Search Results - "Miki, S."
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1
Chip-based quantum key distribution
Published in Nature communications (09-02-2017)“…Improvement in secure transmission of information is an urgent need for governments, corporations and individuals. Quantum key distribution (QKD) promises…”
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2
A biomimetic approach for enhancing the in vivo half-life of peptides
Published in Nature chemical biology (01-10-2015)“…Linking a peptide with a small-molecule ligand for the serum protein transthyretin ensures half-life extension without diminishing potency through protection…”
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3
Single-photon emission at 1.5 μm from an InAs/InP quantum dot with highly suppressed multi-photon emission probabilities
Published in Applied physics letters (26-09-2016)“…We have demonstrated highly pure single-photon emissions from an InAs/InP quantum dot at the wavelength of 1.5 μm. By applying quasi-resonant excitation, one…”
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4
Nuclear RNA Regulation by XRN2 and XTBD Family Proteins
Published in Cell Structure and Function (2021)“…XRN2 is a 5'-to-3' exoribonuclease that is predominantly localized in the nucleus. By degrading or trimming various classes of RNA, XRN2 contributes to…”
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5
Two distinct transcription termination modes dictated by promoters
Published in Genes & development (15-09-2017)“…Transcription termination determines the ends of transcriptional units and thereby ensures the integrity of the transcriptome and faithful gene regulation…”
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6
The multifunctional RNase XRN2
Published in Biochemical Society transactions (01-08-2013)“…Different classes of RNA function in various cellular processes, and their biogenesis and turnover involve diverse RNases for processing and degradation. XRN2…”
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7
AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin
Published in Proceedings of the National Academy of Sciences - PNAS (11-06-2013)“…The misassembly of soluble proteins into toxic aggregates, including amyloid fibrils, underlies a large number of human degenerative diseases. Cardiac…”
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8
Multi-walled carbon nanotube-reinforced magnesium alloy composites
Published in Scripta materialia (01-02-2008)“…This study demonstrates the ability to fabricate lightweight, ductile but mechanically strong magnesium alloy (AZ91D) composites by introducing a small number…”
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9
Enhancing the Pharmacokinetic Profile of Interleukin 2 through Site-Specific Conjugation to a Selective Small-Molecule Transthyretin Ligand
Published in Journal of medicinal chemistry (14-10-2021)“…Protein drugs hold great promise as therapeutics for a wide range of diseases. Unfortunately, one of the greatest challenges to be addressed during clinical…”
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10
Field test of quantum key distribution in the Tokyo QKD Network
Published in Optics express (23-05-2011)“…A secure communication network with quantum key distribution in a metropolitan area is reported. Six different QKD systems are integrated into a mesh-type…”
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11
A germline-targeted genetic screen for xrn-2 suppressors identifies a novel gene C34C12.2 in Caenorhabditis elegans
Published in Genetics and molecular biology (01-01-2023)“…XRN2 is an evolutionarily conserved 5'-to-3' exoribonuclease, which degrades or trims various types of RNA in the nucleus. Although XRN-2 is essential for…”
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12
Peripherally restricted transthyretin-based delivery system for probes and therapeutics avoiding opioid-related side effects
Published in Nature communications (23-06-2022)“…Several investigations into the sites of action of opioid analgesics have utilized peripherally acting mu-opioid receptor antagonists (PAMORAs), which have…”
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13
Computer-Assisted Detection of Cerebral Aneurysms in MR Angiography in a Routine Image-Reading Environment: Effects on Diagnosis by Radiologists
Published in American journal of neuroradiology : AJNR (01-06-2016)“…Experiences with computer-assisted detection of cerebral aneurysms in diagnosis by radiologists in real-life clinical environments have not been reported. The…”
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14
Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast
Published in Cell reports (Cambridge) (16-10-2018)“…CDH1 and PIK3CA are the two most frequently mutated genes in invasive lobular carcinoma (ILC) of the breast. Transcription profiling has identified molecular…”
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15
XRN2 Autoregulation and Control of Polycistronic Gene Expresssion in Caenorhabditis elegans
Published in PLoS genetics (15-09-2016)“…XRN2 is a conserved 5'→3' exoribonuclease that complexes with proteins that contain XRN2-binding domains (XTBDs). In Caenorhabditis elegans (C. elegans), the…”
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16
Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells
Published in Proceedings of the National Academy of Sciences - PNAS (24-01-2023)“…Mutations in , and are recurrently observed in myeloid neoplasms. and encode isocitrate dehydrogenase isoforms, which normally catalyze the conversion of…”
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17
Origin of intrinsic dark count in superconducting nanowire single-photon detectors
Published in Applied physics letters (17-10-2011)“…The origin of the decoherence in superconducting nanowire single-photon detectors, the so-called dark count, was investigated. We measured the direct-current…”
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18
PAXT-1 Promotes XRN2 Activity by Stabilizing It through a Conserved Domain
Published in Molecular cell (23-01-2014)“…XRN2 is an essential eukaryotic exoribonuclease that processes and degrades various substrates. Here we identify the previously uncharacterized protein…”
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19
Characterization and evolutionary analysis of tributyltin‐binding protein and pufferfish saxitoxin and tetrodotoxin‐binding protein genes in toxic and nontoxic pufferfishes
Published in Journal of evolutionary biology (01-05-2015)“…Understanding the evolutionary mechanisms of toxin accumulation in pufferfishes has been long‐standing problem in toxicology and evolutionary biology…”
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20
Primary Cutaneous Alveolar Rhabdomyosarcoma in an Elderly Adult: A Rare Potential Mimic of Merkel Cell Carcinoma
Published in The American journal of dermatopathology (01-03-2022)“…Rhabdomyosarcoma (RMS) rarely arises as a primary skin tumor. It is also very rare in older adults, especially the alveolar type. We report an 80-year-old…”
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