Search Results - "Mikkola, Jouni"
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ASSESSMENT OF CATECHOL INDUCTION AND GLUCURONIDATION IN RAT LIVER MICROSOMES
Published in Drug metabolism and disposition (01-12-2004)“…Catechols are substances with a 1,2-dihydroxybenzene group from natural or synthetic origin. The aim of this study was to determine whether catechols…”
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Glucuronidation of 1-Hydroxypyrene by Human Liver Microsomes and Human UDP-Glucuronosyltransferases UGT1A6, UGT1A7, and UGT1A9: Development of a High-Sensitivity Glucuronidation Assay for Human Tissue
Published in Drug metabolism and disposition (01-08-2001)“…Human UDP-glucuronosyltransferases (UGT, EC 2.4.1.17 ) involved in the biotransformation of pyrene were investigated by a sensitive fluorometric…”
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Firefighters’ multiple exposure assessments in practice
Published in Toxicology letters (13-08-2012)“…► Multiple exposures via multi-route exposure should be taken into account. ► PAHs in the air should be linked to the excretion level of 1-hydroxypyrene. ► The…”
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Journal Article Conference Proceeding -
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Fire fighting trainers’ exposure to carcinogenic agents in smoke diving simulators
Published in Toxicology letters (15-01-2010)“…It is well known that fire fighters are potentially exposed to various carcinogenic agents at a fire scene. An almost unheeded issue, however, is fire…”
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Journal Article Conference Proceeding -
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Oxidative stress induced by fumonisin B1 in continuous human and rodent neural cell cultures
Published in Free radical research (01-09-2004)“…Fumonisin B1 (FB1) is a mycotoxin produced by Fusarium verticillioides, which is a common infectant of corn and other cereal grains. Of concern to human health…”
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Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver
Published in Archives of toxicology (01-03-2007)“…In order to survey changes and activities in the polycyclic aromatic hydrocarbon (PAH)-metabolizing enzymes implicated in lung cancer susceptibility studies,…”
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Fumonisin B1-induced toxicity and oxidative damage in U-118MG glioblastoma cells
Published in Toxicology (Amsterdam) (01-10-2004)“…The mycotoxin fumonisin B1 (FB1) is produced by Fusarium verticillioides, which commonly infects corn and other agricultural products. Fusarium species are…”
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Assessment of soil remediation workers’ exposure to polycyclic aromatic hydrocarbons (PAH): Biomonitoring of naphthols, phenanthrols, and 1-hydroxypyrene in urine
Published in Toxicology letters (10-04-2006)“…Urinalysis of multiple polycyclic aromatic hydrocarbons (PAH) biomarkers has been applied to assess the exposure of soil remediation workers on a former…”
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Journal Article Conference Proceeding -
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Fumonisin B 1-induced toxicity and oxidative damage in U-118MG glioblastoma cells
Published in Toxicology (Amsterdam) (01-10-2004)“…The mycotoxin fumonisin B 1 (FB 1) is produced by Fusarium verticillioides, which commonly infects corn and other agricultural products. Fusarium species are…”
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Simultaneous analysis of naphthols, phenanthrols, and 1-hydroxypyrene in urine as biomarkers of polycyclic aromatic hydrocarbon exposure: intraindividual variance in the urinary metabolite excretion profiles caused by intervention with β-naphthoflavone induction in the rat
Published in Archives of toxicology (01-04-2003)“…Two fluorimetric HPLC methods are described for the quantification of naphthols, phenanthrols and 1-hydroxypyrene (1-OHP) in urine specimens obtained from male…”
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Interactive effects of methyl tertiary-butyl ether (MTBE) and tertiary-amyl methyl ether (TAME), ethanol and some drugs: Triglyceridemia, liver toxicity and induction of CYP (2E1, 2B1) and phase II enzymes in female Wistar rats
Published in Environmental toxicology and pharmacology (01-01-2007)“…Abstract The abilities of the gasoline additives methyl tert -butyl ether (MTBE) and tert -amyl methyl ether (TAME) to cause liver damage following oral…”
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Biological monitoring of benzene exposure during maintenance work in crude oil cargo tanks
Published in Chemico-biological interactions (01-12-2006)“…We investigated the association between the individual concentrations of benzene in the breathing zone and the concentrations of benzene in the blood and urine…”
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1-Naphthol, indicator of dermal exposure to kerosene in fuel cell maintenance work of military aircraft
Published in Toxicology letters (05-10-2008)Get full text
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Simultaneous analysis of naphthols, phenanthrols, and 1-hydroxypyrene in urine as biomarkers of polycyclic aromatic hydrocarbon exposure: intraindividual variance in the urinary metabolite excretion profiles caused by intervention with [beta]-naphthoflavone induction in the rat
Published in Archives of toxicology (01-04-2003)“…Two fluorimetric HPLC methods are described for the quantification of naphthols, phenanthrols and 1-hydroxypyrene (1-OHP) in urine specimens obtained from male…”
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Journal Article