Search Results - "Mihailov, Evelin"

The genetic legacy of the expansion of Turkic-speaking nomads across Eurasia by Yunusbayev, Bayazit, Metspalu, Mait, Metspalu, Ene, Valeev, Albert, Litvinov, Sergei, Valiev, Ruslan, Akhmetova, Vita, Balanovska, Elena, Balanovsky, Oleg, Turdikulova, Shahlo, Dalimova, Dilbar, Nymadawa, Pagbajabyn, Bahmanimehr, Ardeshir, Sahakyan, Hovhannes, Tambets, Kristiina, Fedorova, Sardana, Barashkov, Nikolay, Khidiyatova, Irina, Mihailov, Evelin, Khusainova, Rita, Damba, Larisa, Derenko, Miroslava, Malyarchuk, Boris, Osipova, Ludmila, Voevoda, Mikhail, Yepiskoposyan, Levon, Kivisild, Toomas, Khusnutdinova, Elza, Villems, Richard

“…The Turkic peoples represent a diverse collection of ethnic groups defined by the Turkic languages. These groups have dispersed across a vast area, including…”
Get full text

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank by Wain, Louise V, PhD, Shrine, Nick, PhD, Miller, Suzanne, PhD, Jackson, Victoria E, MSc, Ntalla, Ioanna, PhD, Artigas, María Soler, PhD, Billington, Charlotte K, PhD, Kheirallah, Abdul Kader, BSc, Allen, Richard, MSc, Cook, James P, PhD, Probert, Kelly, BSc, Obeidat, Ma'en, PhD, Bossé, Yohan, PhD, Hao, Ke, ScD, Postma, Dirkje S, Prof, Paré, Peter D, MD, Ramasamy, Adaikalavan, DPhil, Mägi, Reedik, PhD, Mihailov, Evelin, MSc, Reinmaa, Eva, MSc, Melén, Erik, MD, O'Connell, Jared, DPhil, Frangou, Eleni, MSc[Res], Delaneau, Olivier, PhD, Freeman, Colin, PhD, Petkova, Desislava, PhD, McCarthy, Mark, Prof, Sayers, Ian, PhD, Deloukas, Panos, Prof, Hubbard, Richard, Prof, Pavord, Ian, FMedSci, Hansell, Anna L, MBBChir, Thomson, Neil C, Prof, Zeggini, Eleftheria, PhD, Morris, Andrew P, Prof, Marchini, Jonathan, Prof, Strachan, David P, Prof, Tobin, Martin D, Prof, Hall, Ian P, Prof

“…Summary Background Understanding the genetic basis of airflow obstruction and smoking behaviour is key to determining the pathophysiology of chronic…”
Get full text

Copy Number Variations and Cognitive Phenotypes in Unselected Populations by Männik, Katrin, Mägi, Reedik, Macé, Aurélien, Cole, Ben, Guyatt, Anna L, Shihab, Hashem A, Maillard, Anne M, Alavere, Helene, Kolk, Anneli, Reigo, Anu, Mihailov, Evelin, Leitsalu, Liis, Ferreira, Anne-Maud, Nõukas, Margit, Teumer, Alexander, Salvi, Erika, Cusi, Daniele, McGue, Matt, Iacono, William G, Gaunt, Tom R, Beckmann, Jacques S, Jacquemont, Sébastien, Kutalik, Zoltán, Pankratz, Nathan, Timpson, Nicholas, Metspalu, Andres, Reymond, Alexandre

“…IMPORTANCE: The association of copy number variations (CNVs), differing numbers of copies of genetic sequence at locations in the genome, with phenotypes such…”
Get full text

Demographic associations for autoantibodies in disease-free individuals of a European population by Haller-Kikkatalo, Kadri, Alnek, Kristi, Metspalu, Andres, Mihailov, Evelin, Metsküla, Kaja, Kisand, Kalle, Pisarev, Heti, Salumets, Andres, Uibo, Raivo

“…The presence of autoantibodies usually precedes autoimmune disease, but is sometimes considered an incidental finding with no clinical relevance. The…”
Get full text

Mapping the genetic architecture of gene regulation in whole blood by Schramm, Katharina, Marzi, Carola, Schurmann, Claudia, Carstensen, Maren, Reinmaa, Eva, Biffar, Reiner, Eckstein, Gertrud, Gieger, Christian, Grabe, Hans-Jörgen, Homuth, Georg, Kastenmüller, Gabriele, Mägi, Reedik, Metspalu, Andres, Mihailov, Evelin, Peters, Annette, Petersmann, Astrid, Roden, Michael, Strauch, Konstantin, Suhre, Karsten, Teumer, Alexander, Völker, Uwe, Völzke, Henry, Wang-Sattler, Rui, Waldenberger, Melanie, Meitinger, Thomas, Illig, Thomas, Herder, Christian, Grallert, Harald, Prokisch, Holger

“…We aimed to assess whether whole blood expression quantitative trait loci (eQTLs) with effects in cis and trans are robust and can be used to identify…”
Get full text

Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals by Okbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hyeokmoon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Hicks, Barry, Tian, Chao, Hinds, David A., Ahlskog, Rafael, Magnusson, Patrik K. E., Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David J., Freese, Jeremy, Herd, Pamela, Watson, Chelsea, Jala, Jonathan, Conley, Dalton, Koellinger, Philipp D., Johannesson, Magnus, Laibson, David, Meyer, Michelle N., Lee, James J., Kong, Augustine, Yengo, Loic, Cesarini, David, Turley, Patrick, Visscher, Peter M., Beauchamp, Jonathan P., Benjamin, Daniel J., Young, Alexander I.

“…We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately…”
Get full text

Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study by Choi, Karmel W, Chen, Chia-Yen, Stein, Murray B, Klimentidis, Yann C, Wang, Min-Jung, Koenen, Karestan C, Smoller, Jordan W

“…Increasing evidence shows that physical activity is associated with reduced risk for depression, pointing to a potential modifiable target for prevention…”
Get more information

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA by Kettunen, Johannes, Demirkan, Ayşe, Würtz, Peter, Draisma, Harmen H.M., Haller, Toomas, Rawal, Rajesh, Vaarhorst, Anika, Kangas, Antti J., Lyytikäinen, Leo-Pekka, Pirinen, Matti, Pool, René, Sarin, Antti-Pekka, Soininen, Pasi, Tukiainen, Taru, Wang, Qin, Tiainen, Mika, Tynkkynen, Tuulia, Amin, Najaf, Zeller, Tanja, Beekman, Marian, Deelen, Joris, van Dijk, Ko Willems, Esko, Tõnu, Hottenga, Jouke-Jan, van Leeuwen, Elisabeth M, Lehtimäki, Terho, Mihailov, Evelin, Rose, Richard J., de Craen, Anton J.M., Gieger, Christian, Kähönen, Mika, Perola, Markus, Blankenberg, Stefan, Savolainen, Markku J., Verhoeven, Aswin, Viikari, Jorma, Willemsen, Gonneke, Boomsma, Dorret I., van Duijn, Cornelia M., Eriksson, Johan, Jula, Antti, Järvelin, Marjo-Riitta, Kaprio, Jaakko, Metspalu, Andres, Raitakari, Olli, Salomaa, Veikko, Slagboom, P. Eline, Waldenberger, Melanie, Ripatti, Samuli, Ala-Korpela, Mika

“…Genome-wide association studies have identified numerous loci linked with complex diseases, for which the molecular mechanisms remain largely unclear…”
Get full text

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease by Stitziel, Nathan O, Stirrups, Kathleen E, Masca, Nicholas G D, Erdmann, Jeanette, Ferrario, Paola G, König, Inke R, Weeke, Peter E, Webb, Thomas R, Auer, Paul L, Schick, Ursula M, Lu, Yingchang, Zhang, He, Dube, Marie-Pierre, Goel, Anuj, Farrall, Martin, Peloso, Gina M, Won, Hong-Hee, Do, Ron, van Iperen, Erik, Kanoni, Stavroula, Kruppa, Jochen, Mahajan, Anubha, Scott, Robert A, Willenberg, Christina, Braund, Peter S, van Capelleveen, Julian C, Doney, Alex S F, Donnelly, Louise A, Asselta, Rosanna, Merlini, Piera A, Duga, Stefano, Marziliano, Nicola, Denny, Josh C, Shaffer, Christian M, El-Mokhtari, Nour Eddine, Franke, Andre, Gottesman, Omri, Heilmann, Stefanie, Hengstenberg, Christian, Hoffman, Per, Holmen, Oddgeir L, Hveem, Kristian, Jansson, Jan-Håkan, Jöckel, Karl-Heinz, Kessler, Thorsten, Kriebel, Jennifer, Laugwitz, Karl L, Marouli, Eirini, Martinelli, Nicola, McCarthy, Mark I, Van Zuydam, Natalie R, Meisinger, Christa, Esko, Tõnu, Mihailov, Evelin, Escher, Stefan A, Alver, Maris, Moebus, Susanne, Morris, Andrew D, Müller-Nurasyid, Martina, Nikpay, Majid, Olivieri, Oliviero, Lemieux Perreault, Louis-Philippe, AlQarawi, Alaa, Robertson, Neil R, Akinsanya, Karen O, Reilly, Dermot F, Vogt, Thomas F, Yin, Wu, Asselbergs, Folkert W, Kooperberg, Charles, Jackson, Rebecca D, Stahl, Eli, Strauch, Konstantin, Varga, Tibor V, Waldenberger, Melanie, Zeng, Lingyao, Kraja, Aldi T, Liu, Chunyu, Ehret, George B, Newton-Cheh, Christopher, Chasman, Daniel I, Chowdhury, Rajiv, Ferrario, Marco, Ford, Ian, Jukema, J Wouter, Kee, Frank, Kuulasmaa, Kari, Nordestgaard, Børge G, Perola, Markus, Saleheen, Danish, Sattar, Naveed, Surendran, Praveen, Tregouet, David, Young, Robin, Howson, Joanna M M, Butterworth, Adam S, Danesh, John, Ardissino, Diego, Bottinger, Erwin P, Erbel, Raimund

“…Searching for genes in which loss-of-function mutations confer protection against disease is a strategy to identity drug targets. This study reports an…”
Get full text

Genomic analyses inform on migration events during the peopling of Eurasia by Pagani, Luca, Lawson, Daniel John, Jagoda, Evelyn, Mörseburg, Alexander, Eriksson, Anders, Mitt, Mario, Clemente, Florian, Hudjashov, Georgi, DeGiorgio, Michael, Saag, Lauri, Wall, Jeffrey D., Cardona, Alexia, Mägi, Reedik, Sayres, Melissa A. Wilson, Kaewert, Sarah, Inchley, Charlotte, Scheib, Christiana L., Järve, Mari, Karmin, Monika, Jacobs, Guy S., Antao, Tiago, Iliescu, Florin Mircea, Kushniarevich, Alena, Ayub, Qasim, Tyler-Smith, Chris, Xue, Yali, Yunusbayev, Bayazit, Tambets, Kristiina, Mallick, Chandana Basu, Saag, Lehti, Pocheshkhova, Elvira, Andriadze, George, Muller, Craig, Westaway, Michael C., Lambert, David M., Zoraqi, Grigor, Turdikulova, Shahlo, Dalimova, Dilbar, Sabitov, Zhaxylyk, Sultana, Gazi Nurun Nahar, Lachance, Joseph, Tishkoff, Sarah, Momynaliev, Kuvat, Isakova, Jainagul, Damba, Larisa D., Gubina, Marina, Nymadawa, Pagbajabyn, Evseeva, Irina, Atramentova, Lubov, Utevska, Olga, Ricaut, François-Xavier, Brucato, Nicolas, Sudoyo, Herawati, Letellier, Thierry, Cox, Murray P., Barashkov, Nikolay A., Škaro, Vedrana, Mulahasanovic´, Lejla, Primorac, Dragan, Sahakyan, Hovhannes, Mormina, Maru, Eichstaedt, Christina A., Lichman, Daria V., Abdullah, Syafiq, Chaubey, Gyaneshwer, Wee, Joseph T. S., Mihailov, Evelin, Karunas, Alexandra, Litvinov, Sergei, Khusainova, Rita, Ekomasova, Natalya, Akhmetova, Vita, Khidiyatova, Irina, Marjanović, Damir, Yepiskoposyan, Levon, Behar, Doron M., Balanovska, Elena, Metspalu, Andres, Derenko, Miroslava, Malyarchuk, Boris, Voevoda, Mikhail, Fedorova, Sardana A., Osipova, Ludmila P., Lahr, Marta Mirazón, Gerbault, Pascale, Leavesley, Matthew, Migliano, Andrea Bamberg, Petraglia, Michael, Balanovsky, Oleg, Khusnutdinova, Elza K., Metspalu, Ene, Thomas, Mark G., Manica, Andrea, Nielsen, Rasmus, Villems, Richard, Willerslev, Eske, Kivisild, Toomas, Metspalu, Mait

“…Whole-genome sequencing of individuals from 125 populations provides insight into patterns of genetic diversity, natural selection and human demographic…”
Get full text

Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection by Adlam, David, Al-Hussaini, Abtehale, Bouajila, Sara, d’Escamard, Valentina, Huang, Siying, Margaritis, Marios, Nelson, Christopher P., Welch, Catherine A., Jeunemaitre, Xavier, Barnay, Pierre, Rioufol, Gilles, Range, Grégoire, Harbaoui, Brahim, Cayla, Guillaume, Champin, Stanislas, Saint-Etienne, Christophe, Marliere, Stéphanie, Karrillon, Gaëtan, Gerbay, Antoine, Houpe, David, Wong, Claire Mei Yi, Giannoulatou, Eleni, Sweeting, Michael, McGrath-Cadell, Lucy, Dunwoodie, Sally L., Harvey, Richard, Holloway, Cameron, Nikpay, Majid, Goel, Anuj, Won, Hong-Hee, Willenborg, Christina, Kanoni, Stavroula, Kyriakou, Theodosios, Nelson, Christopher P., Webb, Thomas R., Alver, Maris, Auro, Kirsi, Bjonnes, Andrew, Chasman, Daniel I., Franceschini, Nora, Gieger, Christian, Hwang, Shih-Jen, Kleber, Marcus E., Morrison, Alanna, Rose, Lynda M., Scholz, Markus, Smith, Albert V., Uitterlinden, Andre, Beutner, Frank, Gauguier, Dominique, Goodall, Alison H., Gottesman, Omri, Han, Bok-Ghee, Kessler, Thorsten, König, Inke R., Lannfelt, Lars, Lind, Lars, Lindgren, Cecilia M., Mallick, Nadeem H., Meitinger, Thomas, Morris, Andrew P., Nieminen, Markku S., Pedersen, Nancy L., Rasheed, Asif, Sinisalo, Juha, Trompet, Stella, Wang, Laiyuan, Boerwinkle, Eric, Demuth, Ilja, Epstein, Stephen E., Esko, Tõnu, Franco, Oscar H., Franzosi, Maria Grazia, Granger, Christopher B., Harris, Tamara B., Hofman, Albert, Ingelsson, Erik, Iribarren, Carlos, Jukema, J Wouter, Karhunen, Pekka J., Kim, Bong-Jo, Kooner, Jaspal S., Kullo, Iftikhar J., Palmer, Colin N., Perola, Markus, Ridker, Paul M., Ripatti, Samuli, Salomaa, Veikko, Seedorf, Udo, Stewart, Alexandre F., Stott, David J., Thiery, Joachim, Zalloua, Pierre A., Reilly, Muredach P., Clarke, Robert, Watkins, Hugh, Samani, Nilesh J., Farrall, Martin, Hayes, Sharonne N., Samani, Nilesh J.

“…Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndromes (ACS) afflicting predominantly younger to…”
Get full text

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension by Surendran, Praveen, Drenos, Fotios, Witkowska, Kate, Tragante, Vinicius, Freitag, Daniel F, Tinker, Andrew, Harakalova, Magdalena, Rasheed, Asif, Bonnycastle, Lori L, Jackson, Anne U, Narisu, Narisu, Swift, Amy J, Ohlsson, Therese, Matchan, Angela, Stirrups, Kathleen E, Bork-Jensen, Jette, Gjesing, Anette P, Havulinna, Aki S, Zhang, He, Donnelly, Louise A, Neville, Matt J, Robertson, Neil R, Yiorkas, Andrianos M, Herzig, Karl-Heinz, Zhang, Weihua, Trabetti, Elisabetta, Evangelou, Evangelos, Moayyeri, Alireza, Nelson, Christopher P, de Craen, Anton J M, Trompet, Stella, Scott, Robert A, Marioni, Riccardo, Farmaki, Aliki-Eleni, Hallmans, Göran, Hassinen, Maija, Burgess, Stephen, Uria-Nickelsen, Maria, Reilly, Dermot F, Vogt, Thomas F, Traylor, Matthew, Justice, Anne E, Marouli, Eirini, Uusitupa, Matti, Polasek, Ozren, Rudan, Igor, Rolandsson, Olov, Dedoussis, George, Starr, John M, Brown, Morris J, Sattar, Naveed, Packard, Chris J, Mägi, Reedik, Metspalu, Andres, de Boer, Rudolf A, van der Meer, Peter, van der Harst, Pim, Lind, Lars, de Bakker, Paul I W, Korpi-Hyövälti, Eeva, Oksa, Heikki, Linneberg, Allan, Thuesen, Betina, Doney, Alex S F, Morris, Andrew D, Palmer, Colin N A, Holmen, Oddgeir Lingaas, Willer, Cristen J, Palotie, Aarno, Ripatti, Samuli, Majumder, Abdulla al Shafi, Chowdhury, Rajiv, Poulter, Neil, Sever, Peter, Amouyel, Philippe, Arveiler, Dominique, Blankenberg, Stefan, Ferrières, Jean, Müller-Nurasyid, Martina, Veronesi, Giovanni, Virtamo, Jarmo, Deloukas, Panos, Elliott, Paul, Melander, Olle, Kuusisto, Johanna, Laakso, Markku, Padmanabhan, Sandosh, Porteous, David J, Mohlke, Karen L, Pedersen, Oluf, Stringham, Heather M, Newton-Cheh, Christopher, Caulfield, Mark J, Morris, Andrew P, Tomaszewski, Maciej, Saleheen, Danish, Asselbergs, Folkert W, Wain, Louise V, Butterworth, Adam S, Howson, Joanna M M

“…Patricia Munroe, Joanna Howson and colleagues genotype ∼350,000 individuals and identify 30 new blood pressure– or hypertension-associated risk loci. Their…”
Get full text

A recent bottleneck of Y chromosome diversity coincides with a global change in culture by Karmin, Monika, Saag, Lauri, Vicente, Mário, Wilson Sayres, Melissa A, Järve, Mari, Talas, Ulvi Gerst, Rootsi, Siiri, Ilumäe, Anne-Mai, Mägi, Reedik, Mitt, Mario, Pagani, Luca, Puurand, Tarmo, Faltyskova, Zuzana, Clemente, Florian, Cardona, Alexia, Metspalu, Ene, Sahakyan, Hovhannes, Yunusbayev, Bayazit, Hudjashov, Georgi, DeGiorgio, Michael, Loogväli, Eva-Liis, Eichstaedt, Christina, Eelmets, Mikk, Chaubey, Gyaneshwer, Tambets, Kristiina, Litvinov, Sergei, Mormina, Maru, Xue, Yali, Ayub, Qasim, Zoraqi, Grigor, Korneliussen, Thorfinn Sand, Akhatova, Farida, Lachance, Joseph, Tishkoff, Sarah, Momynaliev, Kuvat, Ricaut, François-Xavier, Kusuma, Pradiptajati, Razafindrazaka, Harilanto, Pierron, Denis, Cox, Murray P, Sultana, Gazi Nurun Nahar, Willerslev, Rane, Muller, Craig, Westaway, Michael, Lambert, David, Skaro, Vedrana, Kovačevic, Lejla, Turdikulova, Shahlo, Dalimova, Dilbar, Khusainova, Rita, Trofimova, Natalya, Akhmetova, Vita, Khidiyatova, Irina, Lichman, Daria V, Isakova, Jainagul, Pocheshkhova, Elvira, Sabitov, Zhaxylyk, Barashkov, Nikolay A, Nymadawa, Pagbajabyn, Mihailov, Evelin, Seng, Joseph Wee Tien, Evseeva, Irina, Migliano, Andrea Bamberg, Abdullah, Syafiq, Andriadze, George, Primorac, Dragan, Atramentova, Lubov, Utevska, Olga, Yepiskoposyan, Levon, Marjanovic, Damir, Kushniarevich, Alena, Behar, Doron M, Gilissen, Christian, Vissers, Lisenka, Veltman, Joris A, Balanovska, Elena, Derenko, Miroslava, Malyarchuk, Boris, Metspalu, Andres, Fedorova, Sardana, Eriksson, Anders, Manica, Andrea, Mendez, Fernando L, Karafet, Tatiana M, Veeramah, Krishna R, Bradman, Neil, Hammer, Michael F, Osipova, Ludmila P, Balanovsky, Oleg, Khusnutdinova, Elza K, Johnsen, Knut, Remm, Maido, Thomas, Mark G, Tyler-Smith, Chris, Underhill, Peter A, Willerslev, Eske, Nielsen, Rasmus, Metspalu, Mait, Villems, Richard, Kivisild, Toomas

“…It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya)…”
Get full text

The impact of low-frequency and rare variants on lipid levels by Surakka, Ida, Horikoshi, Momoko, Mägi, Reedik, Sarin, Antti-Pekka, Mahajan, Anubha, Lagou, Vasiliki, Marullo, Letizia, Ferreira, Teresa, Miraglio, Benjamin, Timonen, Sanna, Kettunen, Johannes, Pirinen, Matti, Karjalainen, Juha, Thorleifsson, Gudmar, Hägg, Sara, Hottenga, Jouke-Jan, Isaacs, Aaron, Ladenvall, Claes, Beekman, Marian, Esko, Tõnu, Ried, Janina S, Nelson, Christopher P, Willenborg, Christina, Gustafsson, Stefan, Westra, Harm-Jan, Blades, Matthew, de Craen, Anton J M, de Geus, Eco J, Deelen, Joris, Grallert, Harald, Hamsten, Anders, Havulinna, Aki S, Hengstenberg, Christian, Houwing-Duistermaat, Jeanine J, Hyppönen, Elina, Karssen, Lennart C, Lehtimäki, Terho, Lyssenko, Valeriya, Magnusson, Patrik K E, Mihailov, Evelin, Müller-Nurasyid, Martina, Mpindi, John-Patrick, Pedersen, Nancy L, Penninx, Brenda W J H, Perola, Markus, Pers, Tune H, Peters, Annette, Rung, Johan, Smit, Johannes H, Steinthorsdottir, Valgerdur, Tobin, Martin D, Tsernikova, Natalia, van Leeuwen, Elisabeth M, Viikari, Jorma S, Willems, Sara M, Willemsen, Gonneke, Schunkert, Heribert, Erdmann, Jeanette, Samani, Nilesh J, Kaprio, Jaakko, Lind, Lars, Gieger, Christian, Metspalu, Andres, Slagboom, P Eline, Groop, Leif, van Duijn, Cornelia M, Eriksson, Johan G, Jula, Antti, Salomaa, Veikko, Boomsma, Dorret I, Power, Christine, Raitakari, Olli T, Ingelsson, Erik, Järvelin, Marjo-Riitta, Thorsteinsdottir, Unnur, Franke, Lude, Ikonen, Elina, Kallioniemi, Olli, Pietiäinen, Vilja, Lindgren, Cecilia M, Stefansson, Kari, Palotie, Aarno, McCarthy, Mark I, Morris, Andrew P, Prokopenko, Inga, Ripatti, Samuli

“…Samuli Ripatti and colleagues report the results of a genome-wide association study for circulating lipid levels based on 1000 Genomes Project imputation…”
Get full text

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci by Liu, Mengzhen, Jackson, Victoria E., Melbourne, Carl A., Young, Robin, Batini, Chiara, Afaq, Saima, Agrawal, Arpana, Antoniou, Antonis C., Baumbach, Clemens, Boehnke, Michael, Brazel, David M, Chen, Chu, Corley, Janie, Chou, Yi-Ling, David, Sean P., de Boer, Rudolf A., Dennis, Joe G., Easton, Douglas F., Eaton, Charles, Goate, Alison, Grabe, Hans J., Haessler, Jeff, Hallmans, Göran, Harris, Sarah E., Hattersley, Andrew, Heath, Andrew, Kapoor, Manav, Karpe, Fredrik, Kooner, Jaspal S., Kooperberg, Charles, Laakso, Markku, Langenberg, Claudia, Luan, Jian’an, Madden, Pamela A. F., Mangino, Massimo, Marouli, Eirini, Marten, Jonathan, McGue, Matt, Moayyeri, Alireza, Moitry, Marie, Naheed, Aliya, Nauck, Matthias, Neville, Matthew J., Nielsen, Sune Fallgaard, Perola, Markus, Pharoah, Paul D. P., Rasheed, Asif, Renström, Frida, Rice, John, Rohde, Rebecca, Samuel, Maria, Scholte, Steven H, Scott, Robert A., Shao, Yaming, Smith, Jennifer A., Starr, John M., Stram, Danielle, Stringham, Heather M., Tachmazidou, Ioanna, Tardif, Jean-Claude, Thompson, Deborah J., Tindle, Hilary A., Tragante, Vinicius, Trompet, Stella, Turcot, Valerie, Tyrrell, Jessica, van der Leij, Andries R, van der Meer, Peter, Verweij, Niek, Warren, Helen R., Weiss, Stefan, Wetherill, Leah, Yaghootkar, Hanieh, Jiang, Yu, Chen, Fang, Zhan, Xiaowei, Zhang, Weihua, Zhao, Wei, Zhao, Wei, Zhou, Kaixin, Amouyel, Philippe, Blankenberg, Stefan, Caulfield, Mark J., Chowdhury, Rajiv, Cucca, Francesco, Deary, Ian J., Deloukas, Panos, Ferrario, Marco, Frossard, Philippe, Hall, Ian P., Jansson, Jan-Håkan, Kee, Frank, Munroe, Patricia B., Palmer, Colin N. A., Sattar, Naveed, Spector, Timothy, Zeggini, Eleftheria, Saleheen, Danish, Danesh, John, Tobin, Martin D.

“…Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen…”
Get full text

Identification of seven loci affecting mean telomere length and their association with disease by Codd, Veryan, Nelson, Christopher P, Albrecht, Eva, Mangino, Massimo, Deelen, Joris, Buxton, Jessica L, Hottenga, Jouke Jan, Fischer, Krista, Esko, Tõnu, Surakka, Ida, Broer, Linda, Nyholt, Dale R, Leach, Irene Mateo, Salo, Perttu, Hägg, Sara, Matthews, Mary K, Palmen, Jutta, Norata, Giuseppe D, O'Reilly, Paul F, Saleheen, Danish, Amin, Najaf, Balmforth, Anthony J, Beekman, Marian, de Boer, Rudolf A, Böhringer, Stefan, Braund, Peter S, Burton, Paul R, Craen, Anton J Mde, Denniff, Matthew, Dong, Yanbin, Douroudis, Konstantinos, Dubinina, Elena, Eriksson, Johan G, Garlaschelli, Katia, Guo, Dehuang, Hartikainen, Anna-Liisa, Henders, Anjali K, Houwing-Duistermaat, Jeanine J, Kananen, Laura, Karssen, Lennart C, Kettunen, Johannes, Klopp, Norman, Lagou, Vasiliki, van Leeuwen, Elisabeth M, Madden, Pamela A, Mägi, Reedik, Magnusson, Patrik K E, Männistö, Satu, McCarthy, Mark I, Medland, Sarah E, Mihailov, Evelin, Montgomery, Grant W, Oostra, Ben A, Palotie, Aarno, Peters, Annette, Pollard, Helen, Pouta, Anneli, Prokopenko, Inga, Ripatti, Samuli, Salomaa, Veikko, Suchiman, H Eka D, Valdes, Ana M, Verweij, Niek, Viñuela, Ana, Wang, Xiaoling, Wichmann, H-Erich, Widen, Elisabeth, Willemsen, Gonneke, Wright, Margaret J, Xia, Kai, Xiao, Xiangjun, van Veldhuisen, Dirk J, Catapano, Alberico L, Tobin, Martin D, Hall, Alistair S, Blakemore, Alexandra I F, van Gilst, Wiek H, Zhu, Haidong, Erdmann, Jeanette, Reilly, Muredach P, Kathiresan, Sekar, Schunkert, Heribert, Talmud, Philippa J, Pedersen, Nancy L, Perola, Markus, Ouwehand, Willem, Kaprio, Jaakko, Martin, Nicholas G, van Duijn, Cornelia M, Hovatta, Iiris, Gieger, Christian, Metspalu, Andres, Boomsma, Dorret I, Jarvelin, Marjo-Riitta, Slagboom, P Eline, Thompson, John R, Spector, Tim D, van der Harst, Pim, Samani, Nilesh J

“…Nilesh Samani and colleagues report a meta-analysis of genome-wide association studies for mean leukocyte telomere length in 37,684 individuals, with…”
Get full text

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank by Shen, Xueyi, Howard, David M., Adams, Mark J., Hill, W. David, Clarke, Toni-Kim, Deary, Ian J., Whalley, Heather C., McIntosh, Andrew M.

“…Depression is a leading cause of worldwide disability but there remains considerable uncertainty regarding its neural and behavioural associations. Here, using…”
Get full text

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis by Benyamin, Beben, Esko, Tonu, Ried, Janina S., Radhakrishnan, Aparna, Vermeulen, Sita H., Traglia, Michela, Gögele, Martin, Anderson, Denise, Broer, Linda, Podmore, Clara, Luan, Jian’an, Kutalik, Zoltan, Sanna, Serena, van der Meer, Peter, Tanaka, Toshiko, Wang, Fudi, Westra, Harm-Jan, Franke, Lude, Mihailov, Evelin, Milani, Lili, Hälldin, Jonas, Winkelmann, Juliane, Meitinger, Thomas, Thiery, Joachim, Peters, Annette, Waldenberger, Melanie, Rendon, Augusto, Jolley, Jennifer, Sambrook, Jennifer, Kiemeney, Lambertus A., Sweep, Fred C., Sala, Cinzia F., Schwienbacher, Christine, Pichler, Irene, Hui, Jennie, Demirkan, Ayse, Isaacs, Aaron, Amin, Najaf, Steri, Maristella, Waeber, Gérard, Verweij, Niek, Powell, Joseph E., Nyholt, Dale R., Heath, Andrew C., Madden, Pamela A. F., Visscher, Peter M., Wright, Margaret J., Montgomery, Grant W., Martin, Nicholas G., Hernandez, Dena, Bandinelli, Stefania, van der Harst, Pim, Uda, Manuela, Vollenweider, Peter, Scott, Robert A., Langenberg, Claudia, Wareham, Nicholas J., van Duijn, Cornelia, Beilby, John, Pramstaller, Peter P., Hicks, Andrew A., Ouwehand, Willem H., Oexle, Konrad, Gieger, Christian, Metspalu, Andres, Camaschella, Clara, Toniolo, Daniela, Swinkels, Dorine W., Whitfield, John B.

“…Variation in body iron is associated with or causes diseases, including anaemia and iron overload. Here, we analyse genetic association data on biochemical…”
Get full text

Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder by de Moor, Marleen H M, van den Berg, Stéphanie M, Verweij, Karin J H, Krueger, Robert F, Luciano, Michelle, Arias Vasquez, Alejandro, Matteson, Lindsay K, Derringer, Jaime, Esko, Tõnu, Amin, Najaf, Gordon, Scott D, Hansell, Narelle K, Hart, Amy B, Seppälä, Ilkka, Huffman, Jennifer E, Konte, Bettina, Lahti, Jari, Lee, Minyoung, Miller, Mike, Nutile, Teresa, Tanaka, Toshiko, Teumer, Alexander, Viktorin, Alexander, Wedenoja, Juho, Abecasis, Goncalo R, Adkins, Daniel E, Agrawal, Arpana, Allik, Jüri, Appel, Katja, Bigdeli, Timothy B, Busonero, Fabio, Campbell, Harry, Costa, Paul T, Davey Smith, George, Davies, Gail, de Wit, Harriet, Ding, Jun, Engelhardt, Barbara E, Eriksson, Johan G, Fedko, Iryna O, Ferrucci, Luigi, Franke, Barbara, Giegling, Ina, Grucza, Richard, Hartmann, Annette M, Heath, Andrew C, Heinonen, Kati, Henders, Anjali K, Homuth, Georg, Hottenga, Jouke-Jan, Iacono, William G, Janzing, Joost, Jokela, Markus, Karlsson, Robert, Kemp, John P, Kirkpatrick, Matthew G, Latvala, Antti, Lehtimäki, Terho, Liewald, David C, Madden, Pamela A F, Magri, Chiara, Magnusson, Patrik K E, Marten, Jonathan, Maschio, Andrea, Medland, Sarah E, Mihailov, Evelin, Milaneschi, Yuri, Montgomery, Grant W, Nauck, Matthias, Ouwens, Klaasjan G, Palotie, Aarno, Pettersson, Erik, Polasek, Ozren, Qian, Yong, Pulkki-Råback, Laura, Raitakari, Olli T, Realo, Anu, Rose, Richard J, Ruggiero, Daniela, Schmidt, Carsten O, Slutske, Wendy S, Sorice, Rossella, Starr, John M, St Pourcain, Beate, Sutin, Angelina R, Timpson, Nicholas J, Trochet, Holly, Vermeulen, Sita, Vuoksimaa, Eero, Widen, Elisabeth, Wouda, Jasper, Wright, Margaret J, Zgaga, Lina, Porteous, David, Minelli, Alessandra, Palmer, Abraham A, Rujescu, Dan, Ciullo, Marina, Hayward, Caroline, Rudan, Igor

“…Neuroticism is a pervasive risk factor for psychiatric conditions. It genetically overlaps with major depressive disorder (MDD) and is therefore an important…”
Get more information

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness by Willems, Sara M., Wright, Daniel J., Day, Felix R., Trajanoska, Katerina, Joshi, Peter K., Morris, John A., Matteini, Amy M., Garton, Fleur C., Grarup, Niels, Oskolkov, Nikolay, Thalamuthu, Anbupalam, Mangino, Massimo, Liu, Jun, Demirkan, Ayse, Lek, Monkol, Xu, Liwen, Wang, Guan, Oldmeadow, Christopher, Gaulton, Kyle J., Lotta, Luca A., Miyamoto-Mikami, Eri, Rivas, Manuel A., White, Tom, Loh, Po-Ru, Aadahl, Mette, Amin, Najaf, Attia, John R., Austin, Krista, Benyamin, Beben, Brage, Søren, Cheng, Yu-Ching, Cięszczyk, Paweł, Derave, Wim, Eriksson, Karl-Fredrik, Eynon, Nir, Linneberg, Allan, Lucia, Alejandro, Massidda, Myosotis, Mitchell, Braxton D., Miyachi, Motohiko, Murakami, Haruka, Padmanabhan, Sandosh, Pandey, Ashutosh, Papadimitriou, Ioannis, Rajpal, Deepak K., Sale, Craig, Schnurr, Theresia M., Sessa, Francesco, Shrine, Nick, Tobin, Martin D., Varley, Ian, Wain, Louise V., Wray, Naomi R., Lindgren, Cecilia M., MacArthur, Daniel G., Waterworth, Dawn M., McCarthy, Mark I., Pedersen, Oluf, Khaw, Kay-Tee, Kiel, Douglas P., Pitsiladis, Yannis, Fuku, Noriyuki, Franks, Paul W., North, Kathryn N., van Duijn, Cornelia M., Mather, Karen A., Hansen, Torben, Hansson, Ola, Spector, Tim, Murabito, Joanne M., Richards, J. Brent, Rivadeneira, Fernando, Langenberg, Claudia, Perry, John R. B., Wareham, Nick J., Scott, Robert A.

“…Hand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor of a range of morbidities and all-cause mortality. To…”
Get full text