Search Results - "Miko, Edit"
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miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5
Published in FEBS letters (20-04-2011)“…Despite intensive efforts to improve therapies, small cell lung cancer (SCLC) still has a dismal median survival of 18 months. Since miR-126 is under-expressed…”
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2
Effects of non-toxic zinc exposure on human epidermal keratinocytes
Published in Metallomics (01-03-2015)“…Zinc is an essential microelement; its importance to the skin is highlighted by the severe skin symptoms in hereditary or acquired zinc deficiency, by the…”
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3
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
Published in PloS one (29-06-2015)“…Major biological effects of UVB are attributed to cyclobutane pyrimidine dimers (CPDs), the most common photolesions formed on DNA. To investigate the…”
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4
The role of bile acids in carcinogenesis
Published in Cellular and molecular life sciences : CMLS (01-05-2022)“…Bile acids are soluble derivatives of cholesterol produced in the liver that subsequently undergo bacterial transformation yielding a diverse array of…”
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5
The role of the microbiome in ovarian cancer: mechanistic insights into oncobiosis and to bacterial metabolite signaling
Published in Molecular medicine (Cambridge, Mass.) (01-04-2021)“…Ovarian cancer is characterized by dysbiosis, referred to as oncobiosis in neoplastic diseases. In ovarian cancer, oncobiosis was identified in numerous…”
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6
The Trinity with Saints formerly Attributed to Jacopo Palma the Younger
Published in CeROArt (01-06-2017)“…In the 2015/16 academic year the conservation of a 16th century canvas painting formerly attributed to Jacopo Palma took place at the Conservation Department…”
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7
Cadaverine, a metabolite of the microbiome, reduces breast cancer aggressiveness through trace amino acid receptors
Published in Scientific reports (04-02-2019)“…Recent studies showed that changes to the gut microbiome alters the microbiome-derived metabolome, potentially promoting carcinogenesis in organs that are…”
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8
Metabolic roles of poly(ADP-ribose) polymerases
Published in Seminars in cell & developmental biology (01-03-2017)“…•PARP enzymes regulate metabolic transcription factors and energy sensor systems.•PARP-1 and PARP-2 regulate mitochondrial oxidation.•PARPs are involved in…”
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The involvement of oncobiosis and bacterial metabolite signaling in metastasis formation in breast cancer
Published in Cancer and metastasis reviews (01-12-2021)“…Breast cancer, the most frequent cancer in women, is characterized by pathological changes to the microbiome of breast tissue, the tumor, the gut, and the…”
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10
Cytostatic Bacterial Metabolites Interfere with 5-Fluorouracil, Doxorubicin and Paclitaxel Efficiency in 4T1 Breast Cancer Cells
Published in Molecules (Basel, Switzerland) (01-07-2024)“…The microbiome is capable of modulating the bioavailability of chemotherapy drugs, mainly due to metabolizing these agents. Multiple cytostatic bacterial…”
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11
Indolepropionic Acid, a Metabolite of the Microbiome, Has Cytostatic Properties in Breast Cancer by Activating AHR and PXR Receptors and Inducing Oxidative Stress
Published in Cancers (25-08-2020)“…Oncobiotic transformation of the gut microbiome may contribute to the risk of breast cancer. Recent studies have provided evidence that the microbiome secretes…”
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12
The Microbiome as a Component of the Tumor Microenvironment
Published in Advances in experimental medicine and biology (01-01-2020)“…Microbes, which live in the human body, affect a large set of pathophysiological processes. Changes in the composition and proportion of the microbiome are…”
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13
Lithocholic acid, a bacterial metabolite reduces breast cancer cell proliferation and aggressiveness
Published in Biochimica et biophysica acta. Bioenergetics (01-09-2018)“…Our study aimed at finding a mechanistic relationship between the gut microbiome and breast cancer. Breast cancer cells are not in direct contact with these…”
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14
Identification of Bacterial Metabolites Modulating Breast Cancer Cell Proliferation and Epithelial-Mesenchymal Transition
Published in Molecules (Basel, Switzerland) (01-08-2023)“…Breast cancer patients are characterized by the oncobiotic transformation of multiple microbiome communities, including the gut microbiome. Oncobiotic…”
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15
Microbiome-Microbial Metabolome-Cancer Cell Interactions in Breast Cancer-Familiar, but Unexplored
Published in Cells (Basel, Switzerland) (29-03-2019)“…Breast cancer is a leading cause of death among women worldwide. Dysbiosis, an aberrant composition of the microbiome, characterizes breast cancer. In this…”
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16
Oncobiosis and Microbial Metabolite Signaling in Pancreatic Adenocarcinoma
Published in Cancers (25-04-2020)“…Pancreatic adenocarcinoma is one of the most lethal cancers in both men and women, with a median five-year survival of around 5%. Therefore, pancreatic…”
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17
Profitability Optimization of Dairy Farms: The Effect of Pregnancy Rate and Culling Decision
Published in Animals (Basel) (20-12-2023)“…One of the most important decisions in dairy cattle production today is the correct choice of culling time for cows. In the culling decision process, the…”
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18
Evaluation of finger imprint persistence as a practical method for measuring the severity of mammary oedema in dairy cows
Published in Journal of Central European Agriculture (01-01-2024)“…The study aims to assess the severity of udder oedema around the calving using a traditional scoring (0-3 point scale) and the firstly applied fingerprint test…”
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Lithocholic Acid, a Metabolite of the Microbiome, Increases Oxidative Stress in Breast Cancer
Published in Cancers (27-08-2019)“…In breast cancer patients, the diversity of the microbiome decreases, coinciding with decreased production of cytostatic bacterial metabolites like lithocholic…”
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20
The pro- and antineoplastic effects of deoxycholic acid in pancreatic adenocarcinoma cell models
Published in Molecular biology reports (01-06-2023)“…Background Commensal bacteria secrete metabolites that reach distant cancer cells through the circulation and influence cancer behavior. Deoxycholic acid…”
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