Search Results - "Miki, Toyokazu"

Development of a New Triage Method to Prioritize Patients Arriving at the Emergency Room by Natsukawa, Tomoaki, Deguchi, Ryo, Akita, Naoki, Uemori, Sadayori, Miki, Toyokazu, Kato, Noboru

“…Introduction:By prioritizing emergency patients, triage facilitates the timely provision of care to the largest possible number of patients arriving at an…”
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A report of two bronchioloalveolar carcinoma cases which were rapidly improved by treatment with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa1) by YANO, Seiji, KANEMATSU, Takanori, MIKI, Toyokazu, AONO, Yoshinori, AZUMA, Masahiko, YAMAMOTO, Akihiko, UEHARA, Hisanori, SONE, Saburo

“…Bronchioloalveolar carcinoma (BAC), a form of pulmonary adenocarcinoma, presents unique clinical features, such as endobronchial spread and bronchorrhea in…”
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Multifunctional interleukin‐1β promotes metastasis of human lung cancer cells in SCID mice via enhanced expression of adhesion‐, invasion‐ and angiogenesis‐related molecules by Yano, Seiji, Nokihara, Hiroshi, Yamamoto, Akihiko, Goto, Hisatsugu, Ogawa, Hirohisa, Kanematsu, Takanori, Miki, Toyokazu, Uehara, Hisanori, Saijo, Yasuo, Nukiwa, Toshihiro, Sone, Saburo

“…We examined whether interleukin‐1 (IL‐1), a multifunctional proinflammatory cytokine, progresses or regresses metastasis of lung cancer. Exogenous IL‐lβ…”
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Soluble Fas in malignant pleural effusion and its expression in lung cancer cells by Mitani, Kayo, Nishioka, Yasuhiko, Yamabe, Kazue, Ogawa, Hirohisa, Miki, Toyokazu, Yanagawa, Hiroaki, Sone, Saburo

“…Soluble Fas (sFas) has the ability to block Fas‐mediated apoptosis, suggesting that sFas at tumor sites might inhibit tumor cell‐killing by immune effector…”
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Combined Therapy with a New Bisphosphonate, Minodronate (YM529), and Chemotherapy for Multiple Organ Metastases of Small Cell Lung Cancer Cells in Severe Combined Immunodeficient Mice by YANO, Seiji, HELONG ZHANG, HANIBUCHI, Masaki, MIKI, Toyokazu, GOTO, Hisatsugu, UEHARA, Hisanori, SONE, Saburo

“…Purpose: Lung cancer in the advanced stage frequently metastasizes to multiple organs, including the liver, lungs, lymph nodes, and bone. Bisphosphonates have…”
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The use of continuous hemodiafiltration in a patient with diabetic ketoacidosis by Kawata, Hitomi, Inui, Daisuke, Ohto, Jun, Miki, Toyokazu, Suzue, Atsuhiko, Fukuta, Yasushi, Nishimura, Masaji

“…A variety of fatal complications are associated with diabetes mellitus. Among these, diabetic ketoacidosis (DKA) figures largely in fatalities in young…”
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Transduction ofKAI1/CD82 cDNA promotes hematogenous spread of human lung-cancer cells in natural killer cell-depleted SCID mice by Shinohara, Tsutomu, Nishimura, Naoki, Hanibuchi, Masaki, Nokihara, Hiroshi, Miki, Toyokazu, Hamada, Hirofumi, Sone, Saburo

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Six cases of rhabdomyolysis induced by dehydration by Inui, Daisuke, Fukuta, Yasushi, Oto, Jun, Miki, Toyokazu, Suzue, Atsuhiko, Kawahito, Shinji, Oshita, Shuzo, Nishimura, Masaji

“…Rhabdomyolysis results from a variety of causes. We experienced 6 cases of rhabdomyolysis induced by dehydration in psychoneurosis patients or seniors. We…”
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Heterogeneity of multiorgan metastases of human lung cancer cells genetically engineered to produce cytokines and reversal using chimeric monoclonal antibodies in natural killer cell-depleted severe combined immunodeficient mice by SONE, S, YANO, S, HANIBUCHI, M, NOKIHARA, H, NISHIMURA, N, MIKI, T, NISHIOKA, Y, SHINOHARA, T

“…Lung cancer is a major cause of cancer deaths, most of which can be attributed to distant multiorgan metastases. To examine the cellular and molecular…”
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Parathyroid hormone‐related protein (PTHrP) is responsible for production of bone metastasis, but not visceral metastasis, by human small cell lung cancer SBC‐5 cells in natural killer cell‐depleted SCID mice by Miki, Toyokazu, Yano, Seiji, Hanibuchi, Masaki, Kanematsu, Takanori, Muguruma, Hiroaki, Sone, Saburo

“…We previously established an osteolytic bone metastasis model with multiorgan dissemination in natural killer (NK) cell‐depleted severe combined…”
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STEC:O111‐HUS complicated by acute encephalopathy in a young girl was successfully treated with a set of hemodiafiltration, steroid pulse, and soluble thrombomodulin under plasma exchange by Yada, Noritaka, Fujioka, Masayuki, Bennett, Charles L., Inoki, Kazuya, Miki, Toyokazu, Watanabe, Akihiko, Yoshida, Toshiko, Hayakawa, Masaki, Matsumoto, Masanori, Fujimura, Yoshihiro

“…Key Clinical Message We report a 14‐year‐old girl, who developed shigatoxin‐producing E. coli (STEC)‐HUS complicated by encephalopathy. She was successfully…”
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Organ heterogeneity of host-derived matrix metalloproteinase expression and its involvement in multiple-organ metastasis by lung cancer cell lines by SHIRAGA, Minoru, YANO, Seiji, YAMAMOTO, Akihiko, OGAWA, Hirohisa, GOTO, Hisatsugu, MIKI, Toyokazu, MIKI, Keisuke, HELONG ZHANG, SONE, Saburo

“…Cancer metastasis is tightly regulated by the interaction of tumor cells and host organ microenvironments. Matrix metalloproteinases (MMPs), produced by both…”
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A third‐generation matrix metalloproteinase (MMP) inhibitor (ONO‐4817) combined with docetaxel suppresses progression of lung micrometastasis of MMP‐expressing tumor cells in nude mice by Yamamoto, Akihiko, Yano, Seiji, Shiraga, Minoru, Ogawa, Hirohisa, Goto, Hisatsugu, Miki, Toyokazu, Zhang, Helong, Sone, Saburo

“…The lung is the common target organ of hematogenous metastasis that restricts the prognosis of cancer patients. MMPs play a pivotal role in metastasis by…”
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Nuclear factor-κB-dependent expression of metastasis suppressor KAI1/CD82 gene in lung cancer cell lines expressing mutant p53 by SHINOHARA, Tsutomu, MIKI, Toyokazu, NISHIMURA, Naoki, NOKIHARA, Hiroshi, HAMADA, Hirofumi, MUKAIDA, Naofumi, SONE, Saburo

“…KAI1/CD82 has been shown to be a metastasis suppressor for several human cancers, and a recent study revealed that wild-type tumor suppressor p53 can directly…”
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A novel bisphosphonate minodronate (YM529) specifically inhibits osteolytic bone metastasis produced by human small-cell lung cancer cells in NK-cell depleted SCID mice by Zhang, Helong, Yano, Seiji, Miki, Toyokazu, Goto, Hisatsugu, Kanematsu, Takanori, Muguruma, Hiroaki, Uehara, Hisanori, Sone, Saburo

“…In the present study, we examined the effects of a newly developed bisphosphonate, minodronate (YM529), on osteolytic bone metastasis caused by lung cancer…”
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Bone metastasis model with multiorgan dissemination of human small-cell lung cancer (SBC-5) cells in natural killer cell-depleted SCID mice by Miki, T, Yano, S, Hanibuchi, M, Sone, S

“…Lung cancer is commonly associated with multiorgan metastasis, and bone is a frequent metastatic site for lung cancer. Nevertheless, no bone metastasis model…”
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Distribution of immunoreactivities for adenohypophysial hormones in the pituitary gland of the polypteriform fish, Polypterus endlicheri by Miki, Makoto, Shimotani, Toyokazu, Nozaki, Masumi

“…Polypteriform fish constitutes the most primitive living descendent of the ancient bony fish. In polypteriform fish, only proopiomelanocortin (POMC) has been…”
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A report of two bronchioloalveolar carcinoma cases which were rapidly improved by treatment with the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (“Iressa”1 by Yano, Seiji, Kanematsu, Takanori, Miki, Toyokazu, Aono, Yoshinori, Azuma, Masahiko, Yamamoto, Akihiko, Uehara, Hisanori, Sone, Saburo

“…Bronchioloalveolar carcinoma (BAC), a form of pulmonary adeno‐carcinoma, presents unique clinical features, such as endobron‐chial spread and bronchorrhea in…”
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Transduction of KAI1/CD82 cDNA promotes hematogenous spread of human lung‐cancer cells in natural killer cell–depleted SCID mice by Shinohara, Tsutomu, Nishimura, Naoki, Hanibuchi, Masaki, Nokihara, Hiroshi, Miki, Toyokazu, Hamada, Hirofumi, Sone, Saburo

“…KAI1, which is identical to CD82, was initially identified as a metastasis‐suppressor gene for human prostate cancer, and its expression is reported to be a…”
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Transduction of KA11/CD82 cDNA promotes hematogenous spread of human lung-cancer cells in natural killer cell-depleted SCID mice by SHINOHARA, Tsutomu, NISHIMURA, Naoki, HANIBUCHI, Masaki, NOKIHARA, Hiroshi, MIKI, Toyokazu, HAMADA, Hirofumi, SONE, Saburo

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