Search Results - "Mikhaylova, Valeriya V."
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1
Change in the Kinetic Regime of Aggregation of Yeast Alcohol Dehydrogenase in the Presence of 2-Hydroxypropyl-β-cyclodextrin
Published in International journal of molecular sciences (01-11-2023)“…Chemical chaperones are low-molecular-weight compounds that suppress protein aggregation. They can influence different stages of the aggregation process—the…”
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2
The Effect of Chemical Chaperones on Proteins with Different Aggregation Kinetics
Published in Biochemistry (Moscow) (2023)“…Formation and accumulation of protein aggregates adversely affect intracellular processes in living cells and are negative factors in the production and…”
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3
Effect of Chemical Chaperones on the Stability of Proteins during Heat- or Freeze-Thaw Stress
Published in International journal of molecular sciences (18-06-2023)“…The importance of studying the structural stability of proteins is determined by the structure-function relationship. Protein stability is influenced by many…”
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4
Effect of Betaine and Arginine on Interaction of αB-Crystallin with Glycogen Phosphorylase b
Published in International journal of molecular sciences (30-03-2022)“…Protein-protein interactions (PPIs) play an important role in many biological processes in a living cell. Among them chaperone-client interactions are the most…”
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5
Chaperone-Like Activity of HSPB5: The Effects of Quaternary Structure Dynamics and Crowding
Published in International journal of molecular sciences (13-07-2020)“…Small heat-shock proteins (sHSPs) are ATP-independent molecular chaperones that interact with partially unfolded proteins, preventing their aberrant…”
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6
Effect of Arginine on Chaperone-Like Activity of HspB6 and Monomeric 14-3-3ζ
Published in International journal of molecular sciences (16-03-2020)“…The effect of protein chaperones HspB6 and the monomeric form of the protein 14-3-3ζ (14-3-3ζ ) on a test system based on thermal aggregation of UV-irradiated…”
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7
A thermal after-effect of UV irradiation of muscle glycogen phosphorylase b
Published in PloS one (07-12-2017)“…Different test systems are used to characterize the anti-aggregation efficiency of molecular chaperone proteins and of low-molecular-weight chemical…”
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8
Effects of osmolytes under crowding conditions on the properties of muscle glycogen phosphorylase b
Published in Biochimie (01-05-2024)“…The study of the relationship between the activity and stability of enzymes under crowding conditions in the presence of osmolytes is important for…”
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9
Combined action of chemical chaperones on stability, aggregation and oligomeric state of muscle glycogen phosphorylase b
Published in International journal of biological macromolecules (01-04-2022)“…Chemical chaperones are a class of small molecules, which enhance protein stability, folding, inhibit protein aggregation, and are used for long-term storage…”
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10
Effect of arginine on stability and aggregation of muscle glycogen phosphorylase b
Published in International journal of biological macromolecules (15-12-2020)“…Arginine (Arg) is frequently used in biotechnology and pharmaceutics to stabilize protein preparations. When using charged ions like Arg, it is necessary to…”
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11
Effect of Trehalose on Oligomeric State and Anti-Aggregation Activity of αB-Crystallin
Published in Biochemistry (Moscow) (01-02-2022)“…αB-Crystallin (αB-Cr), one of the main crystalline lens proteins, along with other crystallins maintains lens transparency suppressing protein aggregation and…”
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12
Comparative effects of trehalose and 2-hydroxypropyl-β-cyclodextrin on aggregation of UV-irradiated muscle glycogen phosphorylase b
Published in Biochimie (01-10-2019)“…Chemical chaperones are a class of small molecules which enhance folding and prevent aggregation of proteins. Investigation of their effects on the processes…”
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13
Kinetic regime of thermal aggregation of holo- and apoglycogen phosphorylases b
Published in International journal of biological macromolecules (01-11-2016)“…[Display omitted] Kinetic regime of thermal aggregation of holo- and apoglycogen phosphorylases b has been analyzed.The rate-limiting stage for aggregation…”
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14
Oligomeric state of αB-crystallin under crowded conditions
Published in Biochemical and biophysical research communications (22-01-2019)“…Small heat shock proteins (sHsps) are molecular chaperones preventing protein aggregation. Dynamics of quaternary structure plays an important role in the…”
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15
Kinetic regime of Ca2+ and Mg2+-induced aggregation of phosphorylase kinase at 40 °C
Published in International journal of biological macromolecules (01-10-2019)“…Many functions of phosphorylase kinase (PhK) are regulated by Ca2+ and Mg2+ ions. Ca2+ and Mg2+ ions stimulate activity of PhK, induce the changes in the…”
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16
Effect of ionic strength and arginine on aggregation of UV-irradiated muscle glycogen phosphorylase b
Published in International journal of biological macromolecules (15-10-2018)“…In this work the effect of ionic strength and arginine on the kinetics of aggregation of UV-irradiated muscle glycogen phosphorylase b (UV-Phb) was studied…”
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17
Mechanism of aggregation of UV-irradiated glycogen phosphorylase b at a low temperature in the presence of crowders and trimethylamine N-oxide
Published in Biophysical chemistry (01-01-2018)“…To characterize the initial stages of protein aggregation, the kinetics of aggregation of UV-irradiated glycogen phosphorylase b (UV-Phb) was studied under…”
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18
Checking for reversibility of aggregation of UV-irradiated glycogen phosphorylase b under crowding conditions
Published in International journal of biological macromolecules (01-05-2016)“…[Display omitted] UV-irradiated Phb (UVPhb) is a convenient target protein for the study of the initial stages of aggregation process.UVPhb aggregation…”
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19
Dual effect of arginine on aggregation of phosphorylase kinase
Published in International journal of biological macromolecules (01-07-2014)“…Arginine is widely used in biotechnology as a folding enhancer and aggregation suppressor. However, its action on the stability of complexly organized…”
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20
Effect of Trehalose on Oligomeric State and Anti-Aggregation Activity of [alpha]B-Crystallin
Published in Biochemistry (Moscow) (01-02-2022)“…[alpha]B-Crystallin ([alpha]B-Cr), one of the main crystalline lens proteins, along with other crystallins maintains lens transparency suppressing protein…”
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