Search Results - "Mika, Kaakinen"

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  1. 1

    Presence of distinctive microbiome in the first-pass meconium of newborn infants by Turunen, Jenni, Tejesvi, Mysore V., Paalanne, Niko, Hekkala, Jenni, Lindgren, Outi, Kaakinen, Mika, Pokka, Tytti, Kaisanlahti, Anna, Reunanen, Justus, Tapiainen, Terhi

    Published in Scientific reports (30-09-2021)
    “…We critically evaluated the fetal microbiome concept in 44 neonates with placenta, amniotic fluid, and first-pass meconium samples. Placental histology showed…”
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    Journal Article
  2. 2

    Characterization of nucleic acids from extracellular vesicle-enriched human sweat by Bart, Geneviève, Fischer, Daniel, Samoylenko, Anatoliy, Zhyvolozhnyi, Artem, Stehantsev, Pavlo, Miinalainen, Ilkka, Kaakinen, Mika, Nurmi, Tuomas, Singh, Prateek, Kosamo, Susanna, Rannaste, Lauri, Viitala, Sirja, Hiltunen, Jussi, Vainio, Seppo J

    Published in BMC genomics (09-06-2021)
    “…The human sweat is a mixture of secretions from three types of glands: eccrine, apocrine, and sebaceous. Eccrine glands open directly on the skin surface and…”
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    Journal Article
  3. 3

    High Adherence of Oral Streptococcus to Polylactic Acid Might Explain Implant Infections Associated with PLA Mesh Implantation by Sarfraz, Sonia, Tamminen, Anni-Maria, Leikola, Junnu, Salmi, Sonja, Kaakinen, Mika, Sorsa, Timo, Suojanen, Juho, Reunanen, Justus

    “…The aim of this study was to evaluate and compare the biofilm formation properties of common pathogens associated with implant-related infections on two…”
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    Journal Article
  4. 4

    EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity by Frye, Maike, Stritt, Simon, Ortsäter, Henrik, Hernandez Vasquez, Magda, Kaakinen, Mika, Vicente, Andres, Wiseman, John, Eklund, Lauri, Martínez-Torrecuadrada, Jorge L, Vestweber, Dietmar, Mäkinen, Taija

    Published in eLife (08-09-2020)
    “…Endothelial integrity is vital for homeostasis and adjusted to tissue demands. Although fluid uptake by lymphatic capillaries is a critical attribute of the…”
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    Journal Article
  5. 5

    Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner by Richards, Mark, Nwadozi, Emmanuel, Pal, Sagnik, Martinsson, Pernilla, Kaakinen, Mika, Gloger, Marleen, Sjöberg, Elin, Koltowska, Katarzyna, Betsholtz, Christer, Eklund, Lauri, Nordling, Sofia, Claesson-Welsh, Lena

    Published in eLife (21-07-2022)
    “…Dysfunctional and leaky blood vessels resulting from disruption of the endothelial cell (EC) barrier accompanies numerous diseases. The EC barrier is…”
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    Journal Article
  6. 6

    Angiopoietin-4-dependent venous maturation and fluid drainage in the peripheral retina by Elamaa, Harri, Kihlström, Minna, Kapiainen, Emmi, Kaakinen, Mika, Miinalainen, Ilkka, Ragauskas, Symantas, Cerrada-Gimenez, Marc, Mering, Satu, Nätynki, Marjut, Eklund, Lauri

    Published in eLife (16-11-2018)
    “…The maintenance of fluid homeostasis is necessary for function of the neural retina; however, little is known about the significance of potential fluid…”
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    Journal Article
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    PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis by Elamaa, Harri, Kaakinen, Mika, Nätynki, Marjut, Szabo, Zoltan, Ronkainen, Veli-Pekka, Äijälä, Ville, Mäki, Joni M., Kerkelä, Risto, Myllyharju, Johanna, Eklund, Lauri

    Published in Angiogenesis (London) (01-05-2022)
    “…Hypoxia plays an important regulatory role in the vasculature to adjust blood flow to meet metabolic requirements. At the level of gene transcription, the…”
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    Journal Article
  9. 9

    Loss of α6β4 Integrin-Mediated Hemidesmosomes Promotes Prostate Epithelial Cell Migration by Stimulating Focal Adhesion Dynamics by Schmidt, Anette, Kaakinen, Mika, Wenta, Tomasz, Manninen, Aki

    “…Epithelial cell adhesion is mediated by actin cytoskeleton-linked focal adhesions (FAs) and intermediate filament-associated hemidesmosomes (HDs). HDs are…”
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    Journal Article
  10. 10

    Blood pressure lowering enhances cerebrospinal fluid efflux to the systemic circulation primarily via the lymphatic vasculature by Jukkola, Jari, Kaakinen, Mika, Singh, Abhishek, Moradi, Sadegh, Ferdinando, Hany, Myllylä, Teemu, Kiviniemi, Vesa, Eklund, Lauri

    Published in Fluids and barriers of the CNS (26-01-2024)
    “…Inside the incompressible cranium, the volume of cerebrospinal fluid is directly linked to blood volume: a change in either will induce a compensatory change…”
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    Journal Article
  11. 11

    Mortalin antibody-conjugated quantum dot transfer from human mesenchymal stromal cells to breast cancer cells requires cell–cell interaction by Pietilä, Mika, Lehenkari, Petri, Kuvaja, Paula, Kaakinen, Mika, Kaul, Sunil C., Wadhwa, Renu, Uemura, Toshimasa

    Published in Experimental cell research (01-11-2013)
    “…The role of tumor stroma in regulation of breast cancer growth has been widely studied. However, the details on the type of heterocellular cross-talk between…”
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    Journal Article
  12. 12

    New immunohistochemical method for improved myotonia and chloride channel mutation diagnostics by RAHEEM, Olayinka, PENTTILÄ, Sini, METSIKKÖ, Kalervo, HANNA, Michael, UDD, Bjarne, SUOMINEN, Tiina, KAAKINEN, Mika, BURGE, James, HAWORTH, Andrea, SUD, Richa, SCHORGE, Stephanie, HAAPASALO, Hannu, SANDELL, Satu

    Published in Neurology (27-11-2012)
    “…The objective of this study was to validate the immunohistochemical assay for the diagnosis of nondystrophic myotonia and to provide full clarification of…”
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    Journal Article
  13. 13

    Caveolin 3, Flotillin 1 and Influenza Virus Hemagglutinin Reside in Distinct Domains on the Sarcolemma of Skeletal Myofibers by Kaakinen, Mika, Kaisto, Tuula, Rahkila, Paavo, Metsikkö, Kalervo

    Published in Biochemistry Research International (01-01-2012)
    “…We examined the distribution of selected raft proteins on the sarcolemma of skeletal myofibers and the role of cholesterol environment in the distribution…”
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    Journal Article
  14. 14

    Detection of Tumor Cell Spheroids from Co-cultures Using Phase Contrast Images and Machine Learning Approach by Bayramoglu, Neslihan, Kaakinen, Mika, Eklund, Lauri, Akerfelt, Malin, Nees, Matthias, Kannala, Juho, Heikkila, Janne

    “…Automated image analysis is demanded in cell biology and drug development research. The type of microscopy is one of the considerations in the trade-offs…”
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    Conference Proceeding
  15. 15

    Distribution of aquaporin 4 on sarcolemma of fast-twitch skeletal myofibres by Kaakinen, Mika, Salmela, Paula, Zelenin, Sergey, Metsikkö, Kalervo

    Published in Cell and tissue research (01-09-2007)
    “…The aquaporin 4 (AQP4) water channel is present on the sarcolemma of fast-twitch-type skeletal myofibres. We have examined the distribution of AQP4 in relation…”
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    Journal Article
  16. 16

    Enhancing Transcranial Blood Flow Visualization with Dynamic Light Scattering Technologies: Advances in Quantitative Analysis by Zherebtsov, Evgeny, Sdobnov, Anton, Sieryi, Oleksii, Kaakinen, Mika, Eklund, Lauri, Myllylä, Teemu, Bykov, Alexander, Meglinski, Igor

    Published in Laser & photonics reviews (20-09-2024)
    “…A comparative application of major dynamic light scattering (DLS)‐based image methodologies applied to transcranial cerebral blood flow imaging is presented…”
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    Journal Article
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    Biallelic mutations in human NHLRC2 enhance myofibroblast differentiation in FINCA disease by Paakkola, Teija, Salokas, Kari, Miinalainen, Ilkka, Lehtonen, Siri, Manninen, Aki, Kaakinen, Mika, Ruddock, Lloyd W, Varjosalo, Markku, Kaarteenaho, Riitta, Uusimaa, Johanna, Hinttala, Reetta

    Published in Human molecular genetics (15-12-2018)
    “…Abstract The development of tissue fibrosis is complex and at the present time, not fully understood. Fibrosis, neurodegeneration and cerebral angiomatosis…”
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    Journal Article
  19. 19

    Comparison of Titanium and PEEK Medical Plastic Implant Materials for Their Bacterial Biofilm Formation Properties by Sarfraz, Sonia, Mäntynen, Pilvi-Helinä, Laurila, Marisa, Rossi, Sami, Leikola, Junnu, Kaakinen, Mika, Suojanen, Juho, Reunanen, Justus

    Published in Polymers (01-09-2022)
    “…This study investigated two of the most commonly used CAD–CAM materials for patient-specific reconstruction in craniomaxillofacial surgery. The aim of this…”
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    Journal Article
  20. 20

    Effect of Surface Tooling Techniques of Medical Titanium Implants on Bacterial Biofilm Formation In Vitro by Sarfraz, Sonia, Mäntynen, Pilvi-Helinä, Laurila, Marisa, Suojanen, Juho, Saarnio, Juha, Rossi, Sami, Horelli, Jani, Kaakinen, Mika, Leikola, Junnu, Reunanen, Justus

    Published in Materials (29-04-2022)
    “…The aim of this study was to assess the biofilm formation of , , , and on titanium implants with CAD-CAM tooling techniques. Twenty specimens of titanium were…”
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    Journal Article