Search Results - "Mikics, Eva"

Changes in neuroplasticity following early-life social adversities: the possible role of brain-derived neurotrophic factor by Miskolczi, Christina, Halász, József, Mikics, Éva

“…Social adversities experienced in childhood can have a profound impact on the developing brain, leading to the emergence of psychopathologies in adulthood…”
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Social Learning Requires Plasticity Enhanced by Fluoxetine Through Prefrontal Bdnf-TrkB Signaling to Limit Aggression Induced by Post-Weaning Social Isolation by Mikics, Éva, Guirado, Ramon, Umemori, Juzoh, Tóth, Máté, Biró, László, Miskolczi, Christina, Balázsfi, Diána, Zelena, Dóra, Castrén, Eero, Haller, József, Karpova, Nina N

“…Escalated or abnormal aggression induced by early adverse experiences is a growing issue of social concern and urges the development of effective treatment…”
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The effects of non-genomic glucocorticoid mechanisms on bodily functions and the central neural system. A critical evaluation of findings by Haller, József, Mikics, Éva, Makara, Gábor B

“…Abstract Mounting evidence suggests that—beyond the well-known genomic effects—glucocorticoids affect cell function via non-genomic mechanisms. Such mechanisms…”
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Rats exposed to traumatic stress bury unfamiliar objects — A novel measure of hyper-vigilance in PTSD models? by Mikics, Eva, Baranyi, Johanna, Haller, Jozsef

“…Abstract Electric shocks lead to lasting behavioral deficits in rodents, and as such are often used to model post-traumatic stress disorder (PTSD) in the…”
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The swimming plus-maze test: a novel high-throughput model for assessment of anxiety-related behaviour in larval and juvenile zebrafish (Danio rerio) by Varga, Zoltán K., Zsigmond, Áron, Pejtsik, Diána, Varga, Máté, Demeter, Kornél, Mikics, Éva, Haller, József, Aliczki, Manó

“…Larval zebrafish ( Danio rerio ) has the potential to supplement rodent models due to the availability of resource-efficient, high-throughput screening and…”
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Effects of resocialization on post-weaning social isolation-induced abnormal aggression and social deficits in rats by Tulogdi, Áron, Tóth, Máté, Barsvári, Beáta, Biró, László, Mikics, Éva, Haller, József

“…As previously shown, rats isolated from weaning develop abnormal social and aggressive behavior characterized by biting attacks targeting vulnerable body parts…”
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The role of GluN2B-containing NMDA receptors in short- and long-term fear recall by Mikics, Eva, Toth, Mate, Biro, Laszlo, Bruzsik, Biborka, Nagy, Boglarka, Haller, Jozsef

“…Abstract N -methyl- d -aspartate (NMDA) receptors are crucial synaptic elements in long-term memory formation, including the associative learning of fearful…”
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The neural background of hyper-emotional aggression induced by post-weaning social isolation by Toth, Mate, Tulogdi, Aron, Biro, Laszlo, Soros, Petra, Mikics, Eva, Haller, Jozsef

“…[Display omitted] ► Post-weaning isolation induces hyper-emotional, exaggerated, abnormal aggression. ► Brain (c-Fos) activation patterns were compared to…”
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Conserved serotonergic background of experience-dependent behavioral responsiveness in zebrafish ( Danio rerio ) by Varga, Zoltán K, Pejtsik, Diána, Biró, László, Zsigmond, Áron, Varga, Máté, Tóth, Blanka, Salamon, Vilmos, Annus, Tamás, Mikics, Éva, Aliczki, Manó

“…Forming effective responses to threatening stimuli requires the adequate and coordinated emergence of stress-related internal states. Such ability depends on…”
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Neurochemically distinct populations of the bed nucleus of stria terminalis modulate innate fear response to weak threat evoked by predator odor stimuli by Bruzsik, Biborka, Biro, Laszlo, Sarosdi, Klara Rebeka, Zelena, Dora, Sipos, Eszter, Szebik, Huba, Török, Bibiána, Mikics, Eva, Toth, Mate

“…Anxiety and trauma-related disorders are characterized by significant alterations in threat detection, resulting in inadequate fear responses evoked by weak…”
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Early Social Deprivation Induces Disturbed Social Communication and Violent Aggression in Adulthood by Tóth, Máté, Halász, József, Mikics, Éva, Barsy, Boglárka, Haller, József

“…Disturbed social relations during childhood (e.g., social neglect) often lead to aggression-related psychopathologies in adulthood. Social isolation also…”
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Post-weaning social isolation in male mice leads to abnormal aggression and disrupted network organization in the prefrontal cortex: Contribution of parvalbumin interneurons with or without perineuronal nets by Biro, Laszlo, Miskolczi, Christina, Szebik, Huba, Bruzsik, Biborka, Varga, Zoltan Kristof, Szente, Laszlo, Toth, Mate, Halasz, Jozsef, Mikics, Eva

“…Adverse social experiences during childhood increase the risk of developing aggression-related psychopathologies. The prefrontal cortex (PFC) is a key…”
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Endocannabinoid and neuroplasticity-related changes as susceptibility factors in a rat model of posttraumatic stress disorder by Szente, Laszlo, Balla, Gyula Y., Varga, Zoltan K., Toth, Blanka, Biro, Laszlo, Balogh, Zoltan, Hill, Matthew N., Toth, Mate, Mikics, Eva, Aliczki, Mano

“…Traumatic experiences result in the development of posttraumatic stress disorder (PTSD) in 10–25% of exposed individuals. While human clinical studies suggest…”
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Behavioral specificity of non-genomic glucocorticoid effects in rats: Effects on risk assessment in the elevated plus-maze and the open-field by Mikics, Éva, Barsy, Boglárka, Barsvári, Beáta, Haller, József

“…The rapid effects of glucocorticoids on various behaviors suggest that these hormones play a role in rapidly coping with challenging situations. The variety of…”
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Enduring abolishment of remote but not recent expression of conditioned fear by the blockade of calcium-permeable AMPA receptors before extinction training by Zelena, Dóra, Mikics, Éva, Balázsfi, Diána, Varga, János, Klausz, Barbara, Urbán, Eszter, Sipos, Eszter, Biró, László, Miskolczi, Christina, Kovács, Krisztina, Ferenczi, Szilamér, Haller, József

“…Rationale Calcium-permeable (GluA2 subunit-free) AMPA receptors (CP-AMPAR) play prominent roles in fear extinction; however, no blockers of these receptors…”
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The effect glucocorticoids on aggressiveness in established colonies of rats by Mikics, Éva, Barsy, Boglárka, Haller, József

“…Summary It was repeatedly shown that glucocorticoids increase aggressiveness when subjects are socially challenged. However, the interaction between challenge…”
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The long-term impact of footshock stress on addiction-related behaviors in rats by Barsy, Boglárka, Mikics, Éva, Barsvári, Beáta, Haller, József

“…We investigated the impact of electric shocks – frequently used to model post-traumatic stress disorder in rodents – on behaviors relevant to drug abuse in…”
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Do stress hormones connect environmental effects with behavior in the forced swim test? by Pintér, Ottó, Domokos, Ágnes, Mergl, Zsuzsa, Mikics, Éva, Zelena, Dóra

“…Forced swim test (FST) is a widely used test for antidepressant development. Depression is a stress related disease, as hormones of the stress-axis can modify…”
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Mechanisms differentiating normal from abnormal aggression: Glucocorticoids and serotonin by Haller, Jozsef, Mikics, Éva, Halász, József, Tóth, Máthé

“…Psychopathology-associated human aggression types are induced by a variety of conditions, are behaviorally variable, and show a differential pharmacological…”
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Temporal changes in c-Fos activation patterns induced by conditioned fear by Tulogdi, Áron, Sörös, Petra, Tóth, Máté, Nagy, Rita, Biró, László, Aliczki, Manó, Klausz, Barbara, Mikics, Éva, Haller, József

“…Graphical abstract Highlights ► Conditioned fear responses shown 1 and 28 days after footshocks are similar. ► Brain (c-Fos) activation patterns are markedly…”
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