Search Results - "Mihalová, D."
-
1
Inhibition of oxidative stress in brain during rat adjuvant arthritis by carnosine, trolox and novel trolox-carnosine
Published in Physiological research (01-01-2015)“…Carnosine (CARN) is an anti-glycating agent able to quench superoxide, and to neutralize 4-hydroxynonenal. Trolox-carnosine (CARN-T) was synthesized because of…”
Get full text
Journal Article -
2
Evaluation of the effect of carnosine, its novel derivative trolox-carnosine and trolox in a pre-clinical study focussing on the regulation of immunity
Published in EUROPEAN PHARMACEUTICAL JOURNAL (01-09-2016)“…Abstract The neuroprotective or neurotoxic effects of the products of the kynurenine pathway of tryptophan metabolism highly depend on the action of…”
Get full text
Journal Article -
3
Mesenteric ischemia/reperfusion-induced intestinal and vascular damage : Effect of stobadine
Published in Methods and findings in experimental and clinical pharmacology (2007)“…This study examined the effects of the pyridoindole compound stobadine on intestinal and vascular injury following mesenteric ischemia/reperfusion (I/R) in…”
Get full text
Journal Article -
4
Chondroitin sulfate effect on induced arthritis in rats
Published in Osteoarthritis and cartilage (01-11-2011)“…Summary Objective Rodent models of osteoarthritis and rheumatoid arthritis are useful tools to study these disease processes. Adjuvant arthritis (AAR) is a…”
Get full text
Journal Article -
5
Contribution to safe anti-inflammatory therapy with indomethacin
Published in Central European journal of public health (01-03-2004)“…Non-steroidal anti-inflammatory drugs possess not only therapeutic but also adverse effects, mainly on the gastrointestinal tract. The aim of this pilot study…”
Get full text
Journal Article -
6
Effect of Carnosine in Experimental Arthritis and on Primary Culture Chondrocytes
Published in Oxidative medicine and cellular longevity (01-01-2016)“…We dedicate this paper to the memory of Professor Alexander A. Boldyrev with respect and gratitude…”
Get full text
Journal Article -
7
Gut and vessel alterations induced by mesenteric ischaemia/reperfusion in rats
Published in Central European journal of public health (01-03-2004)“…A rat model of transient occlusion of the superior mesenteric artery was used to study the intestinal and vascular injury induced by ischaemia/ reperfusion…”
Get full text
Journal Article -
8
Hyperbilirubinemia decreases physiological markers in adjuvant-induced arthritis
Published in Physiological research (01-01-2015)“…There is evidence that a higher serum level of bilirubin (BIL) may be a protective factor for autoimmune diseases. We examined the effect of BIL…”
Get full text
Journal Article -
9
Study of new ways of supplementary and combinatory therapy of rheumatoid arthritis with immunomodulators. Glucomannan and Imunoglukán® in adjuvant arthritis
Published in Toxicology and industrial health (01-05-2009)“…We studied the anti-arthritic activity of glucomannan (GM) isolated from Candida utilis and of Imunoglukán®, a beta-(1,3/1,6)-d-glucan (IMG) isolated from…”
Get full text
Journal Article -
10
Pharmacokinetic study of stobadine
Published in Life sciences (1973) (01-10-1999)“…The aim of this paper is to provide a brief overview of most important results of stobadine kinetic studies in rats, dogs, and human volunteers. In these…”
Get full text
Journal Article -
11
Effect of dietary supplementation with the pyridoindole antioxidant stobadine on antioxidant state and ultrastructure of diabetic rat myocardium
Published in Acta diabetologica (2000)“…Consistent with the postulated role of oxidative stress in the etiology of late diabetic complications, pharmacological interventions based on biological…”
Get full text
Journal Article -
12
The pyridoindole antioxidant stobadine attenuates albuminuria, enzymuria, kidney lipid peroxidation and matrix collagen cross-linking in streptozotocin-induced diabetic rats
Published in Methods and findings in experimental and clinical pharmacology (01-11-2002)“…The aim of the present study was to investigate the effect of dietary supplementation with the pyridoindole antioxidant stobadine on kidney status and function…”
Get full text
Journal Article -
13
Antioxidant properties of yeast (1→3)-β- d-glucan studied by electron paramagnetic resonance spectroscopy and its activity in the adjuvant arthritis
Published in Carbohydrate polymers (04-07-2005)“…Radical-scavenging activity of the water-soluble derivative obtained from cell wall of the baker's yeast Saccharomyces cerevisiae was investigated using the…”
Get full text
Journal Article -
14
In vivo effect of pinosylvin and pterostilbene in the animal model of adjuvant arthritis
Published in Neuro-endocrinology letters (2010)“…The aim of this study was to evaluate the effects of pinosylvin (PIN) and pterostilbene (PTE), natural substances from the stilbenoid group, on the development…”
Get more information
Journal Article -
15
Study of new ways of supplementary and combinatory therapy of rheumatoid arthritis with immunomodulators. Glucomannan and Imunoglukan super(+) in adjuvant arthritis
Published in Toxicology and industrial health (01-06-2009)“…We studied the anti-arthritic activity of glucomannan (GM) isolated from Candida utilis and of Imunoglukan super(+), a beta-(1,3/1,6)-d-glucan (IMG) isolated…”
Get full text
Journal Article -
16
Study of new ways of supplementary and combinatory therapy of rheumatoid arthritis with immunomodulators. Glucomannan and Imunoglukan registered in adjuvant arthritis
Published in Toxicology and industrial health (01-05-2009)“…We studied the anti-arthritic activity of glucomannan (GM) isolated from Candida utilis and of Imunoglukan registered , a beta-(1,3/1,6)-d-glucan (IMG)…”
Get full text
Journal Article -
17
Effect of the pyridoindole antioxidant stobadine on development of experimental diabetic cataract and on lens protein oxidation in rats: comparison with vitamin E and BHT
Published in Molecular vision (19-01-2005)“…The aim of this study was to investigate the effect of dietary supplementation with the pyridoindole antioxidant stobadine on the development of diabetic…”
Get full text
Journal Article -
18
Association between tissue gamma-glutamyl-transferase and clinical markers of adjuvant arthritis in Lewis rats
Published in Neuro-endocrinology letters (01-12-2006)“…To assess glucomannan and pyridoindole derivatives for possible antioxidant therapy of rheumatoid arthritis (RA) by using the model of adjuvant arthritis (AA)…”
Get more information
Journal Article -
19
Carnosine inhibits degradation of hyaluronan induced by free radical processes in vitro and improves the redox imbalance in adjuvant arthritis in vivo
Published in Neuro-endocrinology letters (2010)“…New ways of supplementary or combinatory therapy of rheumatoid arthritis (RA) are of great importance. The aim is to find an additive to classical RA therapy…”
Get more information
Journal Article -
20
Effects of sesame oil in the model of adjuvant arthritis
Published in Neuro-endocrinology letters (2009)“…The goal of this study was to evaluate the effect of sesame oil on functional damage induced by adjuvant arthritis (AA) and on changes of selected biochemical…”
Get more information
Journal Article