Search Results - "Mikkelsson, J"
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Radiographic Assessment of Dental Health in Middle-aged Men Following Sudden Cardiac Death
Published in Journal of dental research (01-01-2006)“…Poor oral health has been suggested to be a risk factor for myocardial infarction. To study if dental pathology might predispose to pre-hospital sudden cardiac…”
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Fibrinogen gene promoter -455 A allele as a risk factor for lacunar stroke
Published in Stroke (1970) (01-04-2003)“…Elevated fibrinogen levels are suggested to increase the risk of myocardial infarction and stroke. Carriers of the A allele of the fibrinogen -455G/A…”
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Polymorphisms within the tumor necrosis factor locus and prevalence of coronary artery disease in middle-aged men
Published in Atherosclerosis (15-02-2001)“…Tumor necrosis factor (TNF) is an important cytokine in the inflammation process of atherosclerosis and is also involved in lipid metabolism. Two biallelic…”
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The hepatic lipase gene C-480T polymorphism in the development of early coronary atherosclerosis: the Helsinki Sudden Death Study
Published in European journal of clinical investigation (01-06-2007)“…Background The T allele of the hepatic lipase (HL) C‐480T polymorphism was previously found to be associated with lower post‐heparin plasma HL activity,…”
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Coronary artery calcification is related to functional polymorphism of matrix metalloproteinase 3: the Helsinki Sudden Death Study
Published in Atherosclerosis (01-10-2002)“…Matrix metalloproteinase 3 ( MMP3) is expressed in human coronary atherosclerotic lesions and is known to be involved in degradation of the plaque and to be…”
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Toll-like receptor 4 polymorphism is associated with coronary stenosis but not with the occurrence of acute or old myocardial infarctions
Published in Scandinavian journal of clinical and laboratory investigation (2006)“…Objective. Atherosclerosis is considered to be a chronic inflammatory disease. Toll-like receptor 4 (TLR-4), a key mediator in activating inflammatory cascade,…”
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A Functional variant of the iNOS gene flanking region is associated with LAD coronary artery disease: an autopsy study
Published in European journal of clinical investigation (01-12-2003)“…Background Recent studies using reporter gene constructs have indicated significant differences in the promoter activity of inducible nitric oxide synthase…”
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The GPIIIa Pl A polymorphism in the progression of abdominal aortic atherosclerosis
Published in Atherosclerosis (01-11-1999)“…Glycoprotein IIIa is expressed in platelets as part of the fibrinogen receptor and also in vascular endothelium where it mediates smooth muscle cell…”
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The GPIIIa PlA polymorphism in the progression of abdominal aortic atherosclerosis
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Outcome of ST-elevation myocardial infarction versus non-ST-elevation acute coronary syndrome treated with titanium-nitride-oxide-coated versus everolimus-eluting stents: insights from the BASE-ACS trial
Published in Minerva cardioangiologica (01-04-2013)“…The BASE-ACS trial demonstrated an outcome of titanium-nitride-oxide-coated bioactive stents (BAS) that was statistically non-inferior to that of…”
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Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients
Published in Thrombosis and haemostasis (01-02-2006)“…The antiplatelet effect of aspirin varies individually. This study evaluated whether the antiplatelet effect of aspirin associates with polymorphisms in the…”
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Platelet membrane collagen receptor glycoprotein VI polymorphism is associated with coronary thrombosis and fatal myocardial infarction in middle-aged men
Published in Atherosclerosis (01-09-2004)“…Glycoprotein VI is a platelet collagen receptor binding to subendothelial collagen after a rupture of an atherosclerotic plaque. The GPVI gene is polymorphic…”
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Transthoracic echocardiography for non-invasive assessment of coronary vasodilator function after DES implantation
Published in European heart journal cardiovascular imaging (01-09-2014)“…Coronary vasodilator dysfunction has been reported after drug-eluting stent (DES) implantation. Recent ESC guidelines suggest that transthoracic…”
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Platelet glycoprotein Ibα HPA-2 Met/VNTR B haplotype as a genetic predictor of myocardial infarction and Sudden cardiac Death
Published in Circulation (New York, N.Y.) (21-08-2001)“…Background — Sudden cardiac death (SCD) is one of the leading manifestations of coronary heart disease in early middle age. Platelet glycoprotein (GP) Ib-IX-V…”
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Coronary Artery Complicated Lesion Area Is Related to Functional Polymorphism of Matrix Metalloproteinase 9 Gene: An Autopsy Study
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2001)“…Matrix metalloproteinase 9 (MMP9) is expressed in human atherosclerotic plaques, and the protein is localized in human coronary atherosclerotic lesions. The…”
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Glycoprotein IIIa Pl(A1/A2) polymorphism and sudden cardiac death
Published in Journal of the American College of Cardiology (01-10-2000)“…We studied the association of the Pl(A1/A2) polymorphism with coronary thrombosis, myocardial infarction (MI) and sudden cardiac death (SCD) in autopsied…”
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ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study
Published in Annals of medicine (Helsinki) (2009)“…Previously, we scanned all 23,000 human genes for differential expression between normal and atherosclerotic tissues and found the involvement of ADAM8. We…”
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Matrix metalloproteinase 3 and 9 gene promoter polymorphisms: joint action of two loci as a risk factor for coronary artery complicated plaques
Published in Atherosclerosis (01-05-2005)“…Matrix metalloproteinases 3 and 9 (MMP3 and MMP9) are present in atherosclerotic plaques and co-operate in the degradation of the fibrous cap of the atheroma,…”
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Glycoprotein IIIa Pl(A) polymorphism associates with progression of coronary artery disease and with myocardial infarction in an autopsy series of middle-aged men who died suddenly
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-1999)“…Glycoprotein IIIa (GPIIIa) has a key role in the aggregation of thrombocytes, and it also mediates intimal hyperplasia after endothelial injuries; the possible…”
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