Search Results - "Mihaylov, Diana"

Immunosuppressive effects of circulating bile acids in human endotoxemia and septic shock: patients with liver failure are at risk by Leonhardt, Julia, Dorresteijn, Mirrin J, Neugebauer, Sophie, Mihaylov, Diana, Kunze, Julia, Rubio, Ignacio, Hohberger, Frank-Stephan, Leonhardt, Silke, Kiehntopf, Michael, Stahl, Klaus, Bode, Christian, David, Sascha, Wagener, Frank A D T G, Pickkers, Peter, Bauer, Michael

“…Sepsis-induced immunosuppression is a frequent cause of opportunistic infections and death in critically ill patients. A better understanding of the underlying…”
Get full text

Quantification of Bile Acids in Cerebrospinal Fluid: Results of an Observational Trial by Harnisch, Lars-Olav, Neugebauer, Sophie, Mihaylov, Diana, Eidizadeh, Abass, Zechmeister, Bozena, Maier, Ilko, Moerer, Onnen

“…(1) Background: Bile acids, known as aids in intestinal fat digestion and as messenger molecules in serum, can be detected in cerebrospinal fluid (CSF),…”
Get full text

Biomarkers of Cholestasis and Liver Injury in the Early Phase of Acute Respiratory Distress Syndrome and Their Pathophysiological Value by Harnisch, Lars-Olav, Baumann, Sophie, Mihaylov, Diana, Kiehntopf, Michael, Bauer, Michael, Moerer, Onnen, Quintel, Michael

“…Impaired liver function and cholestasis are frequent findings in critically ill patients and are associated with poor outcomes. We tested the hypothesis that…”
Get full text

Determination of individual bile acids in acute respiratory distress syndrome reveals a specific pattern of primary and secondary bile acids and a shift to the acidic pathway as an adaptive response to the critical condition by Harnisch, Lars-Olav, Mihaylov, Diana, Bein, Thomas, Apfelbacher, Christian, Kiehntopf, Michael, Bauer, Michael, Moerer, Onnen, Quintel, Michael

“…Cholestasis and elevated serum bile acid levels are common in critically ill patients. This study aims to define the specific pattern of bile acids associated…”
Get more information

A reduced glycine-to-taurine ratio of conjugated serum bile acids signifies an adaptive mechanism and is an early marker of outcome in acute respiratory distress syndrome by Harnisch, Lars-Olav, Mihaylov, Diana, Bein, Thomas, Apfelbacher, Christian, Moerer, Onnen, Quintel, Michael

“…The accumulation of Bile Acids (BA) in serum is a common finding in critically ill patients and has been found in patients with Acute Respiratory Distress…”
Get full text

Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction by Leonhardt, Julia, Haider, Raphael S., Sponholz, Christoph, Leonhardt, Silke, Drube, Julia, Spengler, Katrin, Mihaylov, Diana, Neugebauer, Sophie, Kiehntopf, Michael, Lambert, Nevin A., Kortgen, Andreas, Bruns, Tony, Tacke, Frank, Hoffmann, Carsten, Bauer, Michael, Heller, Regine

“…Retention of bile acids in the blood is a hallmark of liver failure. Recent studies have shown that increased serum bile acid levels correlate with bacterial…”
Get full text

Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte DysfunctionSummary by Julia Leonhardt, Raphael S. Haider, Christoph Sponholz, Silke Leonhardt, Julia Drube, Katrin Spengler, Diana Mihaylov, Sophie Neugebauer, Michael Kiehntopf, Nevin A. Lambert, Andreas Kortgen, Tony Bruns, Frank Tacke, Carsten Hoffmann, Michael Bauer, Regine Heller

“…Background & Aims: Retention of bile acids in the blood is a hallmark of liver failure. Recent studies have shown that increased serum bile acid levels…”
Get full text