Prevalence and Sociodemographic Risk Factors of Soil-Transmitted Helminths in Rural Communities Living in Endemic Foci of Onchocerciasis in Southern Gabon

Prevalence and Sociodemographic Risk Factors of Soil-Transmitted Helminths in Rural Communities Living in Endemic Foci of Onchocerciasis in Southern Gabon

This prospective survey determined the prevalence and intensity of infections due to geohelminths and the associated risk factors in five onchocerciasis-endemic communities in Gabon between January and February 2020. Onchocerciasis endemicity was confirmed by Ov16 IgG testing. STHs were detected usi...

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Bibliographic Details
Published in:Pathogens (Basel) Vol. 13; no. 11; p. 967
Main Authors: Moutongo Mouandza, Reinne, Mourou Mbina, Jean Romain, Moutombi Ditombi, Bridy, Mihindou, Joyce Coella, Moussavou Mabicka, Dimitri Ardrin, Mayandza, Christian, Mbondoukwe, Noe Patrick, Pongui Ngondza, Bedrich, Ndong Akomezoghe, Luccheri, Mawili Mboumba, Denise Patricia, Bouyou Akotet, Marielle Karine
Format: Journal Article
Language:English
Published: Basel MDPI AG 06-11-2024
MDPI
Subjects:
Adults
Age
Antibodies
Chemotherapy
Density
Immunoglobulin G
Infections
Onchocerciasis
Parasites
Parasitic diseases
Risk factors
Rural areas
Rural communities
Sample size
Sociodemographics
Tropical diseases
Gabon
Africa
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Summary:This prospective survey determined the prevalence and intensity of infections due to geohelminths and the associated risk factors in five onchocerciasis-endemic communities in Gabon between January and February 2020. Onchocerciasis endemicity was confirmed by Ov16 IgG testing. STHs were detected using the Kato–Katz techniques. Prevalence and parasite density were analyzed according to age, sex, and onchocerciasis endemicity. STHs were found in 64.8% of participants and were more common in hypoendemic (80.9%) and hyperendemic (63.9%) onchocerciasis communities (p < 0.01). Ascaris lumbricoides (65.5%), Trichuris trichiura (57.1%), and hookworms (17.3%) were prevalent in areas hypoendemic for onchocerciasis (p = 0.04). Male participants were more often infected by hookworms. Adults were more frequently infected by STHs (75.9%) than elders, who were the least infected (39.3%) (p < 0.01). Participants living in sporadic onchocerciasis areas frequently but not significantly harbored a moderate ascariasis load (6960.0 (1068.0–9492.0) eggs per gram) (p = 0.4). The highest parasite density was observed among participants aged 20–45 years (15,336.0 (3888.0–35,028.0)). A low T. trichiuria prevalence was found in all communities. STHs are highly prevalent in hypoendemic and hyperendemic areas and adults. An integrated combined approach of STH and onchocerciasis elimination through efficacious mass drug administration targeting all age groups should be considered.
ISSN:2076-0817
2076-0817
DOI:10.3390/pathogens13110967