Search Results - "Mikami, Ayako"
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Correlates of neutralizing/SARS-CoV-2-S1-binding antibody response with adverse effects and immune kinetics in BNT162b2-vaccinated individuals
Published in Scientific reports (24-11-2021)“…While mRNA vaccines against SARS-CoV-2 are exceedingly effective in preventing symptomatic infection, their immune response features remain to be clarified. In…”
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Inhaled GM-CSF for Pulmonary Alveolar Proteinosis
Published in The New England journal of medicine (05-09-2019)“…In patients with autoimmune pulmonary alveolar proteinosis, the use of inhaled recombinant granulocyte–macrophage colony-stimulating factor resulted in a…”
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Mechanisms for the α-Adrenoceptor-Mediated Positive Inotropy in Mouse Ventricular Myocardium: Enhancing Effect of Action Potential Prolongation
Published in International journal of molecular sciences (15-02-2023)“…Mechanisms for the α-adrenoceptor-mediated positive inotropy in neonatal mouse ventricular myocardium were studied with isolated myocardial preparations. The…”
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Clinical trial experience in Japan and future issues in developing drugs to treat COVID-19
Published in Global Health & Medicine (30-04-2023)“…The National Center for Global Health and Medicine plays a central role in the treatment and research of infectious diseases in Japan. It has conducted various…”
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Major ongoing clinical trials for COVID-19 treatment and studies currently being conducted or scheduled in Japan
Published in Global Health & Medicine (30-04-2020)“…The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a serious threat to global…”
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Energy-Saving and CO2-Emissions-Reduction Potential of a Fuel Cell Cogeneration System for Condominiums Based on a Field Survey
Published in Energies (Basel) (01-10-2021)“…A residential cogeneration system (CGS) is highlighted because of its efficient energy usage on both the supplier and consumer sides. It generates electricity…”
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Field Study on Energy-Saving Behaviour and Patterns of Air-Conditioning Use in a Condominium
Published in Energies (Basel) (01-12-2021)“…In the international movement to combat the threat of climate change, the timely implementation of residential energy-saving practises is becoming an urgent…”
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Impact of inhaled ciclesonide on asymptomatic or mild COVID-19: A randomized trial
Published in Drug Discoveries & Therapeutics (31-10-2022)“…The aim of this study was to determine the efficacy and safety of ciclesonide in the treatment of novel coronavirus disease 2019 (COVID-19) as gauged by…”
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Immunogenicity and safety of single booster dose of KD-414 inactivated COVID-19 vaccine in adults: An open-label, single-center, non-randomized, controlled study in Japan
Published in Human vaccines & immunotherapeutics (31-12-2023)“…Although vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease 2019 (COVID-19) induce effective immune responses, vaccination with…”
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Investigator initiated clinical trial of remdesivir for the treatment of COVID-19 in Japan
Published in Global Health & Medicine (30-04-2021)“…Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originating in Wuhan, China, has spread globally very…”
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Inhaled GM-CSF for Pulmonary Alveolar Proteinosis
Published in The New England journal of medicine (05-09-2019)Get full text
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12
Efficacy of convalescent plasma therapy for COVID-19 in Japan: An open-label, randomized, controlled trial
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-09-2023)“…Convalescent plasma is a potential therapeutic option for patients with coronavirus disease 2019 (COVID-19). Despite its use for treating several viral…”
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Efficacy and Safety of Direct Hemoperfusion Using Polymyxin B-Immobilized Polystyrene Column for Patients With COVID-19: Protocol for an Exploratory Study
Published in JMIR research protocols (01-11-2022)“…Background Polymyxin B-immobilized fiber column (PMX; Toraymyxin column) was approved for the relief of systemic inflammatory response syndrome caused by…”
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Protocol of an Exploratory Single-Arm Study to Evaluate the Safety and Immunogenicity of KD-414 as a Booster Vaccine for SARS-CoV-2 in Healthy Adults (KAPIVARA)
Published in Life (Basel, Switzerland) (27-06-2022)“…The coronavirus disease 2019 (COVID-19) pandemic is currently ongoing, and there have been significant efforts in the development of COVID-19 vaccines…”
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A Multi-Center, Open-Label, Randomized Controlled Trial to Evaluate the Efficacy of Convalescent Plasma Therapy for Coronavirus Disease 2019: A Trial Protocol (COVIPLA-RCT)
Published in Life (Basel, Switzerland) (08-06-2022)“…Coronavirus disease 2019 is a global public health concern. As of December 2020, the therapeutic agents approved for coronavirus disease 2019 in Japan were…”
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Benefit of extending the dosing interval of long‐acting antipsychotic injections in elderly schizophrenics with cognitive dysfunction
Published in Psychogeriatrics (01-11-2017)Get full text
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Validation of a new serum granulocyte-macrophage colony-stimulating factor autoantibody testing kit
Published in ERJ open research (01-01-2020)“…Very recently, a modest but significant efficacy of granulocyte-macrophage colony-stimulating factor (GM-CSF) inhalation therapy for the treatment of mild to…”
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Benefits associated with switching from benzodiazepine hypnotics to suvorexant in patients with mild primary insomnia
Published in Asian journal of psychiatry (01-10-2017)Get full text
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Study of the efficacy and safety of switching from risperidone to paliperidone in elderly patients with schizophrenia
Published in Psychiatry and clinical neurosciences (01-02-2013)“…Aim We investigated the clinical efficacy and safety of switching to paliperidone (PAL) in elderly schizophrenia patients receiving risperidone. Methods The…”
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Synthesis and structure–activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
Published in Bioorganic & medicinal chemistry (01-04-2008)“…We report the identification of a potent and stable DPP-IV inhibitor (TS-021) with a long-term persistent plasma drug concentration and a potent…”
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