAILIS-GAGNON, A, GIANNOYLIS, I, DOWNAR, J, KWAN, C. L, MIKULIS, D. J, CRAWLEY, A. P, NICHOLSON, K, DAVIS, K. D

“…The authors hypothesized that central factors may underlie sensory deficits in patients with nondermatomal somatosensory deficits (NDSD) and that functional…”
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Somatosensory cortical atrophy after spinal cord injury : A voxel-based morphometry study by JURKIEWICZ, M. T, CRAWLEY, A. P, VERRIER, M. C, FEHLINGS, M. G, MIKULIS, D. J

“…The authors used voxel-based morphometry to compare sensorimotor cortical gray and white matter volume on structural MR images of a group of 17 individuals…”
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The Venous Distension Sign: A Diagnostic Sign of Intracranial Hypotension at MR Imaging of the Brain by Farb, R.I, Forghani, R, Lee, S.K, Mikulis, D.J, Agid, R

“…Patients with intracranial hypotension (IH) demonstrate intracranial venous enlargement with a characteristic change in contour of the transverse sinus seen on…”
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Recombinant Tissue Plasminogen Activator Increases Blood-Brain Barrier Disruption in Acute Ischemic Stroke: An MR Imaging Permeability Study by Kassner, A, Roberts, T.P.L, Moran, B, Silver, F.L, Mikulis, D.J

“…Although thrombolytic therapy (recombinant tissue plasminogen activator [rtPA]) represents an important step forward in acute ischemic stroke (AIS) management,…”
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Quantification of Cerebrovascular Reactivity by Blood Oxygen Level-Dependent MR Imaging and Correlation with Conventional Angiography in Patients with Moyamoya Disease by HEYN, C, POUBLANC, J, CRAWLEY, A, MANDELL, D, HAN, J. S, TYMIANSKI, M, TERBRUGGE, K, FISHER, J. A, MIKULIS, D. J

“…BOLD MR imaging combined with a technique for precision control of end-tidal pCO(2) was used to produce quantitative maps of CVR in patients with Moyamoya…”
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Chasing chasing the dragon with MRI : leukoencephalopathy in drug abuse by BARTLETT, E, MIKULIS, D. J

“…Spongiform leukoencephalopathy is a rare complication from inhalation of heated heroin vapour, a practice called "chasing the dragon". The MRI findings are…”
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Contrast-Enhanced MR Imaging in Acute Ischemic Stroke: T2 Measures of Blood-Brain Barrier Permeability and Their Relationship to T1 Estimates and Hemorrhagic Transformation by THORNHILL, R. E, CHEN, S, RAMMO, W, MIKULIS, D. J, KASSNER, A

“…rtPA is an effective treatment for AIS, yet it is substantially underused due to the increased risk of HT. Recent work suggests that permeability-related…”
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Mapping white matter diffusion and cerebrovascular reactivity in carotid occlusive disease by CONKLIN, J, FIERSTRA, J, CRAWLEY, A. P, HAN, J. S, POUBLANC, J, SILVER, F. L, TYMIANSKI, M, FISHER, J. A, MANDELL, D. M, MIKULIS, D. J

“…To characterize the relationship between cerebrovascular reactivity (CVR) and white matter (WM) diffusion in patients with internal carotid artery (ICA)…”
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Perceptual Illusion of "Paradoxical Heat" Engages the Insular Cortex by Davis, K. D, Pope, G. E, Crawley, A. P, Mikulis, D. J

“…Departments of 1 Surgery and 2 Medical Imaging, University of Toronto; and 3 Toronto Western Research Institute, Toronto Western Hospital, University Health…”
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Intracranial Vessel Wall MRI: Principles and Expert Consensus Recommendations of the American Society of Neuroradiology by Mandell, D M, Mossa-Basha, M, Qiao, Y, Hess, C P, Hui, F, Matouk, C, Johnson, M H, Daemen, M J A P, Vossough, A, Edjlali, M, Saloner, D, Ansari, S A, Wasserman, B A, Mikulis, D J

“…Intracranial vessel wall MR imaging is an adjunct to conventional angiographic imaging with CTA, MRA, or DSA. The technique has multiple potential uses in the…”
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