Search Results - "Mikesch, Kristina"

Evidence for idiotype-directed immunosurveillance is restricted to follicular lymphoma and attributable to somatic hypermutation by Papaioannou, Dimitrios, Strothmeyer, Anna-Maria, Dühren-von Minden, Marcus, Keppler-Hafkemeyer, Andrea, Zirlik, Katja, Mikesch, Kristina, van Bergen, Cornelis A M, Navarrete, Marcelo A, Veelken, Hendrik

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Cloning of idiotype immunoglobulin genes in B cell lymphomas by anchored PCR and production of individual recombinant idiotype vaccines in Escherichia coli by Bertinetti, Cristina, Simon, Frederic, Zirlik, Katja, Heining-Mikesch, Kristina, Pfeifer, Dietmar, Osterroth, Frank, Rosenthal, Felicia M., Veelken, Hendrik

“…:  Objectives: Individual immunoglobulins expressed by B‐cell lymphomas represent tumor‐specific antigens (‘idiotypes’). Immunization with idiotype in…”
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Cetuximab, docetaxel, and cisplatin versus platinum, fluorouracil, and cetuximab as first-line treatment in patients with recurrent or metastatic head and neck squamous-cell carcinoma (GORTEC 2014-01 TPExtreme): a multicentre, open-label, randomised, phase 2 trial by Guigay, Joël, Fayette, Jérôme, Saada-Bouzid, Esma, Martin, Laurent, Capitain, Olivier, Castanie, Hélène, Vansteene, Damien, Schafhausen, Philippe, Johnson, Alison, Even, Caroline, Duplomb, Sophie, Evrard, Camille, Laguerre, Brigitte, Chevassus-Clément, Cécile, Sinigaglia, Laura, Keilholz, Ulrich, Bourhis, Jean, Mesia, Ricard, BABA-HAMED, Nabil, BABIN, Emmanuel, BERA, Guillaume, BETRIAN-LAGARDE, Sarah, BLOT, Emmanuel, BOREL, Christian, BRUYAS, Amandine, CALAIS, Gilles, CARPIUC, Ioana, CHAPET, Sophie, CHATELLIER, Thierry, CHELI, Sandrine, CLATOT, Florian, COJOCARASU, Oana, COUTTE, Alexandre, DALLOZ, Pierre, DELHOMMEAU, Melissa, DE RAUCOURT, Dominique, DEBOURDEAU, Philippe, DUBOS-ARVIS, Catherine, DUCOULOMBIER, Agnès, EL KOURI, Claude, FALKOWSKI, Sabrina, FERRAND, François-Regis, GATINEAU, Michel, GERVAIS, Radj, GRAS, Louis, HASBINI, Ali, HENAULT, Stéphane, HERRERA GOMEZ, Ruth Gabriela, HUGUET, Florence, LAGRANGE, Aurélie, LE FOLL, Christine, LINOT, Benjamin, LOPEZ, Qian, MAYACHE-BADIS, Lamia, MINNE, Floriane, NEIDHARDT, Eve Marie, PAVILLET, Julien, PEYRADE, Frédéric, POINTREAU, Yohann, RAMEE, Jean-François, RAUCHE, Camille, RICHARD, Sandrine, RIZZO, Claudia, ROLLAND, Frédéric, STEFANI, Laetitia, THERY, Jean-Christophe, TOULLEC, Clémence, TOURANI, Jean-Marc, TOUSSAINT, Philippe, VAULEON, Elodie, VIRET, Frédéric, WALER, Sabine, ATZPODIEN, Jens, FIETKAU, Rainer, GRANIZKA, Thordis, GUNTINAS-LICHINUS, Orlando, HADLER-MIKESCH, Kristina, HAHN, Dennis, INHESTERN, Johanna, KELLNER, Karolin, KLINGHAMMER, Konrad, KRONENBERGER, Roland, LUEDTKE-HECKENKAMP, Kerstin, PIRLICH, Markus, ROTHMANN, Frank, TOMETTEN, Mareike, WOHLFARTH, Sabine, ZEBRALLA, Veit, ZIPFEL, Matthias, ADANSA KLEIN, Juan Carlos, ARRAZUBI, Virginia, CABALLERO DAROQUI, Javier, CASTELO, Beatriz, GALLEGO, Oscar, IGLESIAS DOCAMPO, Lara Carmen, MARTINEZ DEL PRADO, Maria, MARTINEZ-TRUFERO, Javier, PASTOR BORGONON, Miguel, PEREZ RUIZ, Elisabeth, RUBIO CASADEVALL, Jordi

“…Results from a phase 2 trial of the TPEx chemotherapy regimen (docetaxel–platinum–cetuximab) showed promising results, with a median overall survival of 14·0…”
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High-dose chemotherapy and autologous stem cell transplant compared with conventional chemotherapy for consolidation in newly diagnosed primary CNS lymphoma--a randomized phase III trial (MATRix) by Schorb, Elisabeth, Finke, Juergen, Ferreri, Andrés J M, Ihorst, Gabriele, Mikesch, Kristina, Kasenda, Benjamin, Fritsch, Kristina, Fricker, Heidi, Burger, Elvira, Grishina, Olga, Valk, Elke, Zucca, Emanuele, Illerhaus, Gerald

“…Primary central nervous system lymphoma (PCNSL) is a highly aggressive Non-Hodgkin lymphoma (NHL) with rising incidence over the past 30 years in…”
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Thymic Carcinoma with Overexpression of Mutated KIT and the Response to Imatinib by Mikesch, Kristina, Marx, Alexander, Dirnhofer, Stefan, Ströbel, Philipp, Jakob, Andreas, Hartmann, Martina, Brink, Ingo

“…To the Editor: In April 2002, a 54-year-old man presented with thoracic pain and respiratory distress; a mediastinal mass, 7.7 by 6 cm, was found on…”
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Selection patterns of B‐cell receptors and the natural history of follicular lymphoma by Scherer, Florian, Burgt, Marlon, Kiełbasa, Szymon M., Bertinetti‐Lapatki, Cristina, Dühren von Minden, Marcus, Mikesch, Kristina, Zirlik, Katja, Wreede, Liesbeth, Veelken, Hendrik, Navarrete, Marcelo A.

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Upfront immunization with autologous recombinant idiotype Fab fragment without prior cytoreduction in indolent B-cell lymphoma by Navarrete, Marcelo A., Heining-Mikesch, Kristina, Schüler, Frank, Bertinetti-Lapatki, Cristina, Ihorst, Gabriele, Keppler-Hafkemeyer, Andrea, Dölken, Gottfried, Veelken, Hendrik

“…Idiotype vaccination for follicular lymphoma is primarily being developed as remission consolidation after chemotherapy. We investigated idiotype vaccination…”
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Comparative analysis of predicted HLA binding of immunoglobulin idiotype sequences indicates T cell–mediated immunosurveillance in follicular lymphoma by Strothmeyer, Anna-Maria, Papaioannou, Dimitrios, Dühren-von Minden, Marcus, Navarrete, Marcelo, Zirlik, Katja, Heining-Mikesch, Kristina, Veelken, Hendrik

“…Active immunization with the idiotype of follicular lymphoma induces tumor-specific immunity. T cells induced in vivo by idiotype vaccination recognize human…”
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Prediction of MHC Class I-Restricted Immunogenic Epitopes of B-Cell Receptors Indicates T Cell-Mediated Immunosurveillance of Malignant B Cell Clones by Strothmeyer, Anna-Maria, Duehren-von Minden, Marcus, Navarrete, Marcelo A, Heining-Mikesch, Kristina, Veelken, Hendrik

“…Abstract 1949 Poster Board I-972 Tumor-specific immune responses can be induced in patients with indolent B cell lymphomas (iNHL) by active immunization…”
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High-Throughput Analysis of Antigen Recognition by the B Cell Receptors of Malignant Lymphomas with High-Density Protein Microarrays by Frick, Mareike, Bulashevska, Alla, Duehren-von Minden, Marcus, Heining-Mikesch, Kristina, Pfeifer, Dietmar, Veelken, Hendrik

“…Abstract 2945 Poster Board II-921 The etiology of indolent B cell lymphomas (iNHL) is largely unknown. However, systemic autoimmune diseases are associated…”
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Phase I trial of a novel intradermal idiotype vaccine in patients with advanced B-cell lymphoma : Specific immune responses despite profound immunosuppression by BERTINETTI, Cristina, ZIRLIK, Katja, HEINING-MIKESCH, Kristina, IHORST, Gabriele, DIERBACH, Heide, WALLER, Cornelius F, VEELKEN, Hendrik

“…The immunoglobulin receptor of B-cell lymphomas constitutes a specific tumor antigen (idiotype) and a target for active immunotherapy. Encouraging results have…”
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HLA-Dependent Immune Selection Pressure on the Idiotype Is Predominantly Driven by Somatic Hypermutation In Malignant Lymphoma but Also Modulates Vh Usage In Normal B Cells by Papaioannou, Dimitrios, Strothmeyer, Anna-Maria, Minden, Marcus Dühren-von, Navarrete, Marcelo A., Zirlik, Katja, Heining-Mikesch, Kristina, Veelken, Hendrik

“…Abstract 3132 The idiotype (Id) of malignant lymphomas is a tumor-specific antigen and has been evaluated for active immunotherapy predominantly in follicular…”
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Idiotype Vaccination of Untreated Indolent B-Cell Lymphoma: Durable Objective Remissions and Association of Superior Outcome with Cellular Immune Responses by Navarrete, Marcelo A., Heining-Mikesch, Kristina, Bertinetti-Lapatki, Cristina, Duehren-von Minden, Marcus, Hafkemeyer, Andrea, Veelken, Hendrik

“…Idiotype vaccination refers to active immunization of B-cell lymphoma (B-NHL) patients with the clonal immunoglobulin (Ig) expressed by the tumor cells. After…”
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Kinetics of Immune Responses and Tumor Burden in Patients with Indolent B Cell Lymphomas Receiving Recombinant Idiotype Vaccination as the Sole Treatment by Bertinetti, Cristina, Schueler, Frank, Heining-Mikesch, Kristina, Zirlik, Katja, Tomann, Tina, Franke, Brigitte, Dolken, Gottfried, Veelken, Hendrik

“…Immunization of patients with B-cell non-Hodgkin's lymphoma with the individual idiotype expressed by the malignant clone can induce tumor-specific immune…”
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Cloning of Idiotype Immunoglobulin Genes in B Cell Lymphomas by Anchored PCR and Production of Individual Recombinant Idiotype Vaccines in E. coli by Bertinetti, Cristina, Simon, Frederic, Reinhardt, Jana, Mauerer, Katja, Mikesch, Kristina, Rosenthal, Felicia M., Veelken, Hendrik

“…The hypervariable regions (idiotypes) of the immunoglobulins (Ig) expressed by lymphoma cells represent individual and specific tumor antigens. Purified or…”
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Extramedullary plasmocytoma with local amyloidosis presenting as a lump on the lip by Zeiser, Robert, Mikesch, Kristina, Fisch, Paul, Schaefer, Hans‐Eckart, Burger, Jan A.

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Thymic carcinoma with overexpression of mutated KIT and the response to imatinib by Ströbel, Philipp, Hartmann, Martina, Jakob, Andreas, Mikesch, Kristina, Brink, Ingo, Dirnhofer, Stefan, Marx, Alexander

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