Search Results - "Mike, Agnes K"
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Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart
Published in PloS one (23-05-2011)“…Duchenne muscular dystrophy (DMD), caused by mutations in the dystrophin gene, is associated with severe cardiac complications including cardiomyopathy and…”
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Small Molecule Cardiogenol C Upregulates Cardiac Markers and Induces Cardiac Functional Properties in Lineage-Committed Progenitor Cells
Published in Cellular physiology and biochemistry (01-01-2014)“…Background/Aims: Cell transplantation into the heart is a new therapy after myocardial infarction. Its success, however, is impeded by poor donor cell survival…”
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Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile
Published in Toxicology and applied pharmacology (01-12-2013)“…The plant alkaloid ibogaine has promising anti-addictive properties. Albeit not licenced as a therapeutic drug, and despite hints that ibogaine may perturb the…”
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Analysis of travel restrictions for COVID-19 control in Latin America through network connectedness
Published in Journal of travel medicine (23-12-2020)“…We analyze the COVID-19 pandemic development in Latin America by network analysis to demonstrate the effectiveness of air travel restriction in reducing…”
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The First Crystal Structure of a Voltage-Gated Na+ Channel Predicts a New Determinant of External Access for Hydrophilic Local Anaesthetics
Published in Biophysical journal (29-01-2013)Get full text
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New structural determinants of charged local anaesthetic block of voltage-gated sodium channels
Published in BMC pharmacology & toxicology (17-09-2012)“…Doc number: A70…”
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A conformational change of the domain IV S6 segment of the voltage-gated sodium channel during inactivation
Published in BMC pharmacology & toxicology (17-09-2012)Get full text
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The anti-addiction drug ibogaine inhibits cardiac ion channels: a study to assess the drug’s proarrhythmic potential
Published in BMC pharmacology & toxicology (17-09-2012)Get full text
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Impaired L-type Ca2+ channel function in the dystrophic heart
Published in BMC pharmacology & toxicology (17-09-2012)Get full text
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