Search Results - "Mikkola, Tomi S"
-
1
Use of postmenopausal hormone therapy and risk of Alzheimer's disease in Finland: nationwide case-control study
Published in BMJ (Online) (06-03-2019)“…To compare the use of hormone therapy between Finnish postmenopausal women with and without a diagnosis for Alzheimer's disease. Nationwide case-control study…”
Get full text
Journal Article -
2
Sex differences in age-related cardiovascular mortality
Published in PloS one (20-05-2013)“…Sex-related physiological differences result in different expressions of diseases for men and women. Data are contradicting regarding the increase in the…”
Get full text
Journal Article -
3
Estrogen Metabolism in Abdominal Subcutaneous and Visceral Adipose Tissue in Postmenopausal Women
Published in The journal of clinical endocrinology and metabolism (01-12-2017)“…Abstract Context In postmenopausal women, adipose tissue (AT) levels of estrogens exceed circulating concentrations. Although increased visceral AT after…”
Get full text
Journal Article -
4
Serum erythropoietin level is increased during stimulation for IVF but not in OHSS
Published in Reproductive biology and endocrinology (20-01-2024)“…Erythropoietin (Epo) is a potent vascular growth factor that induces angiogenesis and antiapoptotic signalling. We investigated whether the development of…”
Get full text
Journal Article -
5
Sex Steroid Hormone Analysis in Human Tear Fluid Using a Liquid Chromatography-Mass Spectrometry Method
Published in International journal of molecular sciences (28-11-2022)“…The marked sexual dimorphism prevalent in inflammatory/autoimmune diseases is mostly due to sex hormone actions. One common eye disease that disproportionately…”
Get full text
Journal Article -
6
Human adipocyte differentiation and composition of disease-relevant lipids are regulated by miR-221-3p
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-01-2021)“…MicroRNA-221-3p (miR-221-3p) is associated with both metabolic diseases and cancers. However, its role in terminal adipocyte differentiation and lipid…”
Get full text
Journal Article -
7
Direct Ink Writing of Biocompatible Nanocellulose and Chitosan Hydrogels for Implant Mesh Matrices
Published in ACS polymers Au (13-04-2022)“…Direct ink writing via single or multihead extrusion is used to synthesize layer-by-layer (LbL) meshes comprising renewable polysaccharides. The best…”
Get full text
Journal Article -
8
Pelvic organ prolapse repair using the Uphold™ Vaginal Support System: a 1-year multicenter study
Published in International Urogynecology Journal (01-09-2016)“…Introduction and hypothesis The objective was to assess safety and clinical outcomes in women operated on using the Uphold™ Lite Vaginal Support System…”
Get full text
Journal Article -
9
Coronary Heart Disease Mortality and Hormone Therapy Before and After the Women's Health Initiative
Published in Obstetrics and gynecology (New York. 1953) (01-11-2014)“…To assess whether coronary heart disease mortality in Finnish hormone therapy (HT) users differed before and after 2002 when the Women's Health Initiative…”
Get full text
Journal Article -
10
Postmenopausal hormone therapy and coronary heart disease in early postmenopausal women
Published in Annals of medicine (Helsinki) (01-02-2014)“…In women, cardiovascular disease (CVD) accounts for about half of all deaths in Western countries. It is generally accepted that endogenous estrogen protects…”
Get more information
Journal Article -
11
Maternal childbirth experience and induction of labour in each mode of delivery: a retrospective seven-year cohort study of 95,051 parturients in Finland
Published in BMC pregnancy and childbirth (23-06-2022)“…Abstract Background Childbirth experience has been shown to depend on the mode of delivery. However, it is unclear how labour induction influences the…”
Get full text
Journal Article -
12
Association of serum cortisol and cortisone levels and risk of recurrence after endocrine treatment in breast cancer
Published in Clinical and experimental medicine (2023)“…Metabolic reprogramming in breast cancer involves changes in steroid hormone synthesis and metabolism. Alterations in estrogen levels in both breast tissue and…”
Get full text
Journal Article -
13
Evaluation of a Web Course on the Basics of Gynecological Laparoscopy in Resident Training
Published in Journal of surgical education (01-07-2017)“…Objectives Reduction in the number of gynecological operations has made resident training more difficult in gynecological surgery. We used electronic…”
Get full text
Journal Article -
14
Postmenopausal hormone therapy increases retinal blood flow and protects the retinal nerve fiber layer
Published in Investigative ophthalmology & visual science (01-05-2010)“…To investigate whether postmenopausal hormone therapy (HT) increases retinal and ONH blood flow (BF) and protects ONH topography and the function of retinal…”
Get full text
Journal Article -
15
Quantitative determination of estrone by liquid chromatography–tandem mass spectrometry in subcutaneous adipose tissue from the breast in postmenopausal women
Published in The Journal of steroid biochemistry and molecular biology (01-01-2016)“…•We developed a reproducible LC–MS/MS method to quantify estrone in adipose tissue.•The method was applied to adipose tissue from the breast in postmenopausal…”
Get full text
Journal Article -
16
Postmenopausal hot flushes and bone mineral density: a longitudinal study
Published in Acta obstetricia et gynecologica Scandinavica (01-02-2015)“…To study the possible association between menopausal hot flushes and bone mineral density. Observational study. University clinic. Healthy women (n = 143) with…”
Get more information
Journal Article -
17
Effect of aerobic training on menopausal symptoms—a randomized controlled trial
Published in Menopause (New York, N.Y.) (01-06-2012)“…OBJECTIVEThe aim of this study was to assess whether aerobic training affects menopausal symptoms in recently postmenopausal sedentary women…”
Get full text
Journal Article -
18
Increased Cardiovascular Mortality Risk in Women Discontinuing Postmenopausal Hormone Therapy
Published in The journal of clinical endocrinology and metabolism (01-12-2015)“…Context: Current guidelines recommend annual discontinuation of postmenopausal hormone therapy (HT) to evaluate whether a woman could manage without the…”
Get full text
Journal Article -
19
Tension-Free Vaginal Tape Surgery versus Polyacrylamide Hydrogel Injection for Primary Stress Urinary Incontinence: A Randomized Clinical Trial
Published in The Journal of urology (01-02-2020)“…We evaluated whether polyacrylamide hydrogel is noninferior to tension-free vaginal tape to treat women with primary stress urinary incontinence. In this…”
Get full text
Journal Article -
20
Estradiol-based postmenopausal hormone therapy and risk of cardiovascular and all-cause mortality
Published in Menopause (New York, N.Y.) (01-09-2015)“…OBJECTIVE:Data on the health benefits and risks of postmenopausal hormone therapy (HT) are derived mainly from the use of conjugated equine estrogens…”
Get full text
Journal Article