Search Results - "Mihalik, Nicole E"
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Diversity and relative abundance of ammonia- and nitrite-oxidizing microorganisms in the offshore Namibian hypoxic zone
Published in PloS one (21-05-2019)“…Nitrification, the microbial oxidation of ammonia (NH3) to nitrite (NO2-) and NO2- to nitrate (NO3-), plays a vital role in ocean nitrogen cycling…”
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Formulation and In Vitro Characterization of PLGA/PLGA-PEG Nanoparticles Loaded with Murine Granulocyte-Macrophage Colony-Stimulating Factor
Published in AAPS PharmSciTech (24-06-2021)“…Granulocyte-macrophage colony-stimulating factor (GM-CSF) has demonstrated notable clinical activity in cancer immunotherapy, but it is limited by systemic…”
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Macrophage and Neutrophil Interactions in the Pancreatic Tumor Microenvironment Drive the Pathogenesis of Pancreatic Cancer
Published in Cancers (31-12-2021)“…Despite modest improvements in survival in recent years, pancreatic adenocarcinoma remains a deadly disease with a 5-year survival rate of only 9%. These poor…”
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Dose-Specific Intratumoral GM-CSF Modulates Breast Tumor Oxygenation and Antitumor Immunity
Published in The Journal of immunology (1950) (15-11-2023)“…Abstract GM-CSF has been employed as an adjuvant to cancer immunotherapy with mixed results based on dosage. We previously showed that GM-CSF regulated tumor…”
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Hypoxia-Inducible Factor α Subunits Regulate Tie2-Expressing Macrophages That Influence Tumor Oxygen and Perfusion in Murine Breast Cancer
Published in The Journal of immunology (1950) (15-10-2020)“…Tie2-expressing monocytes/macrophages (TEMs) are a distinct subset of proangiogenic monocytes selectively recruited to tumors in breast cancer. Because of the…”
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Dose-specific intratumoral GM-CSF modulates breast tumor oxygenation and anti-tumor immunity
Published in The Journal of immunology (1950) (15-11-2023)“…GM-CSF has been employed as an adjuvant to cancer immunotherapy with mixed results based on dosage. We previously showed GM-CSF regulated tumor angiogenesis by…”
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