Search Results - "Mikosz, Andrew M"
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Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture
Published in Nature (London) (08-08-2013)“…A new approach has been developed in order to achieve the stepwise differentiation of inner ear sensory epithelia from mouse embryonic stem cells in a…”
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Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells
Published in Nature communications (24-05-2016)“…Inner ear sensory epithelia contain mechanosensitive hair cells that transmit information to the brain through innervation with bipolar neurons. Mammalian hair…”
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MicroRNA-126-3p Inhibits Angiogenic Function of Human Lung Microvascular Endothelial Cells via LAT1 (L-Type Amino Acid Transporter 1)-Mediated mTOR (Mammalian Target of Rapamycin) Signaling
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2020)“…OBJECTIVE:MicroRNA-126-3p (miR-126) is required for angiogenesis during organismal development or the repair of injured arterial vasculature. The role of…”
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Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice
Published in American journal of physiology. Lung cellular and molecular physiology (01-03-2019)“…Proapoptotic and monocyte chemotactic endothelial monocyte-activating protein 2 (EMAPII) is released extracellularly during cigarette smoke (CS) exposure. We…”
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Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury
Published in Respiratory research (31-05-2018)“…Several inflammatory lung diseases display abundant presence of hyaluronic acid (HA) bound to heavy chains (HC) of serum protein inter-alpha-inhibitor (IαI) in…”
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Role of Glucosylceramide in Lung Endothelial Cell Fate and Emphysema
Published in American journal of respiratory and critical care medicine (01-11-2019)“…The loss of pulmonary endothelial cells in emphysema is associated with increased lung ceramide. Ceramide perturbations may cause adaptive alterations in other…”
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Altered Macrophage Function Associated with Crystalline Lung Inflammation in Acid Sphingomyelinase Deficiency
Published in American journal of respiratory cell and molecular biology (01-05-2021)“…Deficiency of ASM (acid sphingomyelinase) causes the lysosomal storage Niemann-Pick disease (NPD). Patients with NPD type B may develop progressive…”
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