Search Results - "Mihm, S"
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Enhancing predictive ability of IL28B-SNPs for SVR in HCV
Published in Alimentary pharmacology & therapeutics (01-01-2012)Get full text
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Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the Liver
Published in International journal of molecular sciences (10-10-2018)“…Inflammatory liver diseases in the absence of pathogens such as intoxication by xenobiotics, cholestatic liver injury, hepatic ischemia-reperfusion injury…”
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1083 RATHER THE ALLELIC VARIATION OF IL28B BUT NOT OF CYP27B1 OR HCV GENOTYPE PREDICT SPONTANEOUS ELIMINATION OF HCV-INFECTION
Published in Journal of hepatology (01-04-2012)Get full text
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Enhanced Expression of Interferon-Regulated Genes in the Liver of Patients with Chronic Hepatitis C Virus Infection: Detection by Suppression-Subtractive Hybridization
Published in Journal of Virology (01-02-2001)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High predictability of a sustained virological response (87%) in chronic hepatitis C virus genotype 1 infection treatment by combined IL28B genotype analysis and γ-glutamyltransferase/alanine aminotransferase ratio: a retrospective single-center study
Published in Digestion (01-01-2012)“…Chronic hepatitis C virus genotype 1 (HCV-G1) infection is treated with pegylated interferon-α and ribavirin. Predictive factors for treatment success are even…”
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Hepatic expression of inducible nitric oxide synthase transcripts in chronic hepatitis C virus infection: Relation to hepatic viral load and liver injury
Published in Hepatology (Baltimore, Md.) (01-08-1997)“…Hepatitis C virus (HCV) causes acute and often also chronic liver disease. Hepatocellular injury might result from both a host response directed to inhibit…”
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Liver infiltrating T lymphocytes express interferon γ and inducible nitric oxide synthase in chronic hepatitis C virus infection
Published in Gut (01-02-2000)“…BACKGROUND Pathogenesis of hepatitis C virus (HCV) associated liver injury is thought to be due to the host antiviral immune response. Using a quantitative,…”
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MxA gene expression in peripheral blood mononuclear cells from patients infected chronically with hepatitis C virus treated with interferon-α
Published in Journal of medical virology (01-11-2000)“…Hepatitis C virus (HCV) infection causes acute and often chronic liver disease. The treatment of choice is interferon‐α (IFN‐α). The proportion of patients…”
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Characterization of gene expression profile in rat Kupffer cells stimulated with IFN-α or IFN-γ
Published in Digestive and liver disease (01-08-2006)“…Kupffer cells are intrasinusoidal space located macrophages with phagocytic capacity. Interferons are cytokines with antiviral, antiproliferative and…”
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Modulation of lymphocyte functions and immune responses by cysteine and cysteine derivatives
Published in The American journal of medicine (30-09-1991)“…Mitogenically stimulated human peripheral blood lymphocytes and T cell clones were found to have weak membrane transport activity for the disulfide cystine but…”
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HCV-RNA positivity in peripheral blood mononuclear cells of patients with chronic HCV infection: does it really mean viral replication?
Published in World journal of gastroenterology : WJG (01-04-2001)“…To analyze the association of HCV-RNA with peripheral blood mononuclear cells (PBMC) and to answer the question whether HCV-RNA positivity in PBMC is due to…”
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High inflammatory activity is associated with an increased amount of IFN-γ transcripts in peripheral blood cells of patients with chronic hepatitis C virus infection
Published in Medical microbiology and immunology (01-09-1996)“…The mechanisms underlying the chronic hepatic inflammatory process in hepatitis C virus (HCV) infection are not well understood. Some models of experimentally…”
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Cryoglobulinemia in chronic hepatitis C virus infection: prevalence, clinical manifestations, response to interferon treatment and analysis of cryoprecipitates
Published in Zeitschrift für Gastroenterologie (01-11-1995)“…Chronic hepatitis C virus infection can be associated with mixed cryoglobulinemia and systemic vasculitis. The pathogenesis remains poorly understood. 55…”
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Interferon-γ inhibits replication of subgenomic and genomic hepatitis C virus RNAs
Published in Hepatology (Baltimore, Md.) (01-03-2002)“…Persistent infection with hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. All treatments known so…”
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Host response to hepatitis C virus
Published in Hepatology (Baltimore, Md.) (01-03-2005)Get full text
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Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype
Published in Hepatology (Baltimore, Md.) (01-03-1997)“…Hepatitis C virus (HCV) causes acute and often chronic hepatitis. On the basis of variations in nucleotide sequence, at least six genotypes and several…”
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Functional relevance of the IRF-1 promoter polymorphism rs2549009 on transcriptional activity in a native genomic environment
Published in Human molecular genetics (01-12-2010)“…Interferon regulatory factor-1 (IRF-1), a transcription regulator involved both in inducing and in mediating the effects of interferon, is encoded by a highly…”
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Expression of the chemokine IP-10 correlates with the accumulation of hepatic IFN-γ and IL-18 mRNA in chronic hepatitis C but not in hepatitis B
Published in Journal of medical virology (01-08-2003)“…The pathogenesis of hepatitis C virus‐induced chronic liver disease is still poorly understood. Previous studies revealed enhanced hepatic expression of the…”
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