Search Results - "Mikami, Hirofumi"

Gene amplification: mechanisms and involvement in cancer by Matsui Atsuka, Ihara Tatsuya, Suda Hiraku, Mikami Hirofumi, Semba Kentaro

“…Gene amplification was recognized as a physiological process during the development of Drosophila melanogaster. Intriguingly, mammalian cells use this…”
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A method of producing genetically manipulated mouse mammary gland by Tagaya, Hiroaki, Ishikawa, Kosuke, Hosokawa, Yoshito, Kobayashi, Shun, Ueoka, Yukino, Shimada, Mayuna, Ohashi, Yasuko, Mikami, Hirofumi, Yamamoto, Mizuki, Ihara, Tatsuya, Kumazawa, Kentaro, Sugihara, Kosuke, Goshima, Naoki, Watanabe, Shinya, Semba, Kentaro

“…To obtain a deep understanding of the mechanism by which breast cancer develops, the genes involved in tumorigenesis should be analyzed in vivo. Mouse mammary…”
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Abstract 5518: Single cell RNA sequencing revealed that the mechanism of the synergistic efficacy of STA551 and immune checkpoint inhibitor results from the induction of highly activated T cells in tumor by Uchikawa, Ryo, Takakuwa, Kazuya, Mikami, Hirofumi, Metsugi, Shoichi, Taniguchi, Kenji, Narita, Yoshinori, Kamata-Sakurai, Mika

“…Abstract Background: CD137 (4-1BB) is a co-stimulatory molecule which exerts activation signals in multiple immune cell subsets. However, agonist antibodies…”
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Engineering CD3/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer by Mikami, Hirofumi, Feng, Shu, Matsuda, Yutaka, Ishii, Shinya, Naoi, Sotaro, Azuma, Yumiko, Nagano, Hiroaki, Asanuma, Kentaro, Kayukawa, Yoko, Tsunenari, Toshiaki, Kamikawaji, Shogo, Iwabuchi, Ryutaro, Shinozuka, Junko, Yamazaki, Masaki, Kuroi, Haruka, Ho, Samantha Shu Wen, Gan, Siok Wan, Chichili, Priyanka, Pang, Chai Ling, Yeo, Chiew Ying, Shimizu, Shun, Hironiwa, Naoka, Kinoshita, Yasuko, Shimizu, Yuichiro, Sakamoto, Akihisa, Muraoka, Masaru, Takahashi, Noriyuki, Kawa, Tatsuya, Shiraiwa, Hirotake, Mimoto, Futa, Kashima, Kenji, Kamata-Sakurai, Mika, Ishikawa, Shumpei, Aburatani, Hiroyuki, Kitazawa, Takehisa, Igawa, Tomoyuki

“…Small-cell lung cancer (SCLC) is an aggressive cancer for which immune checkpoint inhibitors (ICI) have had only limited success. Bispecific T-cell engagers…”
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Abstract 1872: A DLL3/CD3/CD137 trispecific T cell engager shows potent antitumor activity in small cell lung cancer models by Mikami, Hirofumi, Feng, Shu, Naoi, Sotaro, Azuma, Yumiko, Kayukawa, Yoko, Tsunenari, Toshiaki, Asanuma, Kentaro, Iwabuchi, Ryutaro, Nagano, Hiroaki, Shinozuka, Junko, Yamazaki, Masaki, Kuroi, Haruka, Gan, Siok Wan, Chichili, Priyanka, Shimizu, Shun, Matsuda, Yutaka, Ishii, Shinya, Kamikawaji, Shogo, Kinoshita, Yasuko, Shimizu, Yuichiro, Sakamoto, Akihisa, Muraoka, Masaru, Takahashi, Noriyuki, Kawa, Tatsuya, Shiraiwa, Hirotake, Kashima, Kenji, Mimoto, Futa, Kamata-Sakurai, Mika, Kitazawa, Takehisa, Igawa, Tomoyuki

“…Abstract Background: Despite the approval of immune checkpoint inhibitors (ICIs), prognosis of small cell lung cancer (SCLC) remains poor. DLL3 is upregulated…”
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Gene amplification: mechanisms and involvement in cancer by Matsui, Atsuka, Ihara, Tatsuya, Suda, Hiraku, Mikami, Hirofumi, Semba, Kentaro

“…Gene amplification was recognized as a physiological process during the development of Drosophila melanogaster. Intriguingly, mammalian cells use this…”
Get more information