Search Results - "Mihara, Yumiko"
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Importance of Melatonin in Assisted Reproductive Technology and Ovarian Aging
Published in International journal of molecular sciences (08-02-2020)“…Melatonin is probably produced in all cells but is only secreted by the pineal gland. The pineal secretion of melatonin is determined by the light-dark cycle,…”
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Correction: Genome-wide DNA methylation analysis revealed stable DNA methylation status during decidualization in human endometrial stromal cells
Published in BMC genomics (05-04-2024)Get full text
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Genome-wide DNA methylation analysis revealed stable DNA methylation status during decidualization in human endometrial stromal cells
Published in BMC genomics (29-04-2019)“…During decidualization in endometrial stromal cells (ESCs), expressions of a number of genes and epigenetic modifications of histones are altered. However,…”
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Effects of Melatonin on the Transcriptome of Human Granulosa Cells, Fertilization and Blastocyst Formation
Published in International journal of molecular sciences (16-06-2022)“…Melatonin is a promising reagent that can improve assisted reproductive technology (ART) outcomes in infertility patients. However, melatonin is not effective…”
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Integrated Analysis of Transcriptome and Histone Modifications in Granulosa Cells During Ovulation in Female Mice
Published in Endocrinology (Philadelphia) (01-09-2021)“…The ovulatory luteinizing hormone (LH) surge induces rapid changes of gene expression and cellular functions in granulosa cells (GCs) undergoing luteinization…”
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An Integrated Genomic Approach Identifies HOXC8 as an Upstream Regulator in Ovarian Endometrioma
Published in The journal of clinical endocrinology and metabolism (01-12-2020)“…Abstract Purpose To identify the upstream regulators (URs) involved in the onset and pathogenesis of ovarian endometrioma. Methods Recently, a method called…”
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Wilms tumor 1 regulates lipid accumulation in human endometrial stromal cells during decidualization
Published in The Journal of biological chemistry (03-04-2020)“…We previously reported that the transcription factor Wilms tumor 1 (WT1) regulates the expression of insulin-like growth factor-binding protein-1 (IGFBP-1) and…”
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C/EBPβ regulates Vegf gene expression in granulosa cells undergoing luteinization during ovulation in female rats
Published in Scientific reports (24-01-2019)“…The ovulatory LH-surge increases Vegf gene expression in granulosa cells (GCs) undergoing luteinization during ovulation. To understand the factors involved in…”
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Glucose regulates the histone acetylation of gene promoters in decidualizing stromal cells
Published in Reproduction (Cambridge, England) (01-05-2019)“…Decidualization stimuli activate the insulin signaling pathway and increase the glucose uptake in human endometrial stromal cells (ESCs). The inductions of…”
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The clinical outcome of Dienogest treatment followed by in vitro fertilization and embryo transfer in infertile women with endometriosis
Published in Journal of ovarian research (12-12-2019)“…Endometriosis is considered to be the most intractable cause of female infertility. Administering any type of treatment for endometriosis before in vitro…”
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The efficacy of a novel zinc-containing desensitizer CAREDYNE Shield for cervical dentin hypersensitivity: a pilot randomized controlled trial
Published in BMC oral health (17-07-2022)“…Background Recently, a novel zinc-containing desensitizer, CAREDYNE Shield, was developed. This new type of desensitizer induces chemical occlusion of dentinal…”
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Thin endometrium transcriptome analysis reveals a potential mechanism of implantation failure
Published in Reproductive medicine and biology (01-04-2017)“…Aim Although a thin endometrium has been well recognized as a critical factor in implantation failure, little information is available regarding the molecular…”
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Relationship between follicular size and developmental capacity of oocytes under controlled ovarian hyperstimulation in assisted reproductive technologies
Published in Reproductive medicine and biology (01-07-2021)“…Purpose We investigate the relationships between oocyte developmental capacity and follicular size of its origin in Japanese women: those undergoing…”
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Aberrant DNA methylation suppresses expression of estrogen receptor 1 (ESR1) in ovarian endometrioma
Published in Journal of ovarian research (06-02-2019)“…In ovarian endometriomas (OE), the expression statuses of various steroid hormone receptors are altered compared with their expression statuses in eutopic…”
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Nuclear actin assembly is an integral part of decidualization in human endometrial stromal cells
Published in Communications biology (11-07-2024)“…Decidualization of the human endometrium is critical for establishing pregnancy and is entailed by differentiation of endometrial stromal cells (ESCs) into…”
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Combined histological and DNA methylome profiling approaches may provide insights into the pathophysiology of ovarian endometriomas
Published in Reproductive medicine and biology (01-01-2023)“…Purpose To test the theory that invaginated ovarian surface epithelium and endometrial implants on the ovary form ovarian endometriomas. Methods Adhesion sites…”
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The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPβ and WT1 during decidualization of the endometrium
Published in The Journal of biological chemistry (01-10-2021)“…Human endometrial stromal cells (ESCs) differentiate into decidual cells by the action of progesterone, which is essential for implantation and maintenance of…”
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Transcriptional coactivator PGC-1α contributes to decidualization by forming a histone-modifying complex with C/EBPβ and p300
Published in The Journal of biological chemistry (01-05-2022)“…We previously reported that CCAAT/enhancer-binding protein beta (C/EBPβ) is the pioneer factor inducing transcription enhancer mark H3K27 acetylation (H3K27ac)…”
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Transcription factor C/EBPβ induces genome-wide H3K27ac and upregulates gene expression during decidualization of human endometrial stromal cells
Published in Molecular and cellular endocrinology (15-01-2021)“…We previously reported that H3K27 acetylation (H3K27ac) increases throughout the genome during decidualization of human endometrial stromal cells (ESCs)…”
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Long-term melatonin treatment attenuates body weight gain with aging in female mice
Published in Journal of endocrinology (01-10-2021)“…Women usually experience body weight gain with aging, which can put them at risk for many chronic diseases. Previous studies indicated that melatonin treatment…”
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