Search Results - "Mikaelian, I."

Unbalanced expression of CK2 kinase subunits is sufficient to drive epithelial-to-mesenchymal transition by Snail1 induction by Deshiere, A, Duchemin-Pelletier, E, Spreux, E, Ciais, D, Combes, F, Vandenbrouck, Y, Couté, Y, Mikaelian, I, Giusiano, S, Charpin, C, Cochet, C, Filhol, O

“…Epithelial-to-mesenchymal transition (EMT) is closely linked to conversion of early-stage tumours into invasive malignancies. Many signalling pathways are…”
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Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik by Lopez, J, Hesling, C, Prudent, J, Popgeorgiev, N, Gadet, R, Mikaelian, I, Rimokh, R, Gillet, G, Gonzalo, P

“…Src, the canonical member of the non-receptor family of tyrosine kinases, is deregulated in numerous cancers, including colon and breast cancers. In addition…”
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Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype by Grelier, G, Voirin, N, Ay, A-S, Cox, D G, Chabaud, S, Treilleux, I, Léon-Goddard, S, Rimokh, R, Mikaelian, I, Venoux, C, Puisieux, A, Lasset, C, Moyret-Lalle, C

“…Background: Dicer, a ribonuclease, is the key enzyme required for the biogenesis of microRNAs and small interfering RNAs and is essential for both mammalian…”
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A liver-targeted acetyl CoA carboxylase inhibitor reduces hepatic steatosis and liver injury in a murine model of NASH by Bates, J, Brockett, R, Mikaelian, I, Wang, T, Ray, A, Tumas, D, Breckenridge, D

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Proposal of Bisgaardia hudsonensis gen. nov., sp. nov. and an additional genomospecies, isolated from seals, as new members of the family Pasteurellaceae by Foster, G, Higgins, R, Leclair, D, Korczak, B. M, Mikaelian, I, Patterson, I. A. P, Kuhnert, P

“…Phenotypic and phylogenetic studies were performed on eight Gram-negative-staining, rod-shaped bacteria isolated from seals. Biochemical and physiological…”
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LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation by Malek, M, Guillaumot, P, Huber, A-L, Lebeau, J, Pétrilli, V, Kfoury, A, Mikaelian, I, Renno, T, Manié, S N

“…Lysosomal regulation is a poorly understood mechanism that is central to degradation and recycling processes. Here we report that LAMTOR1 (late…”
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Cutaneous Smooth Muscle Tumors in the Dog and Cat by Liu, S. M., Mikaelian, I.

“…Cutaneous smooth muscle tumors may arise from arrector pili muscles and from smooth muscles of the dermal vasculature. This report describes histologic and…”
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Expression of Terminal Differentiation Proteins Defines Stages of Mouse Mammary Gland Development by Mikaelian, I, Hovick, M, Silva, K. A, Burzenski, L. M, Shultz, L. D, Ackert-Bicknell, C. L, Cox, G. A, Sundberg, J. P

“…Immunohistochemical analysis using paraffin-embedded specimens is the method of choice to evaluate protein expression at a cellular level while preserving…”
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Serum cardiac troponin I concentrations transiently increase in rats given rosiglitazone by Mikaelian, I., Buness, A., Hirkaler, G., Fernandes, R., Coluccio, D., Geng, W., Visalli, T., Bachynsky, M.O., Berkofsky-Fessler, W., Kanwal, C., Hilton, H., Nicklaus, R., Hoflack, J.-C., Dunn, M., Sanders, M., Giron, M., Boyle, B.W., Singer, T., Dick, L. Suter

“…▶ Serum cTnI was increased in Wistar rats given 80 mg/kg rosiglitazone for 7 days. ▶ Transcriptomic profile was consistent with physiologic hypertrophy. ▶…”
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Feline Papillomas and Papillomaviruses by Sundberg, J. P., Van Ranst, M., Montali, R., Homer, B. L., Miller, W. H., Rowland, P. H., Scott, D. W., England, J. J., Dunstan, R. W., Mikaelian, I., Jenson, A. B.

“…Papillomaviruses (PVs) are highly species- and site-specific pathogens of stratified squamous epithelium. Although PV infections in the various Felidae are…”
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Follicular Stem Cell Carcinoma: Histologic, Immunohistochemical, Ultrastructural, and Clinical Characterization in 30 Dogs by Mikaelian, I., Wong, V.

“…Diagnostic records of 30 primary and one metastatic follicular stem cell carcinomas in 30 dogs were reviewed. Neoplastic cells had a clear cytoplasm and formed…”
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Adenomatous Hyperplasia of the Thyroid Gland in Beluga Whales (Delphinapterus leucas) from the St. Lawrence Estuary and Hudson Bay, Quebec, Canada by Mikaelian, I., Labelle, P., Kopal, M., De Guise, S., Martineau, D.

“…We evaluated thyroid gland lesions in beluga whales (Delphinapterus leucas) from the St. Lawrence Estuary (n = 16) and Hudson Bay (n = 14). Follicular cysts…”
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"Follicular stem cell carcinoma: histologic, immunohistochemical, ultrastructural, and clinical characterization in 30 days" by Mikaelian, I, Wong, V

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Keloidal Fibromas and Fibrosarcomas in the Dog by Mikaelian, I., Gross, T. L.

“…Sixteen dogs (2–12 years of age) presented with one (n = 15) or two (n = 1) cutaneous nodules (n = 16) or a dermal plaque (n = 1). Intact males (n = 9) and…”
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ALK7 expression in prolactinoma is associated with reduced prolactin and increased proliferation by Principe, M, Chanal, M, Karam, V, Wierinckx, A, Mikaélian, I, Gadet, R, Auger, C, Raverot, V, Jouanneau, E, Vasiljevic, A, Hennino, A, Raverot, G, Bertolino, P

“…Prolactinoma represents the most frequent hormone-secreting pituitary tumours. These tumours appear in a benign form, but some of them can reach an invasive…”
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Toxoplasmosis in beluga whales (Delphinapterus leucas) from the St Lawrence estuary: two case reports and a serological survey by Mikaelian, I, Boisclair, J, Dubey, J.P, Kennedy, S, Martineau, D

“…Toxoplasmosis was diagnosed in two free-ranging beluga whales from the St Lawrence estuary, Quebec, Canada, in 1988 and 1998. Histologically, tachyzoites and…”
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Seroprevalence of Antibodies to Toxoplasma gondii in Lynx (Lynx canadensis) and Bobcats (Lynx rufus) From Québec, Canada by Labelle, P, Dubey, J. P, Mikaelian, I, Blanchette, N, Lafond, R, St-Onge, S, Martineau, D

“…The seroprevalence of antibodies to Toxoplasma gondii was investigated in trapped lynx (Lynx canadensis) and bobcats (Lynx rufus) from Québec, Canada…”
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Isolation of Ornithobacterium rhinotracheale from turkeys in Quebec, Canada by Joubert, P, Higgins, R, Laperle, A, Mikaelian, I, Venne, D, Silim, A

“…In the spring of 1997, three large white hybrid turkey layer flocks of 52 wk of age experienced a severe respiratory condition. During the outbreak, the…”
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Severe Hepatitis Resulting from Toxoplasmosis in a Barred Owl (Strix varia) from Québec, Canada by Mikaelian, I., Dubey, J. P., Martineau, D.

“…A female adult barred owl (Strix varia) had been hurt by a car. Its general status declined gradually within 2 wk with anorexia and inactivity. Necropsy…”
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Modification of the overlap extension method for extensive mutagenesis on the same template by Mikaelian, I, Sergeant, A

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