Search Results - "Mihaela Munteanu"

Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study by Flinn, Ian W., van der Jagt, Richard, Kahl, Brad S., Wood, Peter, Hawkins, Tim E., MacDonald, David, Hertzberg, Mark, Kwan, Yiu-Lam, Simpson, David, Craig, Michael, Kolibaba, Kathryn, Issa, Samar, Clementi, Regina, Hallman, Doreen M., Munteanu, Mihaela, Chen, Ling, Burke, John M.

“…This randomized, noninferiority (NI), global, phase 3 study evaluated the efficacy and safety of bendamustine plus rituximab (BR) vs a standard…”
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Pembrolizumab with platinum-based chemotherapy with or without epacadostat as first-line treatment for metastatic non-small cell lung cancer: a randomized, partially double-blind, placebo-controlled phase II study by Boyer, Michael, Hui, Rina, Urban, Damien, Clingan, Philip, Su, Wu-Chou, Devaux, Celine, Gadgeel, Shirish, Garassino, Marina, Leopold, Lance, Daniel, Jeannie, Munteanu, Mihaela C, Samkari, Ayman, Luo, Yiwen, Abreu, Delvys Rodriguez

“…The combination of the checkpoint inhibitor (CPI) pembrolizumab and platinum-based chemotherapy is effective frontline therapy for advanced non-small cell lung…”
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Safety, tolerability, and preliminary activity of IMGN529, a CD37-targeted antibody-drug conjugate, in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: a dose-escalation, phase I study by Stathis, Anastasios, Flinn, Ian W., Madan, Sumit, Maddocks, Kami, Freedman, Arnold, Weitman, Steven, Zucca, Emanuele, Munteanu, Mihaela C., Lia Palomba, M.

“…Summary Background CD37 is expressed on B-cell lymphoid malignancies, thus making it an attractive candidate for targeted therapy in non-Hodgkin lymphoma…”
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Epacadostat plus pembrolizumab versus placebo plus pembrolizumab as first-line treatment for metastatic non-small cell lung cancer with high levels of programmed death-ligand 1: a randomized, double-blind phase 2 study by Tokito, Takaaki, Kolesnik, Oleksii, Sørensen, Jens, Artac, Mehmet, Quintela, Martín Lázaro, Lee, Jong-Seok, Hussein, Maen, Pless, Miklos, Paz-Ares, Luis, Leopold, Lance, Daniel, Jeannie, Munteanu, Mihaela, Samkari, Ayman, Xu, Lu, Butts, Charles

“…Pembrolizumab is a first-line therapy for certain patients with advanced/metastatic non-small cell lung cancer (NSCLC). Combining pembrolizumab with other…”
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Focal segmental glomerulosclerosis in children complicated by posterior reversible encephalopathy syndrome by Stârcea, Magdalena, Gavrilovici, Cristina, Munteanu, Mihaela, Miron, Ingrith

“…An uncommon side effect of cyclosporine A (CsA) use is posterior reversible encephalopathy syndrome (PRES). PRES usually develops because of disturbed capacity…”
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A randomized, open-label, phase 3 trial of pembrolizumab plus epacadostat versus sunitinib or pazopanib as first-line treatment for metastatic renal cell carcinoma (KEYNOTE-679/ECHO-302) by Lara, Jr, Primo N, Villanueva, Luis, Ibanez, Carolina, Erman, Mustafa, Lee, Jae Lyun, Heinrich, Daniel, Lipatov, Oleg Nikolaevich, Gedye, Craig, Gokmen, Erhan, Acevedo, Alejandro, Semenov, Andrey, Park, Se Hoon, Gafanov, Rustem Airatovich, Kose, Fatih, Jones, Mark, Du, Xiaoqi, Munteanu, Mihaela, Perini, Rodolfo, Choueiri, Toni K, Motzer, Robert J

“…Immunotherapy-based combinations have emerged as standard therapies for patients with metastatic renal cell carcinoma (mRCC). Pembrolizumab, a PD-1 inhibitor,…”
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Epacadostat plus pembrolizumab versus placebo plus pembrolizumab for advanced urothelial carcinoma: results from the randomized phase III ECHO-303/KEYNOTE-698 study by Cicin, Irfan, Plimack, Elizabeth R, Gurney, Howard, Leibowitz, Raya, Alekseev, Boris Y, Parnis, Francis X, Peer, Avivit, Necchi, Andrea, Bellmunt, Joaquim, Nishiyama, Hiroyuki, Clark, Jason, Munteanu, Mihaela, Kataria, Ritesh, Jia, Calvin, Powles, Thomas, Sternberg, Cora N

“…Indoleamine 2,3-dioxygenase 1 (IDO1) levels correlate with poor outcomes in urothelial carcinoma (UC). IDO1 and programmed death-ligand 1 (PD-L1) are often…”
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Pembrolizumab plus epacadostat in patients with recurrent/metastatic head and neck squamous cell carcinoma (KEYNOTE-669/ECHO-304): a phase 3, randomized, open-label study by Cho, Byoung Chul, Braña, Irene, Cirauqui, Beatriz, Aksoy, Sercan, Couture, Felix, Hong, Ruey-Long, Miller, Jr, Wilson H, Chaves-Conde, Manuel, Teixeira, Margarida, Leopold, Lance, Munteanu, Mihaela, Ge, Joy Yang, Swaby, Ramona F, Hughes, Brett G M

“…Advanced head and neck squamous cell carcinoma (HNSCC) has a poor prognosis, and new treatment options are needed. Combining immunotherapies with differing…”
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Pembrolizumab plus either epacadostat or placebo for cisplatin-ineligible urothelial carcinoma: results from the ECHO-307/KEYNOTE-672 study by Necchi, Andrea, Van der Heijden, Michiel S, Trukhin, Dmytro, Peer, Avivit, Gurney, Howard, Alekseev, Boris Y, Parnis, Francis X, Leibowitz, Raya, De Santis, Maria, Grivas, Petros, Clark, Jason, Munteanu, Mihaela, Kataria, Ritesh, Jia, Calvin, Balar, Arjun V, de Wit, Ronald

“…Indoleamine 2,3- dioxygenase 1 (IDO1) is an immunosuppressive enzyme that has been correlated with shorter disease-specific survival in patients with…”
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Giant Villous Adenoma of the Rectum With Prolapse: Case Report by Munteanu, Iurii, Mihaela, Munteanu, Popescu, Silvia, Slavu, Iulian M, Oprescu Macovei, Anca, Cochior, Daniel

“…Colorectal polyps, frequently adenomas, are common in older adults, with villous adenomas being a notable subset due to their potential for significant…”
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The safety and tolerability of epacadostat alone and in combination with pembrolizumab in patients with advanced solid tumors: results from a first-in-Japanese phase I study (KEYNOTE-434) by Doi, Toshihiko, Fujiwara, Yutaka, Shitara, Kohei, Shimizu, Toshio, Yonemori, Kan, Matsubara, Nobuaki, Ohno, Izumi, Kogawa, Takahiro, Naito, Yoichi, Leopold, Lance, Munteanu, Mihaela, Yatsuzuka, Naoyoshi, Han, Shi Rong, Samkari, Ayman, Yamamoto, Noboru

“…Summary Purpose Part A of the open-label, phase I KEYNOTE-434 study evaluated the safety and tolerability of epacadostat, an indoleamine 2,3-dioxygenase-1…”
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Implications in Halotherapy of Aerosols from the Salt Mine Targu Ocna-Structural-Functional Characteristics by Antonovici Munteanu, Mihaela Orlanda, Sandu, Ioan Gabriel, Vasilache, Viorica, Sandu, Andrei Victor, Arcana, Stefanita, Arcana, Raluca Ioana, Sandu, Ion

“…The paper presents the evolution of the concentration level for four particle size groups of microaerosols (1.0, 2.5, 4.0 and 10.0 µm) in correlation with the…”
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Potent Anti-HIV Chemokine Analogs Direct Post-Endocytic Sorting of CCR5 by Bönsch, Claudia, Munteanu, Mihaela, Rossitto-Borlat, Irène, Fürstenberg, Alexandre, Hartley, Oliver

“…G protein-coupled receptors (GPCRs) are desensitized and internalized following activation. They are then subjected to post-endocytic sorting (degradation,…”
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Pembrolizumab (pembro) plus epacadostat or placebo for locally advanced or metastatic urothelial carcinoma (UC) after failure of first-line platinum-containing chemotherapy: KEYNOTE-698/ECHO-303 by Powles, Thomas, Bellmunt, Joaquim, Petrylak, Daniel Peter, Fong, Lawrence, Nishiyama, Hiroyuki, Sternberg, Cora N., Chen, Mei, Pang, Lei, Munteanu, Mihaela, Zhao, Yufan, Smith, David C.

“…Abstract only…”
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Phase I Evaluation of a Fully Human Anti–αv Integrin Monoclonal Antibody (CNTO 95) in Patients with Advanced Solid Tumors by MULLAMITHA, Saifee A, TON, Nhuan C, HOPE, Lynn, VALLE, Juan W, RADFORD, John A, LAWRANCE, Jeremy, SAUNDERS, Mark P, MUNTEANU, Mihaela C, NAKADA, Marian T, NEMETH, Jeffrey A, DAVIS, Hugh M, QUN JIAO, PARKER, Geoff J. M, PRABHAKAR, Uma, ZHIHUI LANG, CORRINGHAM, Robert E, BECKMAN, Robert A, JAYSON, Gordon C, JACKSON, Alan, JULYAN, Peter J, ROBERTS, Caleb, BUONACCORSI, Gio A, WATSON, Yvonne, DAVIES, Karen, CHEUNG, Sue

“…Purpose: A fully human monoclonal antibody to anti–α v integrins (CNTO 95) has been shown to inhibit angiogenesis and tumor growth in preclinical studies. We…”
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Enhancing the Performance of a Simulated WWTP: Comparative Analysis of Control Strategies for the BSM2 Model by Roșu, Bogdan, Mocanu, George Dănuț, Pila, Mihaela Munteanu, Murariu, Gabriel, Roșu, Adrian, Arseni, Maxim

“…This study aimed to improve the performance of a wastewater treatment plant (WWTP) simulated with Benchmark Model No. 2 (BSM2). To achieve this objective,…”
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Results of a phase II study of bendamustine and ofatumumab in untreated indolent B cell non-Hodgkin’s lymphoma by Czuczman, Myron S., Kahanic, Stephen, Forero, Andres, Davis, Glen, Munteanu, Mihaela, Van Den Neste, Eric, Offner, Fritz, Bron, Dominique, Quick, Donald, Fowler, Nathan

“…The efficacy/tolerability of bendamustine, a unique alkylator, plus ofatumumab, a human anti-CD20 monoclonal antibody, was evaluated for previously untreated…”
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An evaluation of the potential for drug–drug interactions between bendamustine and rituximab in indolent non-Hodgkin lymphoma and mantle cell lymphoma by Darwish, Mona, Burke, John M., Hellriegel, Edward, Robertson, Philmore, Phillips, Luann, Ludwig, Elizabeth, Munteanu, Mihaela C., Bond, Mary

“…Purpose Bendamustine plus rituximab has been reported to be effective in treating lymphoid malignancies. This analysis investigated the potential for drug–drug…”
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Use of New and Light Materials in Automotive Engineering for Towing System by Petrici, Andrei Victor, Scutaru, Maria Luminita, Munteanu, Violeta Mihaela, Vlase, Sorin

“…Towing systems are an important component in the automobile industry, having to meet specific quality and resistance conditions. In most cases, the towbar is…”
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Exploitation of Hunting and Fishing Tourism in Galați County, Romania by Camară, Gabriel, Munteanu, Mihaela-Violeta

“…Galați county is a geographical area that is less valued in terms of tourism, but which benefits by a natural tourism potential. The aim of this study is to…”
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