Search Results - "Mikheyev, Alexander S"
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An ancient, conserved gene regulatory network led to the rise of oral venom systems
Published in Proceedings of the National Academy of Sciences - PNAS (06-04-2021)“…Oral venom systems evolved multiple times in numerous vertebrates, enabling the exploitation of unique predatory niches. Yet how and when they evolved remains…”
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2
A first look at the Oxford Nanopore MinION sequencer
Published in Molecular ecology resources (01-11-2014)“…Oxford Nanopore's third‐generation single‐molecule sequencing platform promises to decrease costs for reagents and instrumentation. After a 2‐year hiatus…”
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Many Options, Few Solutions: Over 60 My Snakes Converged on a Few Optimal Venom Formulations
Published in Molecular biology and evolution (01-09-2019)“…Abstract Gene expression changes contribute to complex trait variations in both individuals and populations. However, the evolution of gene expression…”
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Honey Bee Larval and Adult Microbiome Life Stages Are Effectively Decoupled with Vertical Transmission Overcoming Early Life Perturbations
Published in mBio (21-12-2021)“…Microbiomes provide a range of benefits to their hosts which can lead to the coevolution of a joint ecological niche. However, holometabolous insects, some of…”
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A hybrid de novo genome assembly of the honeybee, Apis mellifera, with chromosome-length scaffolds
Published in BMC genomics (08-04-2019)“…The ability to generate long sequencing reads and access long-range linkage information is revolutionizing the quality and completeness of genome assemblies…”
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Toxin expression in snake venom evolves rapidly with constant shifts in evolutionary rates
Published in Proceedings of the Royal Society. B, Biological sciences (13-05-2020)“…Key innovations provide ecological opportunity by enabling access to new resources, colonization of new environments, and are associated with adaptive…”
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Ancestral diet transgenerationally influences offspring in a parent-of-origin and sex-specific manner
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (18-03-2019)“…Parent-of-origin effects, whereby specific phenotypes are differentially inherited paternally or maternally, provide useful clues to better understand…”
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Convergent eusocial evolution is based on a shared reproductive groundplan plus lineage-specific plastic genes
Published in Nature communications (14-06-2019)“…Eusociality has convergently evolved multiple times, but the genomic basis of caste-based division of labor and degree to which independent origins of…”
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Sodium Channel β Subunits-An Additional Element in Animal Tetrodotoxin Resistance?
Published in International journal of molecular sciences (01-02-2024)“…Tetrodotoxin (TTX) is a neurotoxic molecule used by many animals for defense and/or predation, as well as an important biomedical tool. Its ubiquity as a…”
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10
Vector-virus interaction affects viral loads and co-occurrence
Published in BMC biology (17-12-2022)“…Vector-borne viral diseases threaten human and wildlife worldwide. Vectors are often viewed as a passive syringe injecting the virus. However, to survive,…”
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11
Co-option of the same ancestral gene family gave rise to mammalian and reptilian toxins
Published in BMC biology (23-12-2021)“…Evolution can occur with surprising predictability when organisms face similar ecological challenges. For most traits, it is difficult to ascertain whether…”
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Comparative transcriptomics of social insect queen pheromones
Published in Nature communications (08-04-2019)“…Queen pheromones are chemical signals that mediate reproductive division of labor in eusocial animals. Remarkably, queen pheromones are composed of identical…”
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13
A toolkit for studying Varroa genomics and transcriptomics: preservation, extraction, and sequencing library preparation
Published in BMC genomics (14-01-2021)“…The honey bee parasite, Varroa destructor, is a leading cause of honey bee population declines. In addition to being an obligate ectoparasitic mite, Varroa…”
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14
Interactive web-based visualization and sharing of phylogenetic trees using phylogeny.IO
Published in Nucleic acids research (02-07-2019)“…Traditional static publication formats make visualization, exploration, and sharing of massive phylogenetic trees difficult. A phylogenetic study often…”
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15
Functional innovation promotes diversification of form in the evolution of an ultrafast trap-jaw mechanism in ants
Published in PLoS biology (02-03-2021)“…Evolutionary innovations underlie the rise of diversity and complexity-the 2 long-term trends in the history of life. How does natural selection redesign…”
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16
The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants
Published in Cell (10-08-2017)“…Social insects are emerging models to study how gene regulation affects behavior because their colonies comprise individuals with the same genomes but greatly…”
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17
Genomic Signature of Kin Selection in an Ant with Obligately Sterile Workers
Published in Molecular biology and evolution (01-07-2017)“…Kin selection is thought to drive the evolution of cooperation and conflict, but the specific genes and genome-wide patterns shaped by kin selection are…”
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Quantitative high-throughput profiling of snake venom gland transcriptomes and proteomes (Ovophis okinavensis and Protobothrops flavoviridis)
Published in BMC genomics (14-11-2013)“…Advances in DNA sequencing and proteomics have facilitated quantitative comparisons of snake venom composition. Most studies have employed one approach or the…”
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19
Genomic signatures of recent convergent transitions to social life in spiders
Published in Nature communications (22-11-2022)“…The transition from solitary to social life is a major phenotypic innovation, but its genetic underpinnings are largely unknown. To identify genomic changes…”
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Experimental inheritance of antibiotic acquired dysbiosis affects host phenotypes across generations
Published in Frontiers in microbiology (01-12-2022)“…Microbiomes can enhance the health, fitness and even evolutionary potential of their hosts. Many organisms propagate favorable microbiomes fully or partially…”
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