Search Results - "Mikosz, Andrew"

Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture by Koehler, Karl R., Mikosz, Andrew M., Molosh, Andrei I., Patel, Dharmeshkumar, Hashino, Eri

“…A new approach has been developed in order to achieve the stepwise differentiation of inner ear sensory epithelia from mouse embryonic stem cells in a…”
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Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells by Liu, Xiao-Ping, Koehler, Karl R., Mikosz, Andrew M., Hashino, Eri, Holt, Jeffrey R.

“…Inner ear sensory epithelia contain mechanosensitive hair cells that transmit information to the brain through innervation with bipolar neurons. Mammalian hair…”
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MicroRNA-126-3p Inhibits Angiogenic Function of Human Lung Microvascular Endothelial Cells via LAT1 (L-Type Amino Acid Transporter 1)-Mediated mTOR (Mammalian Target of Rapamycin) Signaling by Cao, Danting, Mikosz, Andrew M., Ringsby, Alexandra J., Anderson, Kelsey C., Beatman, Erica L., Koike, Kengo, Petrache, Irina

“…OBJECTIVE:MicroRNA-126-3p (miR-126) is required for angiogenesis during organismal development or the repair of injured arterial vasculature. The role of…”
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Structural and functional characterization of endothelial microparticles released by cigarette smoke by Serban, Karina A., Rezania, Samin, Petrusca, Daniela N., Poirier, Christophe, Cao, Danting, Justice, Matthew J., Patel, Milan, Tsvetkova, Irina, Kamocki, Krzysztof, Mikosz, Andrew, Schweitzer, Kelly S., Jacobson, Sean, Cardoso, Angelo, Carlesso, Nadia, Hubbard, Walter C., Kechris, Katerina, Dragnea, Bogdan, Berdyshev, Evgeny V., McClintock, Jeanette, Petrache, Irina

“…Circulating endothelial microparticles (EMPs) are emerging as biomarkers of chronic obstructive pulmonary disease (COPD) in individuals exposed to cigarette…”
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Role of Glucosylceramide in Lung Endothelial Cell Fate and Emphysema by Koike, Kengo, Berdyshev, Evgeny V, Mikosz, Andrew M, Bronova, Irina A, Bronoff, Anna S, Jung, John P, Beatman, Erica L, Ni, Kevin, Cao, Danting, Scruggs, April K, Serban, Karina A, Petrache, Irina

“…The loss of pulmonary endothelial cells in emphysema is associated with increased lung ceramide. Ceramide perturbations may cause adaptive alterations in other…”
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Subcutaneous administration of neutralizing antibodies to endothelial monocyte-activating protein II attenuates cigarette smoke-induced lung injury in mice by Koike, Kengo, Beatman, Erica L, Schweitzer, Kelly S, Justice, Matthew J, Mikosz, Andrew M, Ni, Kevin, Clauss, Matthias A, Petrache, Irina

“…Proapoptotic and monocyte chemotactic endothelial monocyte-activating protein 2 (EMAPII) is released extracellularly during cigarette smoke (CS) exposure. We…”
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Altered Macrophage Function Associated with Crystalline Lung Inflammation in Acid Sphingomyelinase Deficiency by Poczobutt, Joanna M, Mikosz, Andrew M, Poirier, Christophe, Beatman, Erica L, Serban, Karina A, Gally, Fabienne, Cao, Danting, McCubbrey, Alexandra L, Cornell, Christina F, Schweitzer, Kelly S, Berdyshev, Evgeny V, Bronova, Irina A, Paris, François, Petrache, Irina

“…Deficiency of ASM (acid sphingomyelinase) causes the lysosomal storage Niemann-Pick disease (NPD). Patients with NPD type B may develop progressive…”
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Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury by Ni, Kevin, Gill, Amar, Tseng, Victor, Mikosz, Andrew M, Koike, Kengo, Beatman, Erica L, Xu, Cassie Y, Cao, Danting, Gally, Fabienne, Mould, Kara J, Serban, Karina A, Schweitzer, Kelly S, March, Keith L, Janssen, William J, Nozik-Grayck, Eva, Garantziotis, Stavros, Petrache, Irina

“…Several inflammatory lung diseases display abundant presence of hyaluronic acid (HA) bound to heavy chains (HC) of serum protein inter-alpha-inhibitor (IαI) in…”
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Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure by Serban, Karina A, Petrusca, Daniela N, Mikosz, Andrew, Poirier, Christophe, Lockett, Angelia D, Saint, Lauren, Justice, Matthew J, Twigg, 3rd, Homer L, Campos, Michael A, Petrache, Irina

“…Cigarette smoking (CS), the main risk factor for COPD (chronic obstructive pulmonary disease) in developed countries, decreases alveolar macrophages (AM)…”
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MicroRNA-126-3p inhibits angiogenic function of human lung microvascular endothelial cell via LAT1-mediated mTOR signaling by Cao, Danting, Mikosz, Andrew M., Ringsby, Alexandra J., Anderson, Kelsey C., Beatman, Erica L., Koike, Kengo, Petrache, Irina

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Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions by Mikosz, Andrew, Ni, Kevin, Gally, Fabienne, Pratte, Katherine A, Winfree, Seth, Lin, Qiong, Echelman, Isabelle, Wetmore, Brianna, Cao, Danting, Justice, Matthew J, Sandhaus, Robert A, Maier, Lisa, Strange, Charlie, Bowler, Russell P, Petrache, Irina, Serban, Karina A

“…Chronic obstructive pulmonary disease (COPD) is characterized by nonresolving inflammation fueled by breach in the endothelial barrier and leukocyte…”
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Lectin Complement Pathway in Emphysema by Serban, Karina A, Mikosz, Andrew, Strange, Charlie, Janciauskiene, Sabina M, Stolk, Jan, Jonigk, Danny, Sandhaus, Robert A, Petrache, Irina

“…The risk of lung disease in AATD is associated with decreased levels of circulating AAT, a proteinase inhibitor with high affinity for neutrophil-derived…”
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